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SUIT-018 O2 mt D054

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high-resolution terminology - matching measurements at high-resolution


SUIT-018 O2 mt D054

Description

1GMS;2D;3Ama.png

Abbreviation: NS(GM)

Reference: B: SUIT-018

SUIT number: D054_1GMS;2D;3Ama

O2k-Application: O2

MitoPedia: SUIT - SUIT reference protocol
SUIT-category: NS(GM)
SUIT protocol pattern: lineal 1GMS;2D;3Ama

SUIT-018 O2 mt D054 is a short protocol to study th influence of the fluorescence dye on the O2 flux. During the development of this protocol the [O2] will be modified injecting nitrogen in the chamber. 

Communicated by Komlodi T  (last update 2019-03-05)
MitoPedia: SUIT

Steps and respiratory states

SUIT-018

Step State Pathway Q-junction Comment - Events (E) and Marks (M)
0DTPA
  • DTPA is an iron chelator, which decreases the chemical fluorescence background created by the Amplex UltraRed assay. Administration of DTPA into the O2k-chamber is recommended before all other chemicals because the iron chelation capacity of the compound is time-dependent (approx. 10-15 min). However, the experiments can be carried out in the absence of DTPA.
0SOD
  • SOD or superoxide dismutase converts the anion superoxide released by the mitochondria into H2O2, making it accessible to the Amplex UltraRed assay.
0HRP
  • HRP or horseradish peroxidase catalyses the conversion of Amplex UltraRed and H2O2 towards the fluorescent resorufin.
0AmR
Step State Pathway Q-junction Comment - Events (E) and Marks (M)
1GMS GMSL(n) NS CI&CII 1GMS
  • Respiratory stimulation by simultaneous action of type N substrates & succinate, with convergent electron flow in the NS-pathway for reconstitution of TCA cycle function.
  • Non-phosphorylating resting state (LEAK state); LEAK respiration L(n) in the absence of ADP, ATP, AMP (no adenylates).
2D GMSP NS CI&CII 1GMS;2D
  • Respiratory stimulation by simultaneous action of type N substrates & succinate, with convergent electron flow in the NS-pathway for reconstitution of TCA cycle function.
  • OXPHOS capacity P (with saturating [ADP]), active OXPHOS state.
3Ama ROX 1GMS;2D;3Ama
  • Rox is the residual oxygen consumption in the ROX state, due to oxidative side reactions, estimated after addition of antimycin A (inhibitor of CIII). Rox is subtracted from oxygen flux as a baseline for all respiratory states, to obtain mitochondrial respiration (mt).

Strengths and limitations

+ Reasonable duration of the experiment.
- CIV activity and cytochrome c test can be performed.

