From Bioblast
O2k-Publications: Fatty acid
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Year | Reference | Tissue and cell | Cell line | Mammal and model | Nonmammal | |
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Tian 2023 Redox Biol | 2023 | Tian G, Zhou J, Quan Y, Kong Q, Li J, Xin Y, Wu W, Tang X, Liu X (2023) Voltage-dependent anion channel 1 (VDAC1) overexpression alleviates cardiac fibroblast activation in cardiac fibrosis via regulating fatty acid metabolism. https://doi.org/10.1016/j.redox.2023.102907 | Heart Fibroblast | Mouse | ||
Frangos 2023 J Biol Chem | 2023 | Frangos SM, DesOrmeaux GJ, Holloway GP (2023) Acidosis attenuates CPT-I supported bioenergetics as a potential mechanism limiting lipid oxidation. https://doi.org/10.1016/j.jbc.2023.105079 | Skeletal muscle | Mouse | ||
Pereyra 2023 Am J Physiol Gastrointest Liver Physiol | 2023 | Pereyra AS, McLaughlin KL, Buddo KA, Ellis JM (2023) Medium-chain fatty acid oxidation is independent of L-carnitine in liver and kidney but not in heart and skeletal muscle. https://doi.org/10.1152/ajpgi.00105.2023 | Heart Skeletal muscle Liver Kidney | Mouse | ||
Smith 2021 Am J Physiol Endocrinol Metab | 2021 | Smith CD, Lin CT, McMillin SL, Weyrauch LA, Schmidt CA, Smith CA, Kurland IJ, Witczak CA, Neufer PD (2021) Genetically increasing flux through β-oxidation in skeletal muscle increases mitochondrial reductive stress and glucose intolerance. https://doi.org/10.1152/ajpendo.00010.2021 | Skeletal muscle | Mouse | ||
Pereyra 2021 J Lipid Res | 2021 | Pereyra AS, Harris KL, Soepriatna AH, Waterbury QA, Bharathi SS, Zhang Y, Fisher-Wellman KH, Goergen CJ, Goetzman ES, Ellis JM (2021) Octanoate is differentially metabolized in liver and muscle and fails to rescue cardiomyopathy in CPT2 deficiency. J Lipid Res 62:100069. | Heart Skeletal muscle Liver | Mouse | ||
Oemer 2021 J Lipid Res | 2021 | Oemer G, Edenhofer ML, Wohlfarter Y, Lackner K, Leman G, Koch J, Cardoso LHD, Lindner HH, Gnaiger E, Dubrac S, Zschocke J, Keller MA (2021) Fatty acyl availability modulates cardiolipin composition and alters mitochondrial function in HeLa cells. https://doi.org/10.1016/j.jlr.2021.100111 | HeLa | Human | ||
Kakimoto 2021 Redox Biol | 2021 | Kakimoto PA, Serna JDC, de Miranda Ramos V, Zorzano A, Kowaltowski AJ (2021) Increased glycolysis is an early consequence of palmitate lipotoxicity mediated by redox signaling. Redox Biol 45:102026. | Liver | Human | ||
Queiroz 2021 Mol Metab | 2021 | Queiroz AL, Lessard SJ, Ouchida AT, Araujo HN, Goncalves DA, Simoes Froes Guimaraes DSP, Teodoro BG, So K, Espreafico EM, Hirshman MF, Alberici LC, Kettelhut IDC, Goodyear LJ, Silveira LR (2021) The MicroRNA miR-696 is regulated by SNARK and reduces mitochondrial activity in mouse skeletal muscle through Pgc1α inhibition. Mol Metab 51:101226. | Skeletal muscle | Mouse | ||
Aparicio-Trejo 2020 Free Radic Biol Med | 2020 | Aparicio-Trejo OE, Avila-Rojas SH, Tapia E, Rojas-Morales P, León-Contreras JC, Martínez-Klimova E, Hernández-Pando R, Sánchez-Lozada LG, Pedraza-Chaverri J (2020) Chronic impairment of mitochondrial bioenergetics and β-oxidation promotes experimental AKI-to-CKD transition induced by folic acid. Free Radic Biol Med 154:18-32. | Kidney | Rat | ||
Gruenig 2020 Biochem Pharmacol | 2020 | Grünig D, Szabo L, Marbet M, Krähenbühl S (2020) Valproic acid affects fatty acid and triglyceride metabolism in HepaRG cells exposed to fatty acids by different mechanisms. Biochem Pharmacol 177:113860. | Liver | Mouse | ||
Cecatto 2020 Mitochondrion | 2020 | Cecatto C, Amaral AU, Wajner A, Wajner SM, Castilho RF, Wajner M (2020) Disturbance of mitochondrial functions associated with permeability transition pore opening induced by cis-5-tetradecenoic and myristic acids in liver of adolescent rats. Mitochondrion 50:1-13. | Liver Other cell lines | Rat | ||
Cecatto 2020 Toxicol In Vitro | 2020 | Cecatto C, Amaral AU, Roginski AC, Castilho RF, Wajner M (2020) Impairment of mitochondrial bioenergetics and permeability transition induction caused by major long-chain fatty acids accumulating in VLCAD deficiency in skeletal muscle as potential pathomechanisms of myopathy. Toxicol In Vitro 62:104665. | Skeletal muscle | Rat | ||
Maekawa 2019 Cell Commun Signal | 2019 | Maekawa S, Takada S, Nambu H, Furihata T, Kakutani N, Setoyama D, Ueyanagi Y, Kang D, Sabe H, Kinugawa S (2019) Linoleic acid improves assembly of the CII subunit and CIII2/CIV complex of the mitochondrial oxidative phosphorylation system in heart failure. Cell Commun Signal 17:128. | Heart | Mouse | ||
