Difference between revisions of "MitoEAGLE data: muscle"
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Revision as of 14:59, 27 April 2016
News and Events | Working Groups | Short-Term Scientific Missions | Management Committee | Members |
COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping
MitoEAGLE data: muscle
WG2
- MITOEAGLE data repository in muscle and other tissues
WG2 Description
- During the past 10 years, a dramatically increasing number of studies report respirometric data on human muscle tissue (e.g. Christiansen 2015 Am J Physiol). Muscle mitochondrial function is particularly studied in genetically engineered mouse models of human diseases (e.g. Jelenik 2014 Diabetes). However, despite the many published data, lack of consistency often precludes quantitative comparison among data sets with permeabilized or homogenized muscle fibres or isolated mitochondria, normalized to either tissue wet weight, dry weight, protein content, citrate synthase activity or other mitochondrial markers. In the absence of validated conversion factors, these data remain largely unconnected and can only be qualitatively linked.
- The aim of WG2 will be to provide access to complete data sets for post-study statistical analysis and use harmonization tools (WG1) for standardized documentation, to initiate a data repository on muscle tissue from humans and model organisms in health and disease. Data sets shall be obtained from already published and new studies, prompting participating labs to report experimental details beyond those already published as far as possible (using tools such as PubMed Commons). As a result, specific protocols will be summarized for handling muscle tissue. Depending on specific interests, WG2 may decide to extend their focus to other tissue types.
WG2 Participants
Country | City | Contact |
---|---|---|
Australia | Melbourne | Bishop David J |
Austria | Salzburg | Mayr JA |
Austria | Innsbruck | Doerrier Carolina |
Austria | Innsbruck | Laner Verena |
Austria | Innsbruck | Gnaiger Erich |
Belgium | Liege | Votion Dominique-Marie |
Belgium | Leuven | Bird Matthew |
Brazil | São Paulo | Ferreira Julio Cesar B |
Brazil | Jaboticabal, SP | Garcia Geovana S |
Canada | Antigonish | Kane Daniel A |
Canada | Rimouski | Blier Pierre U |
Canada | Vancouver | Boushel Robert C |
Canada | Rimouski | Vandermeeren E |
Canada | Edmonton (Alberta) | Lemieux Helene |
Croatia | Zagreb | Saric A |
Croatia | Split | Mihanovic I |
Czech Republic | Prague | Elkalaf Moustafa |
Czech Republic | Pilsen | Kuncova J |
Czech Republic | Hradec Králové | Waldauf P |
Czech Republic | Pilsen | Markova Michaela |
Czech Republic | Prague 10 | Krajcova Adela |
Denmark | Copenhagen | Gonzalez-Franquesa Alba |
Denmark | Malov | Hey-Mogensen M |
Denmark | Copenhagen | Dela Flemming |
Denmark | Hvidovre | Nehlin Jan O |
Denmark | Copenhagen | Larsen Steen |
Denmark | Copenhagen N | Mortensen OH |
Estonia | Tallinn | Kaambre Tuuli |
Estonia | Tallinn | Vendelin Marko |
Estonia | Tallinn | Tepp Kersti |
Estonia | Tallinn | Puurand Marju |
Estonia | Tallinn | Aid-Vanakova Jekaterina |
Estonia | Tallinn | Karro N |
Estonia | Tallinn | Truu Laura |
Estonia | Tartu | Paju Kalju |
Finland | Helsinki | Pirinen E |
Finland | Jyvaeskylae | Lehti Maarit |
France | Paris | Petit Patrice X |