Compare SUIT protocols

References

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Qiao 2024 J Sport Health Sci2024Qiao YS, Blackwell TL, Cawthon PM, Coen PM, Cummings SR, Distefano G, Farsijani S, Forman DE, Goodpaster BH, Kritchevsky SB, Mau T, Toledo FGS, Newman AB, Glynn NW (2024) Associations of accelerometry-measured and self-reported physical activity and sedentary behavior with skeletal muscle energetics: The Study of Muscle, Mobility and Aging (SOMMA). https://doi.org/10.1016/j.jshs.2024.02.001HumanSkeletal muscle
Meszaros 2024 Transpl Int2024Meszaros AT, Weissenbacher A, Schartner M, Egelseer-Bruendl T, Hermann M, Unterweger J, Mittelberger C, Reyer BA, Hofmann J, Zelger BG, Hautz T, Resch T, Margreiter C, Maglione M, Komlódi T, Ulmer H, Cardini B, Troppmair J, Öfner D, Gnaiger E, Schneeberger S, Oberhuber R (2024) The predictive value of graft viability and bioenergetics testing towards the outcome in liver transplantation. Transpl Int 37. https://doi.org/10.3389/ti.2024.12380HumanLiver
Hardorp 2024 Bachelor-Thesis2024Hardorp RA (2024) Oxygen consumption and production measured by high-resolution respirometry in leaf preparations from Robinia pseudoacacia. Bachelor-Thesis 47 pp.Plants
Jiang 2024 Nat Metab2024Jiang S, Yuan T, Rosenberger FA, Mourier A, Dragano NRV, Kremer LS, Rubalcava-Gracia D, Hansen FM, Borg M, Mennuni M, Filograna R, Alsina D, Misic J, Koolmeister C, Papadea P, de Angelis MH, Ren L, Andersson O, Unger A, Bergbrede T, Di Lucrezia R, Wibom R, Zierath JR, Krook A, Giavalisco P, Mann M, Larsson NG (2024) Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity. Nat Metab [Epub ahead of print]. https://doi.org/10.1038/s42255-024-01038-3MouseLiver
Gross 2024 BEC2024Gross A (2024) A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part? Bioenerg Commun 2024.1. https://doi.org/10.26124/bec:2024-0001
Mahapatra 2024 J Gerontol A Biol Sci Med Sci2024Mahapatra G, Gao Z, Bateman JR 3rd, Lockhart SN, Bergstrom J, Piloso JE, Craft S, Molina AJA (2024) Peripheral blood cells from older adults exhibit sex-associated differences in mitochondrial function. J Gerontol A Biol Sci Med Sci [Epub ahead of print]. https://doi.org/10.1093/gerona/glae098HumanBlood cells
SBC 2023 Goa IN2023-12-18Goa, IN, 2023 Dec 18-20. 92nd Annual Meet of The Society of Biological Chemists (India)
AMI 2023 Jhansi IN2023-12-01Jhansi, IN, 2023 Dec 01-03. 64th Annual International Conference of the Associate of Microbiologists of India (AMI) - Microbes for LiFE (Lifestyle for environment): A strategy for well being
MAC2023 Coimbra PT2023-11-30Coimbra, PT, 2023 Nov 30 - Dec 02. MAC2023: Mitochondria in Aging, Cancer and Cell Death
5th edition Metabolism & Cancer 2023 Nice FR2023-11-22Nice, FR, 2023 Nov 22-24. 5th edition Metabolism & Cancer.
TriMAD Conference 2023 Pennsylvania US2023-11-06Pennsylvania US, 2023 Nov 06-07. 10th Translational Research in Mitochondria/Metabolism, Aging, and Disease (TRiMAD) Conference
Life Sciences Partnering 2023 Innsbruck AT2023-10-19Innsbruck, AT, Oct 19, 2023. Life Sciences Partnering 2023
MiPNet28.08 Oroboros O2k Series J manual2023-10-19
O2k-Manual
Oroboros O2k Series J manual
MiPNet28.07 NextGen-O2k Series XB manual2023-10-19
O2k-Manual
NextGen-O2k Series XB manual
MiPNet14.06 Instrumental O2 background2023-10-19
O2k-Manual
O2k Quality Control 2: Instrumental oxygen background correction and accuracy of oxygen flux.
EU-METAHEART Kick-off meeting Brussels BE2023-10-18
COST Action
EU-METAHEART
Brussels BE, 2023 October 18. EU-METAHEART Kick-off meeting - first MC meeting for COST Action project.
2nd Workshop on Mitochondrial Functional Diagnostics Innsbruck AT2023-10-16Innsbruck AT, 2023 Oct 16. 2nd Workshop on Mitochondrial Functional Diagnostics
ObesityWeek 2023 Dallas US2023-10-14Dallas, US, 2023 Oct 14-17. ObesityWeek®
MiPNet28.02 IOC162 Schroecken AT2023-10-02
O2k-Workshops.png
Schroecken AT, 2023 Oct 02-07. Oroboros O2k-Workshop on high-resolution respirometry (HRR), IOC162.
MiPNet28.10 SmartPOS-service2023-09-29
O2k-Manual
SmartPOS: Service
GFB 2023 Bedoin FR2023-09-28Bedoin, FR, Sep 28- Oct 01, 2023. 22nd GFB conference
MiPNet19.14 SOP Hamilton microsyringes2023-09-28
O2k-Manual
SOP for manual O2k-titrations with Hamilton microsyringes.
MiPNet28.09 O2k-Fluo Smart-Module manual2023-09-25
O2k-Manual
O2k-Fluo Smart-Module manual
The 6th World Cell Therapy and Regenerative Medicine Conference & Exhibition2023-09-22Taizhou, CN, 2023 Sep 22-24. The 6th World Cell Therapy and Regenerative Medicine Conference & Exhibition.
The 6th China International Biotechnology Conference & Exhibition 2023 Taizhou CN2023-09-22Taizhou, CN, 2023 Sep 22-24. The 6th China International Biotechnology Conference & Exhibition.
Physiology in Focus 2023 Tallinn EE2023-09-14Tallinn, EE, 2023 Sep 14-16. Physiology in Focus
EMC2023 Florence IT2023-09-02Florence IT, 2023 Sep 02-06. EMC 2023 50th European Muscle Conference
EBSA 2023 Stockholm SE2023-07-31Stockholm, US, 2023 Jul 31- Aug 04. 14th congress of EBSA (European Biophysical Societies’ Association)
MiP2023 Obergurgl AT2023-07-27
MiPconference
Obergurgl AT. 2023 Jul 27-30. 15th MiPconference: Bioenergetics Communications on mitObesity and Healthy Aging. - cover-to-cover following the MiPschool Obergurgl 2023
MiPschool Obergurgl 20232023-07-23
MiPschool
Obergurgl, AT. 2023-Jul-23-27. 13th MiPschool 2023: Mitochondrial structure and function, respiratory supercomplexes, and respiratory control. - satellite to MiPconference 2023
FAT4BRAIN Final review meeting Virtual2023-07-18
FAT4BRAIN
Virtual, 2023 July 18. FAT4BRAIN Final review meeting - WIDESPREAD PROJECT.
2nd Mitochondria Conference 2023 Lisbon PT2023-07-15Lisbon, PT, 2023 Jul 15-18. 2nd Mitochondria Conference from Basic Biology to Mechanisms of Disease #Mito23