Turnbull 2019 Am J Physiol Cell Physiol | 2019 | Turnbull PC, Hughes MC, Perry CGR (2019) The fatty acid derivative palmitoylcarnitine abrogates colorectal cancer cell survival by depleting glutathione. Am J Physiol Cell Physiol 317:C1278-88. | Endothelial;epithelial;mesothelial cell | Human | ||
Cooper 2019 Exp Physiol | 2019 | Cooper MA, McCoin C, Pei D, Thyfault JP, Koestler D, Wright DE (2019) Reduced mitochondrial reactive oxygen species production in peripheral nerves of mice fed a ketogenic diet. Exp Physiol 103:1206-12. | Nervous system | Mouse | ||
Zhang 2019 Redox Biol | 2019 | Zhang Y, Bharathi SS, Beck ME, Goetzman ES (2019) The fatty acid oxidation enzyme long-chain acyl-CoA dehydrogenase can be a source of mitochondrial hydrogen peroxide. Redox Biol 26:101253. | Liver | Mouse | ||
Oliveira 2019 Mol Nutr Food Res | 2019 | Oliveira TE, Castro É, Belchior T, Andrade ML, Chaves-Filho AB, Peixoto AS, Moreno MF, Ortiz Silva M, Moreira RJ, Inague A, Yoshinaga MY, Miyamoto S, Moustaid-Moussa N, Festuccia WT (2019) Fish oil protects wild type and uncoupling protein 1 deficient mice from obesity and glucose intolerance by increasing energy expenditure. Mol Nutr Food Res 63:e1800813. | Fat | Mouse | ||
Petrick 2019 Biochem J | 2019 | Petrick HL, Holloway GP (2019) High intensity exercise inhibits carnitine palmitoyltransferase-I sensitivity to L-carnitine. Biochem J 476:547-58. | Skeletal muscle | Mouse | ||
Miotto 2018 Thesis | 2018 | Miotto PM (2018) The influence of exercise and high fat feeding on the regulation of mitochondrial substrate sensitivity in skeletal muscle. PhD Thesis p185. | Skeletal muscle | Mouse | ||
Lima 2018 Biochem Cell Biol | 2018 | Lima T, Silveira L (2018) A microplate assay for measuring cell death in C2C12 cells. Biochem Cell Biol 96:702-6. | Skeletal muscle Other cell lines | Mouse | ||
Boutoual 2018 Scientific Reports | 2018 | Boutoual, R., Meseguer, S., Villarroya, M., Martin-Hernandez, E., Errami, M., Martin, M. A., Casado, M., and Armengod, M. E. (2018) Defects in the mitochondrial-tRNA modification enzymes MTO1 and GTPBP3 promote different metabolic reprogramming through a HIF-PPARgamma-UCP2-AMPK axis. Scientific reports 8, 1163 | Other cell lines Fibroblast | Human | ||
Kuehn 2018 Biochem Pharmacol | 2018 | Kühn B, Brat C, Fettel J, Hellmuth N, Maucher IV, Bulut U, Hock KJ, Grimmer J, Manolikakes G, Rühl M, Kühn A, Zacharowski K, Matrone C, Urbschat A, Roos J, Steinhilber D, Maier TJ (2018) Anti-inflammatory nitro-fatty acids suppress tumor growth by triggering mitochondrial dysfunction and activation of the intrinsic apoptotic pathway in colorectal cancer cells. Biochem Pharmacol 155:48-60. | Endothelial;epithelial;mesothelial cell Other cell lines | Human | ||
Rossignoli 2018 J Nutr Biochem | 2018 | Rossignoli CP, Dechandt CRP, Souza AO, Sampaio IH, Vicentini TM, Teodoro BG, Neto MPC, Ferrari GD, Couto-Lima CA, Alberici LC (2018) Effects of intermittent dietary supplementation with conjugated linoleic acid and fish oil (EPA/DHA) on body metabolism and mitochondrial energetics in mice. J Nutr Biochem 60:16-23. | Skeletal muscle Nervous system Liver Fat | Mouse | ||
Cooper 2018 Exp Physiol | 2018 | Cooper MA, McCoin C, Pei D, Thyfault JP, Koestler D, Wright DE (2018) Reduced mitochondrial reactive oxygen species production in peripheral nerves of mice fed a ketogenic diet. Exp Physiol 103:1206-12. | Nervous system | Mouse | ||
Giacco 2018 FASEB J | 2018 | Giacco A, Delli Paoli G, Senese R, Cioffi F, Silvestri E, Moreno M, Ruoppolo M, Caterino M, Costanzo M, Lombardi A, Goglia F, Lanni A, de Lange P (2018) The saturation degree of fatty acids and their derived acylcarnitines determines the direct effect of metabolically active thyroid hormones on insulin sensitivity in skeletal muscle cells. FASEB J 33:1811-23. | Skeletal muscle | Rat | ||
Jelenik 2018 Diabetes | 2018 | Jelenik T, Flögel U, Álvarez-Hernández E, Scheiber D, Zweck E, Ding Z, Rothe M, Mastrototaro L, Kohlhaas V, Kotzka J, Knebel B, Müller-Wieland D, Moellendorf S, Gödecke A, Kelm M, Westenfeld R, Roden M, Szendroedi J (2018) Insulin resistance and vulnerability to cardiac ischemia. Diabetes 67:2695-702. | Heart | Human Mouse | ||
Apostolopoulou 2018 Thesis | 2018 | Apostolopoulou M (2018) Determinants of insulin sensitivity in obesity and recent-onset type 2 diabetes mellitus. PhD Thesis 77. | Liver | Human | ||
Cecatto 2018 FEBS J | 2018 | Cecatto C, Amaral AU, da Silva JC, Wajner A, Schimit MOV, da Silva LHR, Wajner SM, Zanatta A, Castilho RF, Wajner M (2018) Metabolite accumulation in VLCAD deficiency markedly disrupts mitochondrial bioenergetics and Ca2+ homeostasis in the heart. FEBS J 285:1437-55. | Heart Other cell lines | Rat | ||
