Difference between revisions of "MitoEAGLE data: muscle"
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:::: The aim of WG2 will be to provide access to complete data sets for post-study statistical analysis and use harmonization tools (WG1) for standardized documentation, to initiate a data repository on muscle tissue from humans and model organisms in health and disease. Data sets shall be obtained from already published and new studies, prompting participating labs to report experimental details beyond those already published as far as possible (using tools such as PubMed Commons). As a result, specific protocols will be summarized for handling muscle tissue. Depending on specific interests, WG2 may decide to extend their focus to other tissue types. | :::: The aim of WG2 will be to provide access to complete data sets for post-study statistical analysis and use harmonization tools (WG1) for standardized documentation, to initiate a data repository on muscle tissue from humans and model organisms in health and disease. Data sets shall be obtained from already published and new studies, prompting participating labs to report experimental details beyond those already published as far as possible (using tools such as PubMed Commons). As a result, specific protocols will be summarized for handling muscle tissue. Depending on specific interests, WG2 may decide to extend their focus to other tissue types. | ||
== WG2 Participants == | |||
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== WG2 Management == | |||
=== Tasks === | === Tasks === |
Revision as of 14:52, 27 April 2016
News and Events | Working Groups | Short-Term Scientific Missions | Management Committee | Members |
COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping
MitoEAGLE data: muscle
WG2
- MITOEAGLE data repository in muscle and other tissues
WG2 Description
- During the past 10 years, a dramatically increasing number of studies report respirometric data on human muscle tissue (e.g. Christiansen 2015 Am J Physiol). Muscle mitochondrial function is particularly studied in genetically engineered mouse models of human diseases (e.g. Jelenik 2014 Diabetes). However, despite the many published data, lack of consistency often precludes quantitative comparison among data sets with permeabilized or homogenized muscle fibres or isolated mitochondria, normalized to either tissue wet weight, dry weight, protein content, citrate synthase activity or other mitochondrial markers. In the absence of validated conversion factors, these data remain largely unconnected and can only be qualitatively linked.
- The aim of WG2 will be to provide access to complete data sets for post-study statistical analysis and use harmonization tools (WG1) for standardized documentation, to initiate a data repository on muscle tissue from humans and model organisms in health and disease. Data sets shall be obtained from already published and new studies, prompting participating labs to report experimental details beyond those already published as far as possible (using tools such as PubMed Commons). As a result, specific protocols will be summarized for handling muscle tissue. Depending on specific interests, WG2 may decide to extend their focus to other tissue types.
WG2 Participants
Country | City | Contact |
---|---|---|
Australia | Melbourne | Bishop David J |
Austria | Innsbruck | Doerrier Carolina |
Austria | Innsbruck | Laner Verena |
Austria | Innsbruck | Gnaiger Erich |
Austria | Salzburg | Mayr JA |
Belgium | Liege | Votion Dominique-Marie |
Belgium | Leuven | Bird Matthew |
Brazil | São Paulo | Ferreira Julio Cesar B |
Brazil | Jaboticabal, SP | Garcia Geovana S |
Canada | Antigonish | Kane Daniel A |
Canada | Rimouski | Blier Pierre U |
Canada | Rimouski | Vandermeeren E |
Canada | Vancouver | Boushel Robert C |