37th Annual Meeting of the ISHR-ES 2023 Porto PT2023-07-10Porto, PT, 2023 Jul 10-13. 37th Annual Meeting of the International Society for Heart Research – European Section (ISHR-ES).
1st Workshop on Mitochondrial Functional Diagnostics Innsbruck AT2023-07-10Innsbruck AT, 2023 Jul 10. 1st Workshop on Mitochondrial Functional Diagnostics
ECSS 2023 Paris FR2023-07-04
ECSS
Paris, FR, 2023 Jul 4-7. 28th Annual Congress of the European college of Sport Science.
Society of Experimental Biology’s Annual Conference 2023 Edinburgh UK2023-07-04Edinburgh, UK, 2023 Jul 04-07. Society of Experimental Biology’s Annual Conference.
SHVM 2023 Graz AT2023-06-25
SHVM
Graz AT , 2022 Jun 25-28. 20th Annual Meeting of the Society for Heart and Vascular Metabolism (SHVM)
SMRM2023 Hyderabad IN2023-06-21
Society for Mitochondria Research and Medicine - India
Hyderabad IN, 2023 June 21-23. 9th Annual Conference of the SMRM on Mitochondria in Biology and Medicine.
MiPNet28.01 IOC160 Schroecken AT2023-06-19
O2k-Workshops.png
Schroecken AT, 2023 Jun 19-24. Oroboros O2k-Workshop on high-resolution respirometry (HRR), IOC160.
EUROMIT2023 Bologna IT2023-06-11Bologna, IT, Jun 11-15, 2023. EUROMIT2023 International Conference on Mitochondrial Pathology
GIBB 2023 Riva del Garda IT2023-06-08Riva del Garda, IT, 2023 Jun 08-10. International Meeting of the Italian Group of Biomembranes and Bioenergetics (GIBB)
ESCI 2023 Prague CZ2023-06-07
ESCI.JPG
Prague, CZ, 2023 Jun 7-9. 57th Annual Scientific Meeting of the European Society for Clinical Investigation, ESCI 2023.
Health Innovation Summit 2023 Vienna AT2023-06-06Vienna, AT, 2023 Jun 6. Health Innovation Summit Vienna
WISE 2023 Szeged HU2023-06-01WISE 2023 Szeged, HU, 2023 Jun 01-02. Scientific meeting to celebrate the 25th anniversary of Mihály Boros as head of the Institute of Surgical Research
DTMC2023 Wageningen NL2023-06-01Wageningen, NL, 2023 Jun 01-02. DTMC2023 - 3rd edition of the Dutch Translational Metabolism Conference.
Pint of Science 2023 Innsbruck AT2023-05-23Innsbruck, AT, 2023 May 23. A Pint of Science
BMES-SIG & MIG Conclave 2023 Virtual2023-05-23Virtual, 2023 May 23-24. BMES-SIG & MIG Conclave
FEBS 2023 Luso PT2023-05-22
FEBS
Luso, PT. 2023 May 22-25. 1st 1st FEBS Workshop “Redox Medicine Workshop: From Cellular Signaling to systems physiology and therapeutic targe”s”.
DORA and Bioenergetics Communications2023-05-16Innsbruck, AT, 2023 May 16. DORA and Bioenergetics Communications
2nd Oroboros distributor training 2023 Innsbruck AT2023-04-24
NextGenO2k logo.jpg
Innsbruck AT, 2023 Nov 07-09 2nd Oroboros distributor training.
Oroboros distributor training 2023 Innsbruck AT2023-04-24
NextGenO2k logo.jpg
Innsbruck AT, 2023 Apr 24-25 Oroboros distributor training.
Mitochondrial Dysfunction and Neurodegeneration 2023 Nottingham UK2023-04-20
Biochemical Society
Nottingham, UK, 2023 Apr 20-21. Mitochondrial Dysfunction and Neurodegeneration Conference
FAT4BRAIN 2023 Riga LV2023-04-20
FAT4BRAIN
Riga LV, 2023 April 20-21. FAT4BRAIN Symposium - Novel drug target and pathway identification
MiPNet28.04 FAT4BRAIN IOC159 Riga LV2023-04-19
FAT4BRAIN
Riga, LV, 2023 Apr 19. FAT4BRAIN O2k-Workshop IOC159.
ATSPB 2023 Hall AT2023-04-13Hall in Tirol, AT, 2023 Apr 13-15. ATSPB 2023: Plants in the context of food security, biodiversity and climate change
MiPNet28.06 IOC161 Coimbra PT2023-04-12
O2k-Network
Cantanhede, PT, 2023 Apr 12. Oroboros O2k-Workshop on high-resolution respirometry (HRR), IOC161.
12th International Conference on Obesity and Eating Disorders 2023 Vienna AT2023-04-10Vienna, AT, 2023 Apr 10-11. 12th International Conference on Obesity and Eating Disorders.
PDBEB 2023 Coimbra PT2023-04-03Coimbra, PT, 2023 Apr 03-14. PHD Course in Experimental Biology and Biomedicine - ONE HEALTH: A Metabolic Approach from the Cell to Society
Padua Days 2023 Padua IT2023-03-29Padua, IT, 2023 Mar 29 - Apr 01. Padua Days on Muscle & Mobility Medicine
CFAS Symposium 2023 Copenhagen DK2023-03-23Copenhagen, DK, 2023 Mar 23. CFAS 2023 Symposium on “Exercise as Medicine”.
6th Research Day Innsbruck AT2023-03-20Innsbruck, AT, 2023 Mar 20. 6th Research Day
MiPNet19.03 O2k-cleaning and ISS2023-03-14
O2k-Manual
O2k-Chamber cleaning SOP and Integrated Suction System (ISS).
MiPNet22.11 O2k-FluoRespirometer manual2023-03-14
O2k-Manual
O2k-FluoRespirometer manual.
MiPNet28.05 IOC158 Innsbruck AT2023-02-27
OROBOROS-solo.png
Innsbruck AT, 2023 Feb 27 - Mar 01. O2k-Coaching Days - Basic, IOC158.
BPS2023 San Diego US2023-02-18San Diego, US, 2023 Feb 18-22. 67th Annual Meeting of the Biophysical Society.
International Symposium on Mitochondria, Cell Death and Human Diseases 2023 New Delhi IN2023-02-18New Delhi, IN, 2023 Feb 18-19. International Symposium on “Mitochondria, Cell Death and Human Diseases”
MiPNet28.03 IOC157 Los Angeles US2023-02-14
O2k-Network
Los Angeles, CA US, 2023 Feb 14-16. Oroboros O2k-Workshop on high-resolution respirometry (HRR), IOC157.
FAT4BRAIN ESR Workshop2023-02-09
FAT4BRAIN
Riga, LV, 2023 February 09-10. FAT4BRAIN ESR Workshop - WIDESPREAD PROJECT.
International Hypoxia Symposium 2023 Chateau Lake Louise CA2023-02-07Chateau Lake Louise, Alberta, CA, 2023 Feb 07-12. International Hypoxia Symposium 2023
MiPNet06.03 POS-calibration-SOP2023-02-06
O2k-Manual
O2k Quality Control 1: Polarographic oxygen sensors and accuracy of calibration.
EPN Autumn School Series Ebsdorfergrund DE2023-02-05Ebsdorfergrund, DE, 2023 Sep 02-10. The European Psychoneuroimmunology Autumn School Series - the skin-brain axis and the breaking of barriers.
GRC Mitochondria in Health and Disease 2023 Lucca IT2023-02-05
Grc logo.png
Lucca (Barga), IT, 2023 Feb 05-10. The Gordon Research Conference on Mitochondria in Health and Disease.