Kyhl 2017 Peptides | 2017 | Kyhl K, Lønborg J, Hartmann B, Kissow H, Poulsen SS, Ali HE, Kjær A, Dela F, Engstrøm T, Treiman M (2017) Lack of effect of prolonged treatment with liraglutide on cardiac remodeling in rats after acute myocardial infarction. Peptides 93:1-12. | Heart | Rat | ||
Schoenfeld 2017 Neurochem Int | 2017 | Schönfeld P, Reiser G (2017) Brain energy metabolism spurns fatty acids as fuel due to their inherent mitotoxicity and potential capacity to unleash neurodegeneration. Neurochem Int 109:68-77. | Nervous system Liver | Rat | ||
Uppala 2017 Biochem Biophys Res Commun | 2017 | Uppala R, Dudiak B, Beck ME, Bharathi SS, Zhang Y, Stolz DB, Goetzman ES (2017) Aspirin increases mitochondrial fatty acid oxidation. Biochem Biophys Res Commun 482:346-51. | HEK Fibroblast | Human Mouse | ||
Van Schaardenburgh 2016 PLOS ONE | 2016 | van Schaardenburgh M, Wohlwend M, Rognmo Ø, Mattsson EJ (2016) Mitochondrial respiration after one session of calf raise exercise in patients with peripheral vascular disease and healthy older adults. PLOS ONE 11:e0165038. | Skeletal muscle | Human | ||
Liepinsh 2016 Biochem J | 2016 | Liepinsh E, Makrecka-Kuka M, Volska K, Kuka J, Makarova E, Antone U, Sevostjanovs E, Vilskersts R, Strods A, Tars K, Dambrova M (2016) Long-chain acylcarnitines determine ischaemia/reperfusion-induced damage in heart mitochondria. Biochem J 473:1191-202. | Heart | Rat | ||
Schoenfeld 2016 J Cereb Blood Flow Metab | 2016 | Schönfeld P, Reiser G (2016) Inhibition of b-oxidation is not a valid therapeutic tool for reducing oxidative stress in conditions of neurodegeneration. J Cereb Blood Flow Metab 37:848-54. | Nervous system | Rat | ||
Cecatto 2016 Thesis | 2016 | Cecatto C (2016) Efeitos de acidos graxos hidroxilados de cadeia longa acumulados nas deficiencias da 3-hidroxiacil CoA desidrogenase de cadeia longa e da proteina trifunctional mitocondrial sobre a homeostase energetica mitochondrial nos musculos cardiaco e esqueletico de ratos jovens. Dissertation p103. | Heart Skeletal muscle | Rat | ||
Cecatto 2016 Toxicol In Vitro | 2016 | Cecatto C, Godoy KD, da Silva JC, Amaral AU, Wajner M (2016) Disturbance of mitochondrial functions provoked by the major long-chain 3-hydroxylated fatty acids accumulating in MTP and LCHAD deficiencies in skeletal muscle. Toxicol In Vitro 36:1-9. | Skeletal muscle | Rat | ||
Amaral 2016 Biochim Biophys Acta | 2016 | Amaral AU, Cecatto C, da Silva JC, Wajner A, Godoy KD, Ribeiro RT, Wajner M (2016) cis-4-Decenoic and decanoic acids impair mitochondrial energy, redox and Ca2+ homeostasis and induce mitochondrial permeability transition pore opening in rat brain and liver: Possible implications for the pathogenesis of MCAD deficiency. Biochim Biophys Acta 1857:1363-72. | Nervous system Liver | Rat | ||
Peyta 2016 Biochim Biophys Acta | 2016 | Peyta L, Jarnouen K, Pinault M, Guimaraes C, Pais de Barros JP, Chevalier S, Dumas JF, Maillot F, Hatch GM, Loyer P, Servais S (2016) Reduced cardiolipin content decreases respiratory chain capacities and increases ATP synthesis yield in the human HepaRG cells. Biochim Biophys Acta 1857:443-53. | Liver Other cell lines | Human | ||
Ojuka 2016 Am J Physiol Endocrinol Metab | 2016 | Ojuka E, Andrew B, Bezuidenhout N, George S, Maarman G, Madlala HP, Mendham A, Osiki PO (2016) Measurement of β-oxidation capacity of biological samples by respirometry: a review of principles and substrates. Am J Physiol Endocrinol Metab 310:E715-23. https://doi.org/10.1152/ajpendo.00475.2015 | Skeletal muscle Liver | Human Mouse Rat | ||
Van Eunen 2016 BMC Biol | 2016 | van Eunen K, Volker-Touw CM, Gerding A, Bleeker A, Wolters JC, van Rijt WJ, Martines AM, Niezen-Koning KE, Heiner RM, Permentier H, Groen AK, Reijngoud DJ, Derks TG, Bakker BM (2016) Living on the edge: substrate competition explains loss of robustness in mitochondrial fatty-acid oxidation disorders. BMC Biol 14:107. | Liver | Mouse | ||
Sheldon 2015 Am J Physiol Gastrointest Liver Physiol | 2015 | Sheldon RD, Padilla J, Jenkins NT, Laughlin MH, Rector RS (2015) Chronic NOS inhibition accelerates NAFLD progression in an obese rat model. Am J Physiol Gastrointest Liver Physiol 308:G540-9. | Liver | Rat | ||
Hecker 2015 Methods Mol Biol | 2015 | Hecker M, Sommer N, Mayer K (2015) Assessment of short- and medium-chain fatty acids on mitochondrial function in severe Inflammation. Methods Mol Biol 1265:389-96. | Endothelial;epithelial;mesothelial cell | Human | ||
Christiansen 2015 Am J Physiol Heart Circ Physiol | 2015 | Christiansen LB, Dela F, Koch J, Hansen CN, Leifsson PS, Yokota T (2015) Impaired cardiac mitochondrial oxidative phosphorylation and enhanced mitochondrial oxidative stress in feline hypertrophic cardiomyopathy. Am J Physiol Heart Circ Physiol 308:H1237-47. | Heart Skeletal muscle | Cat | ||