Canada | Edmonton (Alberta) | Lemieux Helene |
Croatia | Zagreb | Saric A |
Croatia | Split | Mihanovic I |
Czech Republic | Prague | Elkalaf Moustafa |
Czech Republic | Pilsen | Kuncova J |
Czech Republic | Hradec Králové | Waldauf P |
Czech Republic | Pilsen | Markova Michaela |
Czech Republic | Prague 10 | Krajcova Adela |
Denmark | Copenhagen | Gonzalez-Franquesa Alba |
Denmark | Malov | Hey-Mogensen M |
Denmark | Hvidovre | Nehlin Jan O |
Denmark | Copenhagen N | Mortensen OH |
Denmark | Copenhagen | Dela Flemming |
Denmark | Copenhagen | Larsen Steen |
Estonia | Tallinn | Tepp Kersti |
Estonia | Tallinn | Vendelin Marko |
Estonia | Tallinn | Aid-Vanakova Jekaterina |
Estonia | Tallinn | Karro N |
Estonia | Tallinn | Puurand Marju |
Estonia | Tartu | Paju Kalju |
Estonia | Tallinn | Truu Laura |
Estonia | Tallinn | Kaambre Tuuli |
Finland | Helsinki | Pirinen E |
Finland | Jyvaeskylae | Lehti Maarit |
France | Paris | Ventura-Clapier R |
France | Grenoble cedex 9 | Dubouchaud Herve |
France | Montpellier | Cortade F |
France | Bordeaux cedex | Mourier A |
France | Paris | Armand Anne-Sophie |
France | Grenoble Cedex 9 | Schlattner Uwe |
France | Paris | Petit Patrice X |
France | Montpellier Cedex 1 | Chabi Beatrice |
Germany | Rostock | Haider F |
Germany | Bremerhaven | Mark Felix Christopher |
Germany | Nuthetal | Klaus S |
Germany | Munich | Jastroch M |
Germany | Bochum | Platen P |
Germany | Düsseldorf | Granata Cesare |
Germany | Duesseldorf | Roden Michael |
Germany | Duesseldorf | Jelenik T |
Germany | Köln | Kimoloi Sammy |
Germany | Leipzig | Ost Mario |
Germany | Cologne | Pesta Dominik |
Greece | Heraklion | Tavernarakis Nektarios |
Greece | Heraklio | Sidiropoulou K |
Greece | Athens | Trougakos Ioannis P |
India | Haryana | Sharma Vipin |
Ireland | Dublin | O'Gorman Donal |
Ireland | Dublin | Porter Richard K |
Ireland | Sligo | Murphy J |
Israel | Jerusalem | Saada Reisch Ann |
Israel | Rishon Le Zion | Hachmo Yafit |
Israel | Zrifin | Sova Marina |
Italia | Udine | Salvadego Desy |
Italy | Rome | Scatena Roberto |
Italy | Pisa | Gastaldelli Amalia |
Italy | Novara | Reano Simone |
Italy | Milan | De Palma Clara |
Italy | Milan | Giovarelli Matteo |
Italy | Bologna | Genova Maria Luisa |
Japan | Sapporo | Maekawa S |
Japan | Sapporo | Shirakawa R |
Japan | Sapporo | Nambu H |
Latvia | Riga | Kuka Janis |
Latvia | Riga | Zvejniece Liga |
Latvia | Riga | Liepins Edgars |
Latvia | Riga | Inashkina I |
Luxembourg | Strassen | Devaux Yvan |
Malta | Msida | Vella Joanna |
Netherlands | Maastricht | Van Polanen N |
Netherlands | BT Amsterdam | Jaspers Richard T |
Netherlands | Maastricht | Hoeks Joris |
Netherlands | Amsterdam | De Goede Paul |
Netherlands | Maastricht | Grevendonk L |
Netherlands | Wageningen | Keijer Jaap |
Niederlande | ER Masstricht | De Wit-Verheggen V |
Niederlande | ER Masstricht | De Theije C |
Norway | Tromsoe | Larsen Terje S |
Norway | Tromsoe | Aasum E |
Norway | Tromsoe | Schots Pauke C |
Norway | Ullevål | Heiestad Christina |
Norway | Oslo | Lund Jenny |
Norway | Oslo | Nikolic N |
Norway | Oslo | Torp May-Kristin |
Norway | Oslo | Rustan AC |
Norway | Oslo | Eide L |
Norway | Bergen | Tronstad Karl Johan |
Norway | Tromsoe | Jansen Kirsten M |
Poland | Warsaw | Sek Aleksandra |
Poland | Warsaw | Dymkowska Dorota |
Poland | Warsaw | Kampa Rafal Pawel |
Poland | Lodz | Watala Cezary |
Poland | Lodz | Labieniec-Watala Magdalena |
Portugal | Porto | Beleza Jorge |
Portugal | Cantanhede | Martins Joao D |
Portugal | Coimbra | Palmeira Carlos |
Portugal | Coimbra | Martins Marques T |
Portugal | Cantanhede | Ferreira LL |
Portugal | Porto | Coxito Pedro |
Portugal | Coimbra | Carvalho Eugenia |
Portugal | Porto | Magalhaes Jose |
Portugal | Coimbra | Pereira Susana P |
Romania | Timisoara | Lighezan R |
Romania | Timisoara | Muntean Danina M |