Moellering 2023 Arthritis Res Ther2023Moellering DR, Smith-Johnston K, Kelley C, Sammy MJ, Benedict J, Brock G, Johnson J, Baskin KK, Jarjour WN, Belury MA, Reiser PJ, Nagareddy PR, Hanaoka BY (2023) Association between skeletal muscle mitochondrial dysfunction and insulin resistance in patients with rheumatoid arthritis: a case-control study. https://doi.org/10.1186/s13075-023-03065-zHumanSkeletal muscle
Zhang 2023 J Cachexia Sarcopenia Muscle2023Zhang S, Yan H, Ding J, Wang R, Feng Y, Zhang X, Kong X, Gong H, Lu X, Ma A, Hua Y, Liu H, Guo J, Gao H, Zhou Z, Wang R, Chen P, Liu T, Kong X (2023) Skeletal muscle-specific DJ-1 ablation-induced atrogenes expression and mitochondrial dysfunction contributing to muscular atrophy. https://doi.org/10.1002/jcsm.13290MouseSkeletal muscle
Liu 2023 Pharmacol Res2023Liu S, Yue S, Guo Y, Han JY, Wang H (2023) Sorafenib induces cardiotoxicity through RBM20-mediated alternative splicing of sarcomeric and mitochondrial genes. https://doi.org/10.1016/j.phrs.2023.107017RatHeart
Sadri 2023 Arch Biochem Biophys2023Sadri S, Tomar N, Yang C, Audi SH, Cowley AW Jr, Dash RK (2023) Effects of ROS pathway inhibitors and NADH and FADH2 linked substrates on mitochondrial bioenergetics and ROS emission in the heart and kidney cortex and outer medulla. Arch Biochem Biophys 744:109690. https://doi.org/10.1016/j.abb.2023.109690RatHeart
Kidney
Wu 2023 Int Immunopharmacol2023Wu F, Zhang YT, Teng F, Li HH, Guo SB (2023) S100a8/a9 contributes to sepsis-induced cardiomyopathy by activating ERK1/2-Drp1-mediated mitochondrial fission and respiratory dysfunction. https://doi.org/10.1016/j.intimp.2023.109716MouseHeart
National Academies of Sciences, Engineering, and Medicine 2023 BMI and beyond2023National Academies of Sciences, Engineering, and Medicine (2023) BMI and beyond: Considering context in measuring obesity and its applications: Proceedings of a workshop—in brief. The National Academies Press, Washington, DC. https://doi.org/10.17226/27185HumanFat
Ferraretti 2023 bioRxiv2023Ferraretti G, Abondio P, Alberti M, Dezi A, Sherpa PT, Cocco P, Tiriticco M, di Marcello M, Gnecchi-Ruscone GA, Natali L, Corcelli A, Marinelli G, Peluzzi D, Sarno S, Sazzini M (2023) Archaic introgression contributed to shape the adaptive modulation of angiogenesis and nitric oxide induction in human high-altitude populations from the Himalayas. https://doi.org/10.1101/2023.05.23.540768
Davis 2023 MitoFit2023Davis MS, Barrett MR, Bayly WM, Bolinger A (2023) Effect of selected fluorophores on equine skeletal muscle mitochondrial respiration. MitoFit Preprints 2023.5. https://doi.org/10.26124/mitofit:2023-0005 — 2024-04-25 published in Bioenerg Commun 2024.2.HorseSkeletal muscle
Liufu 2023 Front Physiol2023Liufu T, Yu H, Yu J, Yu M, Tian Y, Ou Y, Deng J, Xing G, Wang Z (2023) Complex I deficiency in m.3243A>G fibroblasts is alleviated by reducing NADH accumulation. Front Physiol 14:1164287. https://doi.org/10.3389/fphys.2023.1164287
Santos-Silva 2023 Transl Psychiatry2023Santos-Silva T, Hazar Ülgen D, Lopes CFB, Guimarães FS, Alberici LC, Sandi C, Gomes FV (2023) Transcriptomic analysis reveals mitochondrial pathways associated with distinct adolescent behavioral phenotypes and stress response. https://doi.org/10.1038/s41398-023-02648-3RatNervous system
Mahmoud 2023 Pharmacol Res2023Mahmoud AM, Kostrzewa M, Marolda V, Cerasuolo M, Maccarinelli F, Coltrini D, Rezzola S, Giacomini A, Mollica MP, Motta A, Paris D, Zorzano A, Marzo VD, Ronca R, Ligresti A (2023) Cannabidiol alters mitochondrial bioenergetics via VDAC1 and triggers cell death in hormone-refractory prostate cancer. https://doi.org/10.1016/j.phrs.2023.106683MouseEndothelial;epithelial;mesothelial cell
Arias-Reyes 2023 MitoFit2023Arias-Reyes C, Aliaga-Raduán F, Pinto-Aparicio R, Joseph V, Soliz J (2023) Mitochondrial plasticity in the retrosplenial cortex enhances ATP synthesis during acclimatization to hypoxia in mice but not in rats. MitoFit Preprints 2023.6. https://doi.org/10.26124/mitofit:2023-0006Mouse
Rat		Nervous system
Che 2023 Plant Cell Environ2023Che X, Zhang T, Li H, Li Y, Zhang L, Liu J (2023) Nighttime hypoxia effects on ATP availability for photosynthesis in seagrass. Plant Cell Environ 46:2841-50. https://doi.org/10.1111/pce.14654
MiPNet25.16 Virtual O2k-Workshop HRR2023
O2k-Workshops.png
Virtual O2k-Workshop on high-resolution respirometry (HRR) - Basic and Advanced (O2 and H2O2 fluxes)
Galli 2023 Comp Biochem Physiol A Mol Integr Physiol2023Galli GLJ, Shiels HA, White E, Couturier CS, Stecyk JAW (2023) The air-breathing Alaska blackfish (Dallia pectoralis) suppresses brain mitochondrial reactive oxygen species to survive cold hypoxic winters. https://doi.org/10.1016/j.cbpa.2022.111355FishesNervous system
Dewidar 2023 EBioMedicine2023Dewidar B, Mastrototaro L, Englisch C, Ress C, Granata C, Rohbeck E, Pesta D, Heilmann G, Wolkersdorfer M, Esposito I, Reina Do Fundo M, Zivehe F, Yavas A, Roden M (2023) Alterations of hepatic energy metabolism in murine models of obesity, diabetes and fatty liver diseases. https://doi.org/10.1016/j.ebiom.2023.104714MouseSkeletal muscle
Liver
Whytock 2023 Am J Physiol Endocrinol Metab2023Whytock KL, Pino MF, Sun Y, Yu G, De Carvalho FG, Yeo RX, Vega RB, Parmar G, Divoux A, Kapoor N, Yi F, Cornnell H, Patten DA, Harper ME, Gardell SJ, Smith SR, Walsh MJ, Sparks LM (2023) Comprehensive interrogation of human skeletal muscle reveals a dissociation between insulin resistance and mitochondrial capacity. https://doi.org/10.1152/ajpendo.00143.2023
Tian 2023 Redox Biol2023Tian G, Zhou J, Quan Y, Kong Q, Li J, Xin Y, Wu W, Tang X, Liu X (2023) Voltage-dependent anion channel 1 (VDAC1) overexpression alleviates cardiac fibroblast activation in cardiac fibrosis via regulating fatty acid metabolism. https://doi.org/10.1016/j.redox.2023.102907MouseHeart
Fibroblast
Lee 2023 Antioxidants (Basel)2023Lee WE, Genetzakis E, Figtree GA (2023) Novel strategies in the early detection and treatment of endothelial cell-specific mitochondrial dysfunction in coronary artery disease. Antioxidants (Basel) 12:1359. https://doi.org/10.3390/antiox12071359