Ludzki 2015 Diabetes | 2015 | Ludzki A, Paglialunga S, Smith BK, Herbst EA, Allison MK, Heigenhauser GJ, Neufer PD, Holloway GP (2015) Rapid repression of ADP transport by palmitoyl-CoA is attenuated by exercise training in humans; a potential mechanism to decrease oxidative stress and improve skeletal muscle insulin signaling. Diabetes 64:2769-79. | Skeletal muscle | Human Mouse | ||
Alonso-Vale 2015 FASEB J | 2015 | Alonso-Vale MI, Cruz M, Bolsoni-Lopes A, de Sá R, Bresciani Martins de Andrade P (2015) Palmitoleic acid (C16:1n7) treatment enhances fatty acid oxidation and oxygen consumption in white adipocytes. FASEB J 29:884.25. | Fat | Mouse | ||
Schwarzkopf 2015 Neuroscience | 2015 | Schwarzkopf TM, Koch K, Klein J (2015) Reduced severity of ischemic stroke and improvement of mitochondrial function after dietary treatment with the anaplerotic substance triheptanoin. Neuroscience 300:201-9. | Nervous system | Mouse | ||
Senyilmaz 2015 Nature | 2015 | Senyilmaz D, Virtue S, Xu X, Tan CY, Griffin JL, Miller AK, Vidal-Puig A, Teleman AA (2015) Regulation of mitochondrial morphology and function by stearoylation of TFR1. Nature 525:124-8. | Drosophila | |||
Beaudoin 2014 J Physiol | 2014 | Beaudoin MS, Perry CC, Arkell A, Chabowski A, Simpson JA, Wright DC, Holloway GP (2014) In the ZDF rat, impairments in mitochondrial palmitoyl-CoA respiratory kinetics that precede the development of diabetic cardiomyopathy are prevented by resveratrol supplementation. J Physiol 592:2519-33. | Heart | Rat | ||
Hecker 2014 JPEN | 2014 | Hecker M, Sommer N, Voigtmann H, Pak O, Mohr A, Wolf M, Vadász I, Herold S, Weissmann N, Morty R, Seeger W, Mayer K (2014) Impact of short- and medium-chain fatty acids on mitochondrial function in severe inflammation. J Parenter Enteral Nutr 38:587-94. | Endothelial;epithelial;mesothelial cell Blood cells HUVEC | Human | ||
Lopez-Erauskin 2013 Hum Mol Genet | 2013 | López-Erauskin J, Galino J, Ruiz M, Cuezva JM, Fabregat I, Cacabelos D, Boada J, Martínez J, Ferrer I, Pamplona R, Villarroya F, Portero-Otín M, Fourcade S, Pujol A (2013) Impaired mitochondrial oxidative phosphorylation in the peroxisomal disease X-linked adrenoleukodystrophy. Hum Mol Genet 22:3296-305. | Nervous system | Mouse | ||
Ye 2013 Anal Biochem | 2013 | Ye F, Hoppel CL (2013) Measuring oxidative phosphorylation in human skin fibroblasts. https://doi.org/10.1016/j.ab.2013.02.010 | Skeletal muscle Fibroblast | Human | ||
Yin 2013 Cell Metab | 2013 | Yin H, Pasut A, Soleimani VD, Bentzinger CF, Antoun G, Thorn S, Seale P, Fernando P, van Ijcken W, Grosveld F, Dekemp RA, Boushel RC, Harper ME, Rudnicki MA (2013) MicroRNA-133 controls brown adipose determination in skeletal muscle satellite cells by targeting Prdm16. Cell Metab 17:210-24. | Skeletal muscle Fat | Mouse | ||
Felser 2013 Toxicol Sci | 2013 | Felser A, Blum K, Lindinger PW, Bouitbir J, Kraehenbuehl S (2013) Mechanisms of hepatocellular toxicity associated with dronedarone - a comparison to amiodarone. Toxicol Sci 131:480-90. | Liver | Human Rat | ||
Jaburek 2013 Int J Biochem Cell Biol | 2013 | Jabůrek M, Ježek J, Zelenka J, Ježek P (2013) Antioxidant activity by a synergy of redox-sensitive mitochondrial phospholipase A2 and uncoupling protein-2 in lung and spleen. Int J Biochem Cell Biol 45:816-25. | Mouse | |||
Singh 2013 J Cereb Blood Flow Metab | 2013 | Singh IN, Gilmer LK, Miller DM, Cebak JE, Wang JA, Hall ED (2013) Phenelzine mitochondrial functional preservation and neuroprotection after traumatic brain injury related to scavenging of the lipid peroxidation-derived aldehyde 4-hydroxy-2-nonenal. J Cereb Blood Flow Metab 33:593-9. | Nervous system | Rat | ||
Stride 2013 Eur J Heart Fail | 2013 | Stride N, Larsen S, Hey-Mogensen M, Sander K, Lund JT, Gustafsson F, Kober L, Dela F (2013) Decreased mitochondrial oxidative phosphorylation capacity in the human heart with left ventricular systolic dysfunction. Eur J Heart Fail 15:150-7. | Heart | Human | ||
Lou 2013 Cardiovasc Res | 2013 | Lou PH, Zhang L, Lucchinetti E, Heck M, Affolter A, Gandhi M, Kienesberger PC, Hersberger M, Clanachan AS, Zaugg M (2013) Infarct-remodelled hearts with limited oxidative capacity boost fatty acid oxidation after conditioning against ischaemia/reperfusion injury. Cardiovasc Res 97:251-61. | Heart | Rat | ||
Van Eunen 2013 PLoS Comput Biol | 2013 | van Eunen K, Simons SM, Gerding A, Bleeker A, den Besten G, Touw CM, Houten SM, Groen BK, Krab K, Reijngoud DJ, Bakker BM (2013) Biochemical competition makes fatty-acid β-oxidation vulnerable to substrate overload. PLoS Comput Biol 9:e1003186. | Liver | Rat | ||