France | Montpellier Cedex 1 | Chabi Beatrice |
France | Paris | Ventura-Clapier R |
France | Grenoble cedex 9 | Dubouchaud Herve |
France | Montpellier | Cortade F |
France | Bordeaux cedex | Mourier A |
France | Grenoble Cedex 9 | Schlattner Uwe |
France | Paris | Armand Anne-Sophie |
Germany | Rostock | Haider F |
Germany | Cologne | Pesta Dominik |
Germany | Nuthetal | Klaus S |
Germany | Bremerhaven | Mark Felix Christopher |
Germany | Munich | Jastroch M |
Germany | Bochum | Platen P |
Germany | Düsseldorf | Granata Cesare |
Germany | Duesseldorf | Jelenik T |
Germany | Duesseldorf | Roden Michael |
Germany | Leipzig | Ost Mario |
Germany | Köln | Kimoloi Sammy |
Greece | Heraklio | Sidiropoulou K |
Greece | Athens | Trougakos Ioannis P |
Greece | Heraklion | Tavernarakis Nektarios |
India | Haryana | Sharma Vipin |
Ireland | Dublin | O'Gorman Donal |
Ireland | Dublin | Porter Richard K |
Ireland | Sligo | Murphy J |
Israel | Zrifin | Sova Marina |
Israel | Jerusalem | Saada Reisch Ann |
Israel | Rishon Le Zion | Hachmo Yafit |
Italia | Udine | Salvadego Desy |
Italy | Rome | Scatena Roberto |
Italy | Pisa | Gastaldelli Amalia |
Italy | Milan | De Palma Clara |
Italy | Novara | Reano Simone |
Italy | Milan | Giovarelli Matteo |
Italy | Bologna | Genova Maria Luisa |
Japan | Sapporo | Maekawa S |
Japan | Sapporo | Shirakawa R |
Japan | Sapporo | Nambu H |
Latvia | Riga | Kuka Janis |
Latvia | Riga | Zvejniece Liga |
Latvia | Riga | Liepins Edgars |
Latvia | Riga | Inashkina I |
Luxembourg | Strassen | Devaux Yvan |
Malta | Msida | Vella Joanna |
Netherlands | Maastricht | Van Polanen N |
Netherlands | Wageningen | Keijer Jaap |
Netherlands | BT Amsterdam | Jaspers Richard T |
Netherlands | Maastricht | Grevendonk L |
Netherlands | Amsterdam | De Goede Paul |
Netherlands | Maastricht | Hoeks Joris |
Niederlande | ER Masstricht | De Wit-Verheggen V |
Niederlande | ER Masstricht | De Theije C |
Norway | Oslo | Eide L |
Norway | Tromsoe | Jansen Kirsten M |
Norway | Tromsoe | Larsen Terje S |
Norway | Tromsoe | Aasum E |
Norway | Tromsoe | Schots Pauke C |
Norway | Oslo | Nikolic N |
Norway | Ullevål | Heiestad Christina |
Norway | Oslo | Lund Jenny |
Norway | Oslo | Rustan AC |
Norway | Oslo | Torp May-Kristin |
Norway | Bergen | Tronstad Karl Johan |
Poland | Warsaw | Sek Aleksandra |
Poland | Warsaw | Kampa Rafal Pawel |
Poland | Warsaw | Dymkowska Dorota |
Poland | Lodz | Watala Cezary |
Poland | Lodz | Labieniec-Watala Magdalena |
Portugal | Coimbra | Palmeira Carlos |
Portugal | Porto | Beleza Jorge |
Portugal | Cantanhede | Martins Joao D |
Portugal | Cantanhede | Ferreira LL |
Portugal | Coimbra | Carvalho Eugenia |
Portugal | Coimbra | Martins Marques T |
Portugal | Porto | Coxito Pedro |
Portugal | Porto | Magalhaes Jose |
Portugal | Coimbra | Pereira Susana P |
Romania | Timisoara | Lighezan R |
Romania | Timisoara | Muntean Danina M |
Singapore | Singapore | Hausenloy Derek J |
Slovakia | Bratislava | Maderova D |
Slovakia | Bratislava | Nemec Michal |
Slovakia | Bratislava | Ukropec J |
Slovakia | Bratislava | Sumbalova Zuzana |
Slovakia | Bratislava | Ukropcova B |
Slovenia | Ljubljana | Pirkmajer Sergej |
Slovenia | Ljubljana | Dolinar K |
Slovenia | Ljubljana | Mars T |
South Africa | Smith James | |
Spain | Madrid | Moran M |
Spain | Barcelona | Garcia-Roves Pablo Miguel |