Liu 2023 Int J Biol Sci2023Liu Y, Sun Y, Guo Y, Shi X, Chen X, Feng W, Wu LL, Zhang J, Yu S, Wang Y, Shi Y (2023) An overview: the diversified role of mitochondria in cancer metabolism. Int J Biol Sci 19:897-915. https://doi.org/10.7150/ijbs.81609
Li 2023 Nature2023Li Q, Orcutt K, Cook RL, Sabines-Chesterking J, Tong AL, Schlau-Cohen GS, Zhang X, Fleming GR, Whaley KB (2023) Single-photon absorption and emission from a natural photosynthetic complex. Nature 619:300-4. https://doi.org/10.1038/s41586-023-06121-5Eubacteria
Chavda 2023 Antioxidants (Basel)2023Chavda V, Lu B (2023) Reverse electron transport at mitochondrial Complex I in ischemic stroke, aging, and age-related diseases. Antioxidants (Basel) 12:895. https://doi.org/10.3390/antiox12040895
Walsh 2023 FASEB J2023Walsh MA, Musci RV, Jacobs RA, Hamilton KL (2023) A practical perspective on how to develop, implement, execute, and reproduce high-resolution respirometry experiments: The physiologist's guide to an Oroboros O2k. https://doi.org/10.1096/fj.202301644rr
Kutschka 2023 Basic Res Cardiol2023Kutschka I, Bertero E, Wasmus C, Xiao K, Yang L, Chen X, Oshima Y, Fischer M, Erk M, Arslan B, Alhasan L, Grosser D, Ermer KJ, Nickel A, Kohlhaas M, Eberl H, Rebs S, Streckfuss-Bömeke K, Schmitz W, Rehling P, Thum T, Higuchi T, Rabinowitz J, Maack C, Dudek J (2023) Activation of the integrated stress response rewires cardiac metabolism in Barth syndrome. https://doi.org/10.1007/s00395-023-01017-xMouseHeart
Deschemin 2023 Sci Rep2023Deschemin JC, Ransy C, Bouillaud F, Chung S, Galy B, Peyssonnaux C, Vaulont S (2023) Hepcidin deficiency in mice impairs white adipose tissue browning possibly due to a defect in de novo adipogenesis. https://doi.org/10.1038/s41598-023-39305-0MouseFat
Doke 2023 Nat Metab2023Doke T, Mukherjee S, Mukhi D, Dhillon P, Abedini A, Davis JG, Chellappa K, Chen B, Baur JA, Susztak K (2023) NAD+ precursor supplementation prevents mtRNA/RIG-I-dependent inflammation during kidney injury. https://doi.org/10.1038/s42255-023-00761-7HumanKidney
Goetzman 2023 Antioxidants (Basel)2023Goetzman E, Gong Z, Zhang B, Muzumdar R (2023) Complex II biology in aging, health, and disease. Antioxidants (Basel) 12:1477. https://doi.org/10.3390/antiox12071477
Giovarelli 2023 Mol Med2023Giovarelli M, Serati A, Zecchini S, Guelfi F, Clementi E, Mandò C (2023) Cryopreserved placental biopsies maintain mitochondrial activity for high-resolution respirometry. https://doi.org/10.1186/s10020-023-00645-2HumanGenital
Curtabbi 2023 Redox Biol2023Curtabbi A, Guarás A, Cabrera-Alarcón JL, Rivero M, Calvo E, Rosa-Moreno M, Vázquez J, Medina M, Enríquez JA (2023) Regulation of respiratory complex I assembly by FMN cofactor targeting. https://doi.org/10.1016/j.redox.2023.103001MouseFibroblast
Kidney
Flockhart 2023 Redox Biol2023Flockhart M, Nilsson LC, Tillqvist EN, Vinge F, Millbert F, Lännerström J, Nilsson PH, Samyn D, Apró W, Sundqvist ML, Larsen FJ (2023) Glucosinolate-rich broccoli sprouts protect against oxidative stress and improve adaptations to intense exercise training. https://doi.org/10.1016/j.redox.2023.102873
Begum 2023 WIREs Mech Dis2023Begum HM, Shen K (2023) Intracellular and microenvironmental regulation of mitochondrial membrane potential in cancer cells. WIREs Mech Dis 15:e1595. https://doi.org/10.1002/wsbm.1595
Clemente 2023 Commun Biol2023Clemente N, Baroni S, Fiorilla S, Tasso F, Reano S, Borsotti C, Ruggiero MR, Alchera E, Corrazzari M, Walker G, Follenzi A, Crich SG, Carini R (2023) Boosting intracellular sodium selectively kills hepatocarcinoma cells and induces hepatocellular carcinoma tumor shrinkage in mice. https://doi.org/10.1038/s42003-023-04946-4HumanLiver
MiP2023 Bioenerg Commun2023Gnaiger E, Timon-Gomez A, Tindle-Solomon L, Cocco P, eds (2023) MiPschool and MiPconference 2023 . Bioenerg Commun 2023.2. https://doi.org/10.26124/bec:2023-0002
Yang 2023 Cell Death Discov2023Yang H, Gao Y, Xu D, Xu K, Liang SQ, Yang Z, Scherz A, Hall SRR, Forster S, Berezowska S, Yao F, Ochsenbein AF, Marti TM, Kocher GJ, Schmid RA, Dorn P, Peng RW (2023) MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma. https://doi.org/10.1038/s41420-023-01307-2HumanLung;gill
Endothelial;epithelial;mesothelial cell
Glombik 2023 Int J Mol Sci2023Glombik K, Kukla-Bartoszek M, Curzytek K, Detka J, Basta-Kaim A, Budziszewska B (2023) The effects of prenatal dexamethasone exposure on brain metabolic homeostasis in adulthood: implications for depression. Int J Mol Sci 24:1156. https://doi.org/10.3390/ijms24021156RatNervous system
Ashok 2023 Mol Cell Biochem2023Ashok S, Raji SR, Manjunatha S, Srinivas G (2023) Impairment of substrate-mediated mitochondrial respiration in cardiac cells by chloroquine. https://doi.org/10.1007/s11010-023-04740-0MouseHeart
Kugler 2023 J Appl Physiol (1985)2023Kugler BA, Thyfault JP, McCoin CS (2023) Sexually dimorphic hepatic mitochondrial adaptations to exercise: a mini-review. J Appl Physiol (1985) 134:685-91. https://doi.org/10.1152/japplphysiol.00711.2022Liver
Kamienieva 2023 Biochim Biophys Acta Mol Basis Dis2023Kamienieva I, Charzyńska A, Duszyński J, Malińska D, Szczepanowska J (2023) In search for mitochondrial biomarkers of Parkinson's disease: Findings in parkin-mutant human fibroblasts. https://doi.org/10.1016/j.bbadis.2023.166787HumanFibroblast
Horcas-Nieto 2023 Biochim Biophys Acta Mol Basis Dis2023Horcas-Nieto JM, Versloot CJ, Langelaar-Makkinje M, Gerding A, Blokzijl T, Koster MH, Baanstra M, Martini IA, Coppes RP, Bourdon C, van Ijzendoorn SCD, Kim P, Bandsma RHJ, Bakker BM (2023) Organoids as a model to study intestinal and liver dysfunction in severe malnutrition. https://doi.org/10.1016/j.bbadis.2022.166635MouseLiver
Other cell lines