Smith 2012 Biochem J | 2012 | Smith BK, Perry CG, Koves TR, Wright DC, Smith JC, Neufer PD, Muoio DM, Holloway GP (2012) Identification of a novel malonyl-CoA IC50 for CPT-I: implications for predicting in vivo fatty acid oxidation rates. Biochem J 448:13-20. | Skeletal muscle | Rat | ||
Pesta 2012 Methods Mol Biol | 2012 | Pesta D, Gnaiger E (2012) High-resolution respirometry. OXPHOS protocols for human cells and permeabilized fibers from small biopsies of human muscle. Methods Mol Biol 810:25-58. https://doi.org/10.1007/978-1-61779-382-0_3 | Skeletal muscle Other cell lines HEK Fibroblast HUVEC | Human | ||
Attane 2012 Diabetes | 2012 | Attané C, Foussal C, Le Gonidec S, Benani A, Daviaud D, Wanecq E, Guzmán-Ruiz R, Dray C, Bezaire V, Rancoule C, Kuba K, Ruiz-Gayo M, Levade T, Penninger J, Burcelin R, Pénicaud L, Valet P, Castan-Laurell I (2012) Apelin treatment increases complete fatty acid oxidation, mitochondrial oxidative capacity, and biogenesis in muscle of insulin-resistant mice. Diabetes 61:310-20. | Skeletal muscle | Mouse | ||
De Meis 2012 Biosci Rep | 2012 | De Meis L, Ketzer LA, Camacho-Pereira J, Galina A (2012) Brown adipose tissue mitochondria: modulation by GDP and fatty acids depends on the respiratory substrates. Biosci Rep 32:53-9. | Fat | Human | ||
McFarlan 2012 J Biol Chem | 2012 | McFarlan JT, Yoshida Y, Jain SS, Han XX, Snook LA, Lally J, Smith BK, Glatz JF, Luiken JJ, Sayer RA, Tupling AR, Chabowski A, Holloway GP, Bonen A (2012) In vivo, fatty acid translocase (CD36) critically regulates skeletal muscle fuel selection, exercise performance and training-induced adaptation of fatty acid oxidation. J Biol Chem 287:23502-16. | Skeletal muscle | Mouse | ||
Hals 2012 Biochem Biophys Res Commun | 2012 | Hals IK, Ogata H, Pettersen E, Ma Z, Björklund A, Skorpen F, Egeberg KW, Grill V (2012) Marked over expression of uncoupling protein-2 in beta cells exerts minor effects on mitochondrial metabolism. Biochem Biophys Res Commun 423:259-64. | Islet cell;pancreas;thymus | |||
Bosma 2012 Histochem Cell Biol | 2012 | Bosma M, Minnaard R, Sparks LM, Schaart G, Losen M, de Baets MH, Duimel H, Kersten S, Bickel PE, Schrauwen P, Hesselink MK (2012) The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria. Histochem Cell Biol 137:205-16. | Skeletal muscle | Human Rat | ||
Moon 2012 J Biol Chem | 2012 | Moon SH, Jenkins CM, Kiebish MA, Sims HF, Mancuso DJ, Gross RW (2012) Genetic ablation of calcium-independent phospholipase A2γ (iPLA2γ) attenuates calcium-induced opening of the mitochondrial permeability transition pore and resultant cytochrome c release. J Biol Chem 287:29837-50. | Liver | Mouse | ||
Lou 2012 Cardiovasc Res | 2012 | Lou PH, Zhang L, Lucchinetti E, Heck M, Affolter A, Gandhi M, Kienesberger PC, Hersberger M, Clanachan AS, Zaugg M (2012) Infarct-remodeled hearts with limited oxidative capacity boost fatty acid oxidation after conditioning against ischemia/reperfusion injury. Cardiovasc Res 97:251-61. | Heart | Rat | ||
Jacobs 2012 J Appl Physiol | 2012 | Jacobs R, Lundby C (2012) Mitochondria express enhanced quality as well as quantity in association with aerobic fitness across recreationally active individuals up to elite athletes. J Appl Physiol 114:344-50. | Skeletal muscle | Human | ||
Hoeks 2011 PLoS One | 2011 | Hoeks J, de Wilde J, Hulshof MF, van den Berg SA, Schaart G, van Dijk KW, Smit E, Mariman EC (2011) High fat diet-induced changes in mouse muscle mitochondrial phospholipids do not impair mitochondrial respiration despite insulin resistance. PLoS One 6:e27274. | Skeletal muscle | Mouse | ||
Lemieux 2011 Int J Biochem Cell Biol | 2011 | Lemieux H, Semsroth S, Antretter H, Höfer D, Gnaiger E (2011) Mitochondrial respiratory control and early defects of oxidative phosphorylation in the failing human heart. Int J Biochem Cell Biol 43:1729–38. https://doi.org/10.1016/j.biocel.2011.08.008 | Heart | Human | ||
Brands 2011 Metabolism | 2011 | Brands M, Hoeks J, Sauerwein HP, Ackermans MT, Ouwens M, Lammers NM, van der Plas MN, Schrauwen P, Groen AK, Serlie MJ (2011) Short-term increase of plasma free fatty acids does not interfere with intrinsic mitochondrial function in healthy young men. Metabolism 60:1398-405. | Skeletal muscle | Human | ||
Nabben 2011 Biochim Biophys Acta | 2011 | Nabben M, Shabalina IG, Moonen-Kornips E, van Beurden D, Cannon B, Schrauwen P, Nedergaard J, Hoeks J (2011) Uncoupled respiration, ROS production, acute lipotoxicity and oxidative damage in isolated skeletal muscle mitochondria from UCP3-ablated mice. Biochim Biophys Acta 1807:1095-105. | Skeletal muscle | Mouse | ||