Singapore | Singapore | Hausenloy Derek J |
Slovakia | Bratislava | Maderova D |
Slovakia | Bratislava | Nemec Michal |
Slovakia | Bratislava | Ukropec J |
Slovakia | Bratislava | Sumbalova Zuzana |
Slovakia | Bratislava | Ukropcova B |
Slovenia | Ljubljana | Pirkmajer Sergej |
Slovenia | Ljubljana | Dolinar K |
Slovenia | Ljubljana | Mars T |
South Africa | Smith James | |
Spain | Madrid | Moran M |
Spain | Barcelona | Sebastian D |
Spain | Barcelona | Zorzano Antonio |
Spain | Barcelona | Catalan M |
Spain | Armilla (Granada) | Acuna-Castroviejo Dario |
Spain | Barcelona | De la Torre Lara J |
Spain | Sevilla | Bustos Matilde |
Spain | Barcelona | Gama Perez Pau |
Spain | Armilla, Granada | Escames Germaine |
Spain | A Coruña | Blanco FJ |
Spain | Barcelona | Batlle M |
Spain | Armilla (Granada) | Fernandez-Ortiz Marisol |
Spain | Barcelona | Guitart M |
Spain | Barcelona | Garcia-Roves Pablo Miguel |
Spain | Granada | Lopez Garcia Luis Carlos |
Spain | Madrid | Cadenas S |
Sweden | Linköping | Fontes-Oliveira CC |
Sweden | Stockholm | Cardinale Daniele A |
Switzerland | Lausanne | Gebara E |
Switzerland | Lausanne | Morato Fornaguera L |
Switzerland | Lausanne | Sandi Carmen |
Switzerland | Lausanne | Weger M |
Switzerland | Bern | Nuoffer Jean-Marc |
Switzerland | Lausanne | Zalachoras I |
The Netherlands | Wageningen | Van der Ende Miranda |
The Netherlands | BT Amsterdam | Wuest Rob CI |
Turkey | Ankara | Tuncay Erkan |
USA | Fort Collins | Chicco Adam J |
USA | Chicago | Dayanidhi Sudarshan |
USA | Fairbanks | O'Brien Kristin |
USA | Colorado Springs | Jacobs RA |
USA | Norfolk | Lai Nicola |
USA | Baltimore | Gonzalez-Freire Marta |
USA | Seattle | Marcinek DJ |
USA | College Station | White-Springer Sarah H |
USA | Gainesville | Hepple Russell T |
USA | Baltimore | Fang Evandro F |
USA | Orlando | Distefano Giovanna |
USA | Ann Arbor | Beard Daniel A |
USA | Little Rock | Porter Craig |
USA | St Louis | Welch R |
USA | Gainesville | Wohlgemuth Stephanie E |
USA | Gainesville | Neyroud D |
USA | College Station | Latham C |
USA | Boca Raton | Khamoui Andy V |
USA | Baton Rouge | Irving Brian A |
USA | Orlando | Coen Paul M |
USA | Baton Rouge | Axelrod Christopher L |
USA | Torrance | Rossiter Harry B |
United Kingdom | Birmingham | Thakker A |
United Kingdom | Leeds | Boyle JP |
United Kingdom | Nottingham | Chakrabarti Lisa |
United Kingdom | Loughborough | Ebanks Brad |
United Kingdom | Birmingham | Ashcroft S |
United Kingdom | Plymouth, Devon | McKenna Helen T |
United Kingdom | Birmingham | Garten Antje |
United Kingdom | Oxford | Makrecka-Kuka Marina |
United Kingdom | Cambridge | Shiroma Jonathan G |
United Kingdom | Brighton | Moore Anthony L |
United Kingdom | Birmingham | Joanisse S |
United Kingdom | Cambridge | Murray Andrew James |
United Kingdom | London | Szabadkai Gyorgy |
United Kingdom | Manchester | Giakoumaki I |
United States | Providence | Siamwala J |
WG2 Management
Tasks
- Call for participating labs to deliver relevant experimental data on already published studies and to report them in a standardized format.
- Collection and indexing of the data sets as required for statistical analysis.
- Discussion of procedures, protocols and general guidelines.
- Draft a comprehensive review on mt-function in muscle tissue (registration at PROSPERO, link with EQUATOR).
- Opening of the database to the research public for data search and moderated entry of new data sets.
Milestones
- Call for data report delivered.
- Data sets entered in standardized format.
- Summary, interpretation and discussion of data for review.
Deliverables
- A MITOEAGLE database on muscle tissue from humans and model organisms.
- A set of guidelines for future studies on mitochondrial bioenergetics in muscle tissue.
- Draft of review manuscript.
Projects in progress
- » MiPMap