Bellissimo 2023 Exp Physiol2023Bellissimo CA, Castellani LN, Finch MS, Murugathasan M, Gandhi S, Sweeney G, Abdul-Sater AA, MacPherson REK, Perry CGR (2023) Memory impairment in the D2.mdx mouse model of Duchenne muscular dystrophy is prevented by the adiponectin receptor agonist ALY688. https://doi.org/10.1113/ep091274MouseNervous system
MiPNet26.07 Installation and startup support session2023
O2k-Workshops.png
Virtual Oroboros Installation and startup support session
Pacheco-Fuentes 2023 Oecologia2023Pacheco-Fuentes H, Ton R, Griffith SC (2023) Short- and long-term consequences of heat exposure on mitochondrial metabolism in zebra finches (Taeniopygia castanotis). https://doi.org/10.1007/s00442-023-05344-7BirdsBlood cells
Park 2023 Nature2023Park M, Leahey E, Funk RJ (2023) Papers and patents are becoming less disruptive over time. Nature 613:138-44. https://doi.org/10.1038/s41586-022-05543-x
Antona 2023 Cell Death Discov2023Antona A, Leo G, Favero F, Varalda M, Venetucci J, Faletti S, Todaro M, Mazzucco E, Soligo E, Saglietti C, Stassi G, Manfredi M, Pelicci G, Corà D, Valente G, Capello D (2023) Targeting lysine-specific demethylase 1 (KDM1A/LSD1) impairs colorectal cancer tumorigenesis by affecting cancer cells stemness, motility, and differentiation. https://doi.org/10.1038/s41420-023-01502-1HumanEndothelial;epithelial;mesothelial cell
Kumar 2023 J Nutr Biochem2023Kumar A, Bellar A, Mishra S, Sekar J, Welch N, Dasarathy S (2023) L-Isoleucine reverses hyperammonemia-induced myotube mitochondrial dysfunction and post-mitotic senescence. https://doi.org/10.1016/j.jnutbio.2023.109498
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Pharaoh 2023 Geroscience2023Pharaoh G, Kamat V, Kannan S, Stuppard RS, Whitson J, Martín-Pérez M, Qian WJ, MacCoss MJ, Villén J, Rabinovitch P, Campbell MD, Sweet IR, Marcinek DJ (2023) The mitochondrially targeted peptide elamipretide (SS-31) improves ADP sensitivity in aged mitochondria by increasing uptake through the adenine nucleotide translocator (ANT). https://doi.org/10.1007/s11357-023-00861-yMouseSkeletal muscle
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Koizumi 2023 Front Cardiovasc Med2023Koizumi T, Watanabe M, Yokota T, Tsuda M, Handa H, Koya J, Nishino K, Tatsuta D, Natsui H, Kadosaka T, Koya T, Nakao M, Hagiwara H, Kamada R, Temma T, Tanaka S, Anzai T (2023) Empagliflozin suppresses mitochondrial reactive oxygen species generation and mitigates the inducibility of atrial fibrillation in diabetic rats. Front Cardiovasc Med 10: 1005408.RatHeart
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Silaidos 2023 Geroscience2023Silaidos CV, Reutzel M, Wachter L, Dieter F, Ludin N, Blum WF, Wudy SA, Matura S, Pilatus U, Hattingen E, Pantel J, Eckert GP (2023) Age-related changes in energy metabolism in peripheral mononuclear blood cells (PBMCs) and the brains of cognitively healthy seniors. https://doi.org/10.1007/s11357-023-00810-9HumanBlood cells
Nijholt 2023 Sci Rep2023Nijholt KT, Sánchez-Aguilera PI, Mahmoud B, Gerding A, Wolters JC, Wolters AHG, Giepmans BNG, Silljé HHW, de Boer RA, Bakker BM, Westenbrink BD (2023) A Kinase Interacting Protein 1 regulates mitochondrial protein levels in energy metabolism and promotes mitochondrial turnover after exercise. https://doi.org/10.1038/s41598-023-45961-zMouseHeart
Sucha 2023 Int J Mol Sci2023Sucha M, Benediktova S, Tichanek F, Jedlicka J, Kapl S, Jelinkova D, Purkartova Z, Tuma J, Kuncova J, Cendelin J (2023) Experimental treatment with edaravone in a mouse model of spinocerebellar ataxia 1. https://doi.org/10.3390/ijms241310689MouseNervous system
Mueller 2023 Int J Mol Sci2023Müller M, Donhauser E, Maske T, Bischof C, Dumitrescu D, Rudolph V, Klinke A (2023) Mitochondrial integrity is critical in right heart failure development. Int J Mol Sci 24:11108. https://doi.org/10.3390/ijms241311108Heart
Noone 2023 Cell Signal2023Noone J, Rochfort KD, O'Sullivan F, O'Gorman DJ (2023) SIRT4 is a regulator of human skeletal muscle fatty acid metabolism influencing inner and outer mitochondrial membrane-mediated fusion. https://doi.org/10.1016/j.cellsig.2023.110931HumanSkeletal muscle
Li 2023 Cell Rep2023Li BY, Peng WQ, Liu Y, Guo L, Tang QQ (2023) HIGD1A links SIRT1 activity to adipose browning by inhibiting the ROS/DNA damage pathway. https://doi.org/10.1016/j.celrep.2023.112731
Bahire 2023 Mitochondrion2023Bahire KL, Maļuhins R, Bello F, Freitag SV, Jeļisejevs I, Gile R, Upīte J, Plesnila N, Jansone B (2023) Hemispheric analysis of mitochondrial complex I and II activity in the mouse model of ischemia-reperfusion-induced injury. https://doi.org/10.1016/j.mito.2023.02.005MouseNervous system
Cortes 2023 Nat Commun2023Cortés M, Brischetto A, Martinez-Campanario MC, Ninfali C, Domínguez V, Fernández S, Celis R, Esteve-Codina A, Lozano JJ, Sidorova J, Garrabou G, Siegert AM, Enrich C, Pintado B, Morales-Ruiz M, Castro P, Cañete JD, Postigo A (2023) Inflammatory macrophages reprogram to immunosuppression by reducing mitochondrial translation. https://doi.org/10.1038/s41467-023-42277-4HumanBlood cells
Awad-Igbaria 2023 J Transl Med2023Awad-Igbaria Y, Ferreira N, Keadan A, Sakas R, Edelman D, Shamir A, Francous-Soustiel J, Palzur E (2023) HBO treatment enhances motor function and modulates pain development after sciatic nerve injury via protection the mitochondrial function. https://doi.org/10.1186/s12967-023-04414-xRatNervous system
Gaudo 2023 Free Radic Biol Med2023Gaudó P, de Tomás-Mateo E, Garrido-Pérez N, Santana A, Ruiz-Pesini E, Montoya J, Bayona-Bafaluy P (2023) "ATAD3C regulates ATAD3A assembly and function in the mitochondrial membrane". https://doi.org/10.1016/j.freeradbiomed.2023.12.006HumanFibroblast
Morales-Rubio 2023 Sci Rep2023Morales-Rubio R, Bernal-Ramírez J, Rubio-Infante N, Luévano-Martínez LA, Ríos A, Escalante BA, García-Rivas G, Rodríguez González J (2023) Cellular shortening and calcium dynamics are improved by noisy stimulus in a model of cardiomyopathy. https://doi.org/10.1038/s41598-023-41611-6MouseHeart