Pesta 2011 Am J Physiol Regul Integr Comp Physiol | 2011 | Pesta D, Hoppel F, Macek C, Messner H, Faulhaber M, Kobel C, Parson W, Burtscher M, Schocke M, Gnaiger E (2011) Similar qualitative and quantitative changes of mitochondrial respiration following strength and endurance training in normoxia and hypoxia in sedentary humans. Am J Physiol Regul Integr Comp Physiol 301:R1078–87. | Skeletal muscle | Human | ||
Smith 2011 Biochem J | 2011 | Smith BK, Jain SS, Rimbaud S, Dam A, Quadrilatero J, Ventura-Clapier R, Bonen A, Holloway GP (2011) FAT/CD36 is located on the outer mitochondrial membrane, upstream of long-chain acyl-CoA synthetase, and regulates palmitate oxidation. Biochem J 437:125-34. | Skeletal muscle | Mouse | ||
Boyle 2011 Int J Obes | 2011 | Boyle KE, Zheng D, Anderson EJ, Neufer PD, Houmard JA (2011) Mitochondrial lipid oxidation is impaired in cultured myotubes from obese humans. Int J Obes 36:1025-31. | Skeletal muscle | Human | ||
Bartesaghi 2010 Chem Res Toxicol | 2010 | Bartesaghi S, Wenzel J, Trujillo M, López M, Joseph J, Kalyanaraman B, Radi R (2010) Lipid peroxyl radicals mediate tyrosine dimerization and nitration in membranes. Chem Res Toxicol 23:821-35. | ||||
De Meis 2010 PLoS One | 2010 | De Meis L, Ketzer LA, da Costa RM, de Andrade IR, Benchimol M (2010) Fusion of the endoplasmic reticulum and mitochondrial outer membrane in rats brown adipose tissue: activation of thermogenesis by Ca2+. PLoS One 5:e9439. | Fat | Rat | ||
Chowdhury 2010 Am J Physiol Endocrinol Metab | 2010 | Chowdhury SK, Sangle GV, Xie X, Stelmack GL, Halayko AJ, Shen GX (2010) Effects of extensively oxidized low-density lipoprotein on mitochondrial function and reactive oxygen species in porcine aortic endothelial cells. Am J Physiol Endocrinol Metab 298:E89-98. | Endothelial;epithelial;mesothelial cell | Pig | ||
Dikov 2010 Exp Gerontol | 2010 | Dikov D, Aulbach A, Muster B, Dröse S, Jendrach M, Bereiter-Hahn J (2010) Do UCP2 and mild uncoupling improve longevity? Exp Gerontol 45:586-95. | HeLa Fibroblast HUVEC | |||
Schoenfeld 2010 Biochim Biophys Acta | 2010 | Schönfeld P, Wieckowski MR, Lebiedzinska M, Wojtczak L (2010) Mitochondrial fatty acid oxidation and oxidative stress: Lack of reverse electron transfer-associated production of reactive oxygen species. Biochim Biophys Acta 1797:929-38. | Heart | Rat | ||
Kane 2010 Free Radic Biol Med | 2010 | Kane DA, Anderson EJ, Price III JW, Woodlief TL, Lin C-T, Bikman BT, Cortright RN, Neufer PD (2010) Metformin selectively attenuates mitochondrial H2O2 emission without affecting respiratory capacity in skeletal muscle of obese rats. Free Radic Biol Med 49:1082–7. | Skeletal muscle | Rat | ||
Van den Berg 2010 Metabolism | 2010 | van den Berg SA, Nabben M, Bijland S, Voshol PJ, van Klinken JB, Havekes LM, Romijn JA, Hoeks J, Hesselink MK, Schrauwen P, van Dijk KW (2010) High levels of whole-body energy expenditure are associated with a lower coupling of skeletal muscle mitochondria in C57Bl/6 mice. Metabolism 59:1612-8. | Skeletal muscle | Mouse | ||
Stankova 2010 Toxicol In Vitro | 2010 | Staňková P, Kučera O, Lotková H, Roušar T, Endlicher R, Cervinková Z (2010) The toxic effect of thioacetamide on rat liver in vitro. Toxicol In Vitro 24:2097-2103. | Liver | |||
Henique 2010 J Biol Chem | 2010 | Henique C, Mansouri A, Fumey G, Lenoir V, Girard J, Bouillaud F, Prip-Buus C, Cohen I (2010) Increased mitochondrial fatty acid oxidation is sufficient to protect skeletal muscle cells from palmitate-induced apoptosis. J Biol Chem 285:36818-27. | Skeletal muscle Other cell lines | Mouse | ||
Kraunsoee 2010 J Physiol | 2010 | Kraunsøe R, Boushel RC, Hansen CN, Schjerling P, Qvortrup K, Støckel M, Mikines KJ, Dela F (2010) Mitochondrial respiration in subcutaneous and visceral adipose tissue from patients with morbid obesity. J Physiol 588:2023-32. | Fat | Human | ||
Raboel 2009 Metabolism | 2009 | Rabøl R, Svendsen PF, Skovbro M, Boushel RC, Haugaard SB, Schjerling P, Schrauwen P, Hesselink MK, Nilas L, Madsbad S, Dela F (2009) Reduced skeletal muscle mitochondrial respiration and improved glucose metabolism in nondiabetic obese women during a very low calorie dietary intervention leading to rapid weight loss. Metabolism 58:1145-52. | Skeletal muscle | Human | ||
Gupte 2009 Diabetes | 2009 | Gupte AA, Bomhoff GL, Swerdlow RH, Geiger PC (2009) Heat treatment improves glucose tolerance and prevents skeletal muscle insulin resistance in rats fed a high-fat diet. Diabetes 58:567-78. | Skeletal muscle | Rat | ||
Anderson 2009 J Clin Invest | 2009 | Anderson EJ, Lustig ME, Boyle KE, Woodlief TL, Kane DA, Lin C-T, Price JW, Kang L, Rabinovitch PS, Szeto HH, Houmard JA, Cortright RN, Wasserman DH, Neufer PD (2009) Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans. J Clin Invest 119:573-81. | Skeletal muscle | Human Mouse Rat | ||
