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• Wang 2019 Metabolism
  ...L, Pan JQ, Shu G, Jiang QY, Yin YL, Zhang L (2019) LSD1 mediates microbial metabolite butyrate-induced thermogenesis in brown and white adipose tissue. Metabolis ...ylase and important regulator of thermogenesis, in mediating gut microbial metabolite butyrate regulation of thermogenesis.
  3 KB (418 words) - 16:34, 28 November 2019
• NS e-input
  ...glutamate&malate), but of succinate (S) simultaneously, since [[metabolite depletion]] in the absence of succinate prevents a significant stimulation of S-linke
  1 KB (149 words) - 18:49, 1 January 2021
• Billingham 2022 Nat Immunol
  ...common metabolite that is diminished by mitochondrial ETC inhibitors. PCr depletion decreased ATP levels and NLRP3 inflammasome activation. Thus, the mitochond
  2 KB (256 words) - 14:56, 4 April 2023
• NS-pathway control state
  ...rgent electron-input into the [[Q-junction]], to compensate for metabolite depletion into the incubation medium. NS in combination exerts an [[additive effect o |mitopedia topic=Substrate and metabolite, EAGLE
  4 KB (604 words) - 08:32, 25 November 2023
• FN
  ...rgent electron-input into the [[Q-junction]], to compensate for metabolite depletion into the incubation medium. FS in combination exerts an [[additive effect o
  2 KB (311 words) - 19:57, 1 January 2021
• NADH electron transfer-pathway state
  ...]) is largely substrate-limited in N-linked respiration, due to metabolite depletion into the incubation medium. The residual involvement of S-linked respiratio
  3 KB (409 words) - 08:06, 25 November 2023
• MacDonald 2018 IOC130
  .../sub>O₂ typically present in cells would favor emission of this metabolite but the scavenging systems would prevent its accumulation.
  3 KB (419 words) - 14:04, 23 May 2018
• Van Eunen 2016 BMC Biol
  ...computational model. While molecular competition did not affect the plasma metabolite profiles during MCAD deficiency, it was a key factor in explaining the char ::* “The resulting flux decline was mediated by a self-amplifying depletion of CoASH.”
  4 KB (583 words) - 17:17, 12 February 2018
• Kumar 2023 J Nutr Biochem
  ...ation of eukaryotic initiation factor 2α are also reversed by Ile. Genetic depletion studies showed that Ile responses are independent of the amino acid transpo
  3 KB (340 words) - 16:54, 23 November 2023
• Risiglione 2020 Int J Mol Sci
  ...re it inhibits complex I of the electron transport chain, resulting in ATP depletion and neuronal impairment/death. So far, MPP⁺ is recognized as a v
  3 KB (367 words) - 17:36, 5 October 2023
• Chausse 2020 Brain Behav Immun
  ...oxidative stress, neuronal dysfunction and death. Notably, pharmacological depletion of microglia or treatment with itaconate resulted in effective neuroprotect
  3 KB (354 words) - 21:38, 20 August 2020
• Gnaiger 2009 Int J Biochem Cell Biol
  ...econstituting the operation of the tricarboxylic acid cycle and preventing depletion of key metabolites from the mitochondrial matrix. In human skeletal muscle
  7 KB (968 words) - 23:59, 24 April 2024
• Substrate-uncoupler-inhibitor titration
  ...be extended over 1 to 2 hours), highly diluted sample to avoid fast oxygen depletion in the closed chamber, and the possibility for re-oxygenations to extend me |mitopedia topic=Inhibitor, Substrate and metabolite, Uncoupler
  3 KB (339 words) - 08:57, 27 May 2020
• Kamunde 2018 Free Radic Biol Med
  .../sub>O₂ typically present in cells would favor emission of this metabolite but the scavenging systems would prevent its accumulation.
  3 KB (465 words) - 13:30, 7 March 2020
• Petit 2017 MiPschool Obergurgl
  ...which can both hydrolyze acetylpyruvate and decarboxylate oxaloacetate, a metabolite of the tricarboxylic acid (TCA) cycle. FAHD1 is the first described eukaryo ...d HUVEC had a decreased oxygen consumption rate (Figure 1 E). In addition, depletion of FAHD1 in the breast cancer cell line MCF-7 revealed an inhibition of cel
  8 KB (1,147 words) - 14:10, 26 March 2018
• FNS
  ...rgent electron-input into the [[Q-junction]], to compensate for metabolite depletion into the incubation medium. FNS in combination exerts an [[additive effect
  3 KB (403 words) - 19:58, 1 January 2021
• Morad 2016 J Lipid Res
  ...that tamoxifen enhances the ceramide effect by blocking its metabolism. As depletion of ATP and targeting the "Warburg effect" represent dynamic metabolic insul
  3 KB (367 words) - 13:08, 24 February 2020
• Paulus 2022 Basic Res Cardiol
  ...CM. The metabolite profiles of ELVD and TCM were characterised by profound depletion of tricarboxylic acid cycle intermediates. Redox balance was shifted toward
  3 KB (417 words) - 12:29, 26 September 2022
• Chicco 2022 Abstract Bioblast
  ...ion of TCA cycle function in mt-preparations, to compensate for metabolite depletion into the incubation medium. NS in combination exerts an additive effect on
  4 KB (625 words) - 08:33, 28 July 2022
• Gnaiger 2015 Abstract MiPschool Cape Town 2015
  ...apacities. Multiple substrates are supplied to counterbalance intermediary metabolite loss from the mitochondria into the dilute incubation medium. Physiological ...ria, specific inhibitors applied to block selected mt-pathways, metabolite depletion from the mt-matrix, and activities of mt-matrix dehydrogenases. Electron ga
  7 KB (953 words) - 18:33, 10 January 2022

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