Smith 2023 Nat Rev Mol Cell Biol2023Smith JAB, Murach KA, Dyar KA, Zierath JR (2023) Exercise metabolism and adaptation in skeletal muscle. Nat Rev Mol Cell Biol 24:607-32. https://doi.org/10.1038/s41580-023-00606-x
Menail 2023 FASEB J2023Menail HA, Cormier SB, Léger A, Robichaud S, Hebert-Chatelain E, Lamarre SG, Pichaud N (2023) Age-related flexibility of energetic metabolism in the honey bee Apis mellifera. https://doi.org/10.1096/fj.202300654rHexapods
Schniertshauer 2023 Curr Issues Mol Biol2023Schniertshauer D, Wespel S, Bergemann J (2023) Natural mitochondria targeting substances and their effect on cellular antioxidant system as a potential benefit in mitochondrial medicine for prevention and remediation of mitochondrial dysfunctions. Curr Issues Mol Biol 45:3911-32. https://doi.org/10.3390/cimb45050250
Czyzowska 2023 Redox Biol2023Czyżowska A, Brown J, Xu H, Sataranatarajan K, Kinter M, Tyrell VJ, O'Donnell VB, Van Remmen H (2023) Elevated phospholipid hydroperoxide glutathione peroxidase (GPX4) expression modulates oxylipin formation and inhibits age-related skeletal muscle atrophy and weakness. https://doi.org/10.1016/j.redox.2023.102761MouseSkeletal muscle
Ren 2023 Cell Discov2023Ren X, Yan J, Zhao Q, Bao X, Han X, Zheng C, Zhou Y, Chen L, Wang B, Yang L, Lin X, Liu D, Lin Y, Li M, Fang H, Lu Z, Lyu J (2023) The Fe-S cluster assembly protein IscU2 increases α-ketoglutarate catabolism and DNA 5mC to promote tumor growth. https://doi.org/10.1038/s41421-023-00558-8HumanIslet cell;pancreas;thymus
Vamesu 2023 JCI Insight2023Vamesu BM, Nicola T, Li R, Hazra S, Matalon S, Kaminski N, Ambalavanan N, Kandasamy J (2023) Thyroid hormone modulates hyperoxic neonatal lung injury and mitochondrial function. https://doi.org/10.1172/jci.insight.160697MouseLung;gill
Fisar 2023 Biomedicines2023Fišar Z, Hroudová J, Zvěřová M, Jirák R, Raboch J, Kitzlerová E (2023) Age-dependent alterations in platelet mitochondrial respiration. https://doi.org/10.3390/biomedicines11061564HumanPlatelet
Kobayashi 2023 Int J Mol Sci2023Kobayashi A, Takeiwa T, Ikeda K, Inoue S (2023) Roles of noncoding RNAs in regulation of mitochondrial electron transport chain and oxidative phosphorylation. Int J Mol Sci 24:9414. https://doi.org/10.3390/ijms24119414
Wider 2023 Crit Care2023Wider JM, Gruley E, Morse PT, Wan J, Lee I, Anzell AR, Fogo GM, Mathieu J, Hish G, O’Neil B, Neumar RW, Przyklenk K, Hüttemann M, Sanderson TH (2023) Modulation of mitochondrial function with near-infrared light reduces brain injury in a translational model of cardiac arrest. Crit Care 27:491. https://doi.org/10.1186/s13054-023-04745-7
Chang 2023 Front Endocrinol (Lausanne)2023Chang JS (2023) Recent insights into the molecular mechanisms of simultaneous fatty acid oxidation and synthesis in brown adipocytes. Front Endocrinol (Lausanne) 14:1106544. https://doi.org/10.3389/fendo.2023.1106544
Salmon 2023 Geroscience2023Salmón P, Millet C, Selman C, Monaghan P, Dawson NJ (2023) Tissue-specific reductions in mitochondrial efficiency and increased ROS release rates during ageing in zebra finches, Taeniopygia guttata. https://doi.org/10.1007/s11357-022-00624-1BirdsSkeletal muscle
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Dominguez-Lopez 2023 Neuropharmacology2023Dominguez-Lopez S, Ahn B, Sataranatarajan K, Ranjit R, Premkumar P, Van Remmen H, Beckstead MJ (2023) Long-term methamphetamine self-administration increases mesolimbic mitochondrial oxygen consumption and decreases striatal glutathione. https://doi.org/10.1016/j.neuropharm.2023.109436MouseNervous system
Mousa 2023 Cell Rep2023Mousa MG, Vuppaladhadiam L, Kelly MO, Pietka T, Ek S, Shen KC, Meyer GA, Finck BN, Brookheart RT (2023) Site-1 protease inhibits mitochondrial respiration by controlling the TGF-β target gene Mss51. Cell Rep 42:112336. https://doi.org/10.1016/j.celrep.2023.112336MouseSkeletal muscle
Du Z 2023 Proc Natl Acad Sci U S A2023Du Z, Zhou X, Lai Y, Xu J, Zhang Y, Zhou S, Feng Z, Yu L, Tang Y, Wang W, Yu L, Tian C, Ran T, Chen H, Guddat LW, Liu F, Gao Y, Rao Z, Gong H (2023) Structure of the human respiratory complex II. Proc Natl Acad Sci U S A 120:e2216713120. https://doi.org/10.1073/pnas.2216713120Human
Kankuri 2023 Exp Mol Med2023Kankuri E, Finckenberg P, Leinonen J, Tarkia M, Björk S, Purhonen J, Kallijärvi J, Kankainen M, Soliymani R, Lalowski M, Mervaala E (2023) Altered acylcarnitine metabolism and inflexible mitochondrial fuel utilization characterize the loss of neonatal myocardial regeneration capacity. https://doi.org/10.1038/s12276-023-00967-5MouseHeart
Fleischman 2023 Mol Metab2023Fleischman JY, Van den Bergh F, Collins NL, Bowers M, Beard DA, Burant CF (2023) Higher mitochondrial oxidative capacity is the primary molecular differentiator in muscle of rats with high and low intrinsic cardiorespiratory fitness. https://doi.org/10.1016/j.molmet.2023.101793RatHeart
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Cojocaru 2023 Antioxidants (Basel)2023Cojocaru KA, Luchian I, Goriuc A, Antoci LM, Ciobanu CG, Popescu R, Vlad CE, Blaj M, Foia LG (2023) Mitochondrial dysfunction, oxidative stress, and therapeutic strategies in diabetes, obesity, and cardiovascular disease. Antioxidants (Basel) 12:658. https://doi.org/10.3390/antiox12030658
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Pendleton 2023 Front Cell Dev Biol2023Pendleton KE, Wang K, Echeverria GV (2023) Rewiring of mitochondrial metabolism in therapy-resistant cancers: permanent and plastic adaptations. Front Cell Dev Biol 11:1254313. https://doi.org/10.3389/fcell.2023.1254313