Anderson 2009 J Am Coll Cardiol | 2009 | Anderson EJ, Kypson AP, Rodriguez E, Anderson CA, Lehr EJ, Neufer PD (2009) Substrate-specific derangements in mitochondrial metabolism and redox balance in the atrium of the type 2 diabetic human heart. J Am Coll Cardiol 54:1891-8. | Heart | Human | ||
Nabben 2008 FEBS Lett | 2008 | Nabben M, Hoeks J, Briedé JJ, Glatz JF, Moonen-Kornips E, Hesselink MK, Schrauwen P (2008) The effect of UCP3 overexpression on mitochondrial ROS production in skeletal muscle of young versus aged mice. FEBS Lett 582:4147-52. | Skeletal muscle | Mouse | ||
Phielix 2008 Physiol Behav | 2008 | Phielix E, Mensink M (2008) Type 2 diabetes mellitus and skeletal muscle metabolic function. Physiol Behav 94:252-8. | Skeletal muscle | |||
Hoeks 2008 FEBS Lett | 2008 | Hoeks J, Briedé JJ, de Vogel J, Schaart G, Nabben M, Moonen-Kornips E, Hesselink MK, Schrauwen P (2008) Mitochondrial function, content and ROS production in rat skeletal muscle: Effect of high-fat feeding. FEBS Lett 582:510-16. | Skeletal muscle | Rat | ||
Hein 2008 Hum Mol Genet | 2008 | Hein S, Schönfeld P, Kahlert S, Reiser G (2008) Toxic effects of X-linked adrenoleukodystrophy-associated, very long chain fatty acids on glial cells and neurons from rat hippocampus in culture. Hum Mol Genet 17:1750-61. | Nervous system | Rat | ||
Cervinkova 2008 Physiol Res | 2008 | Cervinková Z, Rauchová H, Kriváková P, Drahota Z (2008) Inhibition of palmityl carnitine oxidation in rat liver mitochondria by tert-butyl hydroperoxide. Physiol Res 57:133-6. | Liver | |||
Oezen 2005 Hum Mol Genet | 2005 | Oezen I, Rossmanith W, Forss-Petter S, Kemp S, Voigtlander T, Moser-Thier K, Wanders RJA, Bittner RE, Berger J (2005) Accumulation of very long-chain fatty acids does not affect mitochondrial function in adrenoleukodystrophy protein deficiency. Hum Mol Genet 14:1127-37. | Skeletal muscle Nervous system Fibroblast | Human Mouse | ||
Hanley 2005 J Physiol | 2005 | Hanley PJ, Dröse S, Brandt U, Lareau RA, Banerjee AL, Srivastava DK, Banaszak LJ, Barycki JJ, Van Veldhoven PP, Daut J (2005) 5-Hydroxydecanoate is metabolised in mitochondria and creates a rate-limiting bottleneck for beta-oxidation of fatty acids. J Physiol 562:307-18. | Heart Skeletal muscle Liver | Human Rat | ||
Rauchova 2003 Acta Biochim Pol | 2003 | Rauchová H, Drahota Z, Rauch P, Fato R, Lenaz G (2003) Coenzyme Q releases the inhibitory effect of free fatty acids on mitochondrial glycerophosphate dehydrogenase. Acta Biochim Pol 50:405-13. | Fat | Other mammals |
O2k-Publications: Fatty acid - Abstracts
Sort in ascending/descending order by a click on one of the small symbols in squares below.
Year | Reference | Tissue and cell | Cell line | Mammal and model | Nonmammal | |
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Komlodi 2023 EUROMIT2023 Bologna | 2023 | Komlódi T, Silva FSG, Duarte AI, Mena D, Garcia-Souza LF, Makrecka-Kuka M, Bento G, Grilo LF, Oliveira PJ, Gnaiger E (2023) Off-target effects of etomoxir: inhibition of mitochondrial Complex I and fatty acid oxidation. EUROMIT2023 International Conference on Mitochondrial Pathology. | Nervous system Liver | Human Mouse | ||
Cecatto 2023 BPS2023 San Diego | 2023 | Cecatto C, Schmitt Sabine, Cardoso L, Videja M, Dambrova M, Makrecka-Kuka M, Liepinsh E, Gnaiger E (2023) Contribution of fatty acid oxidation to respiratory control in brain mitochondria. 67th Annual Meeting of the Biophysical Society. | Heart Nervous system Kidney | Mouse | ||
Cardoso 2023 BPS2023 San Diego | 2023 | Cardoso LHD, Timon-Gomez A, Doerrier C, Garcia-Souza LF, Gnaiger Erich (2023) Respirometric substrate-uncoupler-inhibitor titration protocols for carbohydrate and fatty acid metabolism: from heart to brain mitochondria. 67th Annual Meeting of the Biophysical Society. | Heart Nervous system | |||
Gao 2019 MiPschool Coimbra | 2019 | Effects on mitochondrial respiration of N-acyl amino acids versus common fatty acids. | Skeletal muscle | Rat | ||
Doerrier 2018 MiP2018b | 2018 | Evaluation of anaplerotic pathways to avoid artefacts in respirometric measurement of fatty acid oxidation. | Heart Nervous system Blood cells HEK Platelet | Human Mouse | ||
Wuest 2018 MiPschool Tromso D3 | 2018 | Metabolic flexibility and mitochondrial function in the diabetic heart. | Heart | Pig Mouse Rat | ||
Boardman 2018 MiPschool Tromso D3 | 2018 | High fat-load induces cardioprotection in hearts from obese mice. | Heart | Mouse | ||
Blindheim 2018 IOC134 | 2018 | Bioactive lipophilic substances and their effect on neuronal cells. | Nervous system | |||
Makrecka-Kuka 2018 MiPschool Tromso E1 | 2018 | Cardiac fatty acid oxidation: from in vitro to in vivo. | Heart | |||