Spain | Barcelona | Sebastian D |
Spain | Madrid | Cadenas S |
Spain | Barcelona | Catalan M |
Spain | Barcelona | Zorzano Antonio |
Spain | Barcelona | Gama Perez Pau |
Spain | Armilla (Granada) | Acuna-Castroviejo Dario |
Spain | A Coruña | Blanco FJ |
Spain | Barcelona | De la Torre Lara J |
Spain | Sevilla | Bustos Matilde |
Spain | Barcelona | Guitart M |
Spain | Armilla, Granada | Escames Germaine |
Spain | Barcelona | Batlle M |
Spain | Armilla (Granada) | Fernandez-Ortiz Marisol |
Spain | Granada | Lopez Garcia Luis Carlos |
Sweden | Linköping | Fontes-Oliveira CC |
Sweden | Stockholm | Cardinale Daniele A |
Switzerland | Bern | Nuoffer Jean-Marc |
Switzerland | Lausanne | Gebara E |
Switzerland | Lausanne | Morato Fornaguera L |
Switzerland | Lausanne | Sandi Carmen |
Switzerland | Lausanne | Weger M |
Switzerland | Lausanne | Zalachoras I |
The Netherlands | Wageningen | Van der Ende Miranda |
The Netherlands | BT Amsterdam | Wuest Rob CI |
Turkey | Ankara | Tuncay Erkan |
USA | Fort Collins | Chicco Adam J |
USA | Baton Rouge | Irving Brian A |
USA | Baton Rouge | Axelrod Christopher L |
USA | Chicago | Dayanidhi Sudarshan |
USA | Baltimore | Fang Evandro F |
USA | Fairbanks | O'Brien Kristin |
USA | Colorado Springs | Jacobs RA |
USA | Ann Arbor | Beard Daniel A |
USA | Baltimore | Gonzalez-Freire Marta |
USA | Norfolk | Lai Nicola |
USA | College Station | White-Springer Sarah H |
USA | Gainesville | Hepple Russell T |
USA | Orlando | Distefano Giovanna |
USA | St Louis | Welch R |
USA | College Station | Latham C |
USA | Gainesville | Neyroud D |
USA | Little Rock | Porter Craig |
USA | Orlando | Coen Paul M |
USA | Gainesville | Wohlgemuth Stephanie E |
USA | Torrance | Rossiter Harry B |
USA | Boca Raton | Khamoui Andy V |
United Kingdom | Birmingham | Garten Antje |
United Kingdom | Birmingham | Thakker A |
United Kingdom | Manchester | Giakoumaki I |
United Kingdom | Nottingham | Chakrabarti Lisa |
United Kingdom | Birmingham | Ashcroft S |
United Kingdom | Leeds | Boyle JP |
United Kingdom | Oxford | Makrecka-Kuka Marina |
United Kingdom | Loughborough | Ebanks Brad |
United Kingdom | Plymouth, Devon | McKenna Helen T |
United Kingdom | Birmingham | Joanisse S |
United Kingdom | Cambridge | Shiroma Jonathan G |
United Kingdom | Brighton | Moore Anthony L |
United Kingdom | Cambridge | Murray Andrew James |
United Kingdom | London | Szabadkai Gyorgy |
United States | Providence | Siamwala J |
WG2 Management
Tasks
- Call for participating labs to deliver relevant experimental data on already published studies and to report them in a standardized format.
- Collection and indexing of the data sets as required for statistical analysis.
- Discussion of procedures, protocols and general guidelines.
- Draft a comprehensive review on mt-function in muscle tissue (registration at PROSPERO, link with EQUATOR).
- Opening of the database to the research public for data search and moderated entry of new data sets.
Milestones
- Call for data report delivered.
- Data sets entered in standardized format.
- Summary, interpretation and discussion of data for review.
Deliverables
- A MITOEAGLE database on muscle tissue from humans and model organisms.
- A set of guidelines for future studies on mitochondrial bioenergetics in muscle tissue.
- Draft of review manuscript.
Projects in progress
- » MiPMap