Makrecka-Kuka M

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MiPsociety
COST Action CA15203 MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping


 

Makrecka-Kuka M


MitoPedia topics: EAGLE 

COST: Member COST WG1: WG1 COST WG2: WG2

COST WG4: WG4

COST ECI: ECI

Dissemination Coordinator - Management Committee MitoEAGLE
Name Makrecka-Kuka Marina, PhD

ORCID ID

Institution
Marina Makrecka
Laboratory of Pharmaceutical Pharmacology,

Latvian Institute of Organic Synthesis, LV

Address Aizkraukles Street 21, 1006
City Riga
State/Province
Country Latvia
Email makrecka@farm.osi.lv
Weblink http://www.osi.lv/en/
O2k-Network Lab LV Riga Makrecka-Kuka M


MitoEAGLE

We are mostly interested in two WG: (1) Since we are working mostly with heart and muscles, we are interested in WG 2 - MitoEAGLE data repository in muscle and other tissues. (2) WG 1 - Standard operating procedures and user requirement document: Protocols, terminology, documentation. Since we have an expertise in fatty acid metabolism, we are specially interested in experimental protocols for the evaluation of mitochondrial capacities regarding fatty acid metabolism. Of course our parts of the WG are also in our interest. - Marina Makrecka-Kuka, Edgars Liepinsh (2016).
Marina Makrecka (right) and Sarka Davidikova exploring the world of the O2k


IOC105 O2k-Workshop 2015-08-27









Labels: Field of research: Basic, Pharmacological 



Publications

 PublishedReference
Gnaiger 2019 MitoFit Preprint Arch2019Gnaiger E, Aasander Frostner E, Abdul Karim N, Abumrad NA, Acuna-Castroviejo D, Adiele RC, et al (2019) Mitochondrial respiratory states and rates. MitoFit Preprint Arch doi:10.26124/mitofit:190001.v5.
Makrecka-Kuka 2017 Toxicol Lett2017Makrecka-Kuka M, Volska K, Antone U, Vilskersts R, Grinberga S, Bandere D, Liepinsh E, Dambrova M (2017) Trimethylamine N-oxide impairs pyruvate and fatty acid oxidation in cardiac mitochondria. Toxicol Lett 267:32-8.
Liepinsh 2016 Biochem J2016Liepinsh E, Makrecka-Kuka M, Volska K, Kuka J, Makarova E, Antone U, Sevostjanovs E, Vilskersts R, Strods A, Tars K, Dambrova M (2016) Long-chain acylcarnitines determine ischaemia/reperfusion-induced damage in heart mitochondria. Biochem J 473:1191-202.
MiPNet20.16 IOC105 Riga2015-08-27
O2k-Network
Riga LV, 2015 Aug 27. Oroboros O2k-Workshop on high-resolution respirometry (HRR) and O2k-Fluorometry - innovabalt, IOC105.
Makrecka-Kuka 2015 Biomolecules2015
O2k-Protocols contents
Makrecka-Kuka M, Krumschnabel G, Gnaiger E (2015) High-resolution respirometry for simultaneous measurement of oxygen and hydrogen peroxide fluxes in permeabilized cells, tissue homogenate and isolated mitochondria. Biomolecules 5:1319-38.

Abstracts

 PublishedReference
Volska 2018 MiP20182018
Kristina Volska
The mechanisms of long-chain acylcarnitine accumulation during ischemia.
Kidere 2018 MiP20182018
Dita Kidere
Cytoplasmic hybrid cells as a model to characterize the effect of the mtDNA mutations on the OXPHOS system.
Kidere 2018 MiPschool Tromso E22018
Dita Kidere
Cytoplasmic hybrid cells as a model to characterize the OXPHOS system: control sample with glutamate metabolism defect.
Stelfa 2018 MiP20182018
MiPsociety
Neuroprotective compound R-phenibut protects brain mitochondria against anoxia-reoxygenation damage in vitro.
Makrecka-Kuka 2018 MiPschool Tromso E12018
Marina Makrecka-Kuka
Cardiac fatty acid oxidation: from in vitro to in vivo.
Makrecka-Kuka 2018 MiP20182018
Marina Makrecka-Kuka
Fatty acid oxidation in brain: from aging to ischemia and sepsis.
Kuka 2018 MiP20182018
MiPsociety
The discovery of methyl-GBB - acylcarnitine lowering as an effective strategy to treat cardiometabolic diseases.
Makarova 2018 MiP20182018
MiPsociety
Plasma concentrations of fatty acids and acylcarnitines as biomarkers for diagnosis of insulin resistance in adipose and muscle tissues.
Makrecka-Kuka 2017 Abstract MITOEAGLE Barcelona2017
COST Action MITOEAGLE
Fatty acid oxidation evaluation in mitochondria.
Makrecka-Kuka 2017 MiP20172017
Marina Makrecka-Kruka
Heart, brain and kidneys: who will survive? Tissue-specific changes in mitochondrial function in the experimental model of endotoxemia.
Makrecka-Kuka 2016 Abstract MitoFit Science Camp 20162016Long-chain acylCoAs vs acylcarnitines in mitochondrial bioenergetics: from in vitro to in vivo.
Makrecka 2015 Fatty Acid Oxidation O2k-Network Discussion Forum2015Makrecka 2015 Fatty Acid Oxidation O2k-Network Discussion Forum
Makrecka 2013 Abstract MiP20132013Makrecka-Kuka M, Volska K, Kuka J, Liepins E, Dambrova M (2013) The accumulation of long chain acyl-carnitines is a major cause of mitochondrial damage during ischemia. Mitochondr Physiol Network 18.08.
Volska 2013 Abstract MiP20132013Volska K, Makrecka-Kuka M, Svalbe B, Dambrova M (2013) The inhibitor of L-carnitine biosynthesis protects brain mitochondria against anoxia-reoxygenation injury. Mitochondr Physiol Network 18.08.

MitoEAGLE Inclusiveness Target Countries - Conference Grant

Scientific report - MiP2017


Participated at


Visiting scientist in the Oroboros MitoFit Laboratory

O2k-Network

Marina Makrecka-Kuka: Visiting scientist at the Oroboros MitoFit Laboratory

  • March 12 to 29 2018
  • August to October 2014