Volska 2018 MiP2018 | 2018 | The mechanisms of long-chain acylcarnitine accumulation during ischemia. | Heart | |||
Keller 2018 MiP2018 | 2018 | The structural molecular diversity of mitochondrial cardiolipins. | Heart Nervous system | Mouse | ||
Sobotka 2016 Abstract IOC116 | 2016 | Sobotka O, Kucera Otto, Stankova P, Endlicher R, Nozickova K, Banni A, Cervinkova Z (2016) Mitochondrial respiration in fatty liver. Mitochondr Physiol Network 21.11 | Liver | Rat | ||
Bresciani Martins de Andrade 2014 Abstract MiP2014 | 2014 | Mitochondrial function in white adipose tissue: palmitoleic acid (C16:1n7) treatment enhances white adipocyte oxygen consumption. | Fat | |||
Jaburek 2014 Abstract MiP2014 | 2014 | The role of phospholipase A2γ in the regulation of mitochondrial uncoupling protein 2–dependent antioxidant function. | Islet cell;pancreas;thymus | |||
Nagy 2014 Abstract MiP2014 | 2014 | Investigation of the energy metabolism of microglial cells. | Nervous system | Human | ||
Amoedo 2014 Abstract MiP2014 | 2014 | The metabolic panorama during tumor progression towards malignancy. | Other cell lines | |||
Alberici 2014 Abstract MiP2014 | 2014 | Effects of long-chain acyl-CoA synthetase 6 knockdown in primary skeletal muscle cells metabolism. | Skeletal muscle | Rat | ||
Gnaiger 2013 Abstract ASMRM | 2013 | Gnaiger E(2013) Loss of mitochondrial competence and degenerative disease: cause and effect. Abstract ASMRM-Seoul. | Human | |||
Chicco 2013 Abstract IOC79 | 2013 | Chicco AJ (2013) Substrate-specific impairment of oxidative phosphorylation in Tafazzin-deficient cardiac mitochondria: potential role of CoA deficiency. Mitochondr Physiol Network 18.07 | Heart | Mouse | ||
Jezek 2013 Abstract MiP2013 | 2013 | Ježek P, Ježek J, Zelenka J, Dlasková A, Jabůrek M (2013) Antioxidant synergy of mitochondrial uncoupling protein UCP2 and phospholipase iPLA2γ. Mitochondr Physiol Network 18.08. | Lung;gill Islet cell;pancreas;thymus | Mouse | ||
Kallijarvi 2013 Abstract IOC75 | 2013 | Kallijarvi J (2013) Respiratory chain dysfunction in the Complex III assembly disorder GRACILE. Mitochondr Physiol Network 18.03. | Liver Kidney Fibroblast | Human Mouse | ||
Chicco 2012 Abstract Bioblast | 2012 | Chicco AJ (2012) Substrate-specific impairment of cardiac mitochondrial respiration in Taz-deficient mice: Insight into the pathogenesis of Barth Syndrome. Mitochondr Physiol Network 17.12. | Heart | Mouse | ||
Jacobs 2012 Abstract Bioblast | 2012 | Jacobs R, Lundby C (2012) Mitochondria express enhanced quality as well as quantity in parallel with aerobic fitness across recreationally active individuals up to elite athletes. Mitochondr Physiol Network 17.12. | Skeletal muscle | Human | ||
Watala 2012 Abstract Bioblast | 2012 | Watala C, Przygodzki T, Siewiera K, Kassassir H, Talar M, Labieniec-Watala M (2012) Oxygen consumption in resting and activated blood platelets: platelet mitochondria and cyclooxygenases as compounding targets for high-resolution respirometry. Mitochondr Physiol Network 17.12. | Endothelial;epithelial;mesothelial cell Blood cells Platelet | Human Rat | ||
Le 2012 Abstract Bioblast | 2012 | Le CH, Hocker AD, Dreyer HC, Roach RC, Gnaiger E, Chicco AJ (2012) Two-week acclimatization to 5200m markedly alters substrate utilization and increases OXPHOS efficiency, with no effect on respiratory capacity in skeletal muscle mitochondria. Mitochondr Physiol Network 17.12. | Skeletal muscle | Human | ||
Hoppel 2012 Abstract Bioblast | 2012 | Hoppel CL (2012) Mitochondrial functional testing – muscle biopsy, isolated mitochondria and others. Mitochondr Physiol Network 17.12. | Skeletal muscle Liver | Human | ||
Lund 2012 Abstract IOC68 | 2012 | Lund J, Hafstad AD, Hagve M, Larsen TS, Aasum E (2012) High intensity exercise prevents impairment of respiratory capacity in cardiac mitochondria from obese mice. MiPNet17.08. | Heart | Mouse | ||
Gnaiger 2011 Abstract SMRM-Hyderabad | 2011 | Gnaiger E, Wright-Paradis C, Sondergaard H, Calbet J, Damsgaard R, Munck-Andersen T, Saltin B, Boushel RC (2011) Conserved mitochondrial coupling and adaptive substrate control in Inuit and Caucasians: Acclimatization to active life styles in the Arctic winter. Abstract SMRM-Hyderabad. | Human | |||
Dela MiP2010 | 2010 | Kraunsoee R, Boushel RC, Hansen CN, Schjerling P, Qvortrup K, Stoecke M, Mikines KJ, Dela F (2010) Mitochondrial respiration in subcutaneous and visceral adipose tissue from patients with morbid obesity. Mitochondr Physiol Network 15.6:50-1. | Human | |||
Pesta 2010 Abstract IOC60 | 2010 | Pesta D, Macek C, Hoppel F, Faulhaber M, Burtscher M, Gnaiger E, Schocke M (2010) The impact of endurance training on muscle oxidative capacity. MiPNet15.10. | Human |