Szulik 2023 Basic Res Cardiol2023Szulik MW, Valdez S, Walsh M, Davis K, Bia R, Horiuchi E, O'Very S, Laxman AK, Sandaklie-Nicolova L, Eberhardt DR, Durrant JR, Sheikh H, Hickenlooper S, Creed M, Brady C, Miller M, Wang L, Garcia-Llana J, Tracy C, Drakos SG, Funai K, Chaudhuri D, Boudina S, Franklin S (2023) SMYD1a protects the heart from ischemic injury by regulating OPA1-mediated cristae remodeling and supercomplex formation. https://doi.org/10.1007/s00395-023-00991-6MouseHeart
Pereyra 2023 Am J Physiol Gastrointest Liver Physiol2023Pereyra AS, McLaughlin KL, Buddo KA, Ellis JM (2023) Medium-chain fatty acid oxidation is independent of L-carnitine in liver and kidney but not in heart and skeletal muscle. https://doi.org/10.1152/ajpgi.00105.2023MouseHeart
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Verkhratsky 2023 Function (Oxf)2023Verkhratsky A, Petersen OH (2023) How do we clean up the scientific record? Function (Oxf) 4:zqad055. https://doi.org/10.1093/function/zqad055
Bellissimo 2023 BEC2023Bellissimo CA, Soendergaard S, Hughes MC, Ramos SV, Larsen S, Perry CGR (2023) The influence of adenylate cycling on mitochondrial calcium-induced permeability transition in permeabilized skeletal muscle fibers. Bioenerg Commun 2023.1. https://doi.org/10.26124/bec:2023-0001MouseSkeletal muscle
Wikstroem 2023 Biochim Biophys Acta Bioenerg2023Wikström M, Gennis RB, Rich PR (2023) Structures of the intermediates in the catalytic cycle of mitochondrial cytochrome c oxidase. Biochim Biophys Acta Bioenerg 1864:148933. https://doi.org/10.1016/j.bbabio.2022.148933
Preston 2023 Academic Press2023Preston G, El Soufi El Sabbagh D, Emmerzaal TL, Morava E, Andreazza AC, Rahman S, Kozicz T (2023) Antidepressants, mood-stabilizing drugs, and mitochondrial functions: For better or for worse. In: de Oliveira MR (ed) Mitochondrial intoxication:323-49. Academic Press. https://doi.org/10.1016/B978-0-323-88462-4.00016-X
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Fernando 2023 Commun Biol2023Fernando R, Shindyapina AV, Ost M, Santesmasses D, Hu Y, Tyshkovskiy A, Yim SH, Weiss J, Gladyshev VN, Grune T, Castro JP (2023) Downregulation of mitochondrial metabolism is a driver for fast skeletal muscle loss during mouse aging. https://doi.org/10.1038/s42003-023-05595-3MouseSkeletal muscle
Martell 2023 Nat Commun2023Martell E, Kuzmychova H, Kaul E, Senthil H, Chowdhury SR, Morrison LC, Fresnoza A, Zagozewski J, Venugopal C, Anderson CM, Singh SK, Banerji V, Werbowetski-Ogilvie TE, Sharif T (2023) Metabolism-based targeting of MYC via MPC-SOD2 axis-mediated oxidation promotes cellular differentiation in group 3 medulloblastoma. https://doi.org/10.1038/s41467-023-38049-9HumanNervous system
Diaz 2023 Front Mol Biosci2023Diaz EC, Adams SH, Weber JL, Cotter M, Børsheim E (2023) Elevated LDL-C, high blood pressure, and low peak V˙O2 associate with platelet mitochondria function in children-The Arkansas Active Kids Study. Front Mol Biosci 10:1136975. https://doi.org/10.3389/fmolb.2023.1136975HumanBlood cells
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Mould 2023 Front Physiol2023Mould RR, Kalampouka I, Thomas EL, Guy GW, Nunn AVW, Bell JD (2023) Non-chemical signalling between mitochondria. Front Physiol 14:1268075. https://doi.org/10.3389/fphys.2023.1268075
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Palma 2023 Oncogene2023Palma FR, Gantner BN, Sakiyama MJ, Kayzuka C, Shukla S, Lacchini R, Cunniff B, Bonini MG (2023) ROS production by mitochondria: function or dysfunction?. Oncogene https://doi.org/10.1038/s41388-023-02907-z
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Temelie 2023 Int J Mol Sci2023Temelie M, Talpur R, Dominguez-Prieto M, Dantas Silva A, Cenusa C, Craciun L, Savu DI, Moisoi N (2023) Impaired integrated stress response and mitochondrial integrity modulate genotoxic stress impact and lower the threshold for immune signalling. https://doi.org/10.3390/ijms24065891MouseFibroblast
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Hryc 2023 Nat Commun2023Hryc CF, Mallampalli VKPS, Bovshik EI, Azinas S, Fan G, Serysheva II, Sparagna GC, Baker ML, Mileykovskaya E, Dowhan W (2023) Structural insights into cardiolipin replacement by phosphatidylglycerol in a cardiolipin-lacking yeast respiratory supercomplex. https://doi.org/10.1038/s41467-023-38441-5Saccharomyces cerevisiae
Pavluch 2023 Sci Rep2023Pavluch V, Engstová H, Špačková J, Ježek P (2023) Deficiency of transcription factor Nkx6.1 does not prevent insulin secretion in INS-1E cells. https://doi.org/10.1038/s41598-023-27985-7RatIslet cell;pancreas;thymus
Inoue 2023 Sci Rep2023Inoue R, Miura M, Yanai S, Nishimune H (2023) Coenzyme Q10 supplementation improves the motor function of middle-aged mice by restoring the neuronal activity of the motor cortex. https://doi.org/10.1038/s41598-023-31510-1Nervous system
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Mendoza-Fuentes 2023 PeerJ2023Mendoza-Fuentes A, González-Burgos E, Aparicio Trejo OE, Delgado-Lamas G, Rodríguez-Chávez JL, Pedraza-Chaverri J, Gómez-Serranillos MP, Araiza-Olivera D (2023) The cytotoxicity effect of 7-hydroxy-3,4-dihydrocadalene from Heterotheca inuloides and semisynthetic cadalenes derivates towards breast cancer cells: involvement of oxidative stress-mediated apoptosis. https://doi.org/10.7717/peerj.15586Human
Mathiyazakan 2023 Antimicrob Agents Chemother2023Mathiyazakan V, Wong CF, Harikishore A, Pethe K, Grüber G (2023) Cryo-electron microscopy structure of the Mycobacterium tuberculosis cytochrome bcc:aa3 supercomplex and a novel inhibitor targeting subunit cytochrome cI. Antimicrob Agents Chemother 67:e0153122. https://doi.org/10.1128/aac.01531-22
Cupellini 2023 Photosynth Res2023Cupellini L, Liguori N (2023) Special issue on quantum and classical computational methods in photosynthesis: from the atom to the mesoscale. Photosynth Res 156:1–2. https://doi.org/10.1007/s11120-023-01011-3
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Garcia-Roche 2023 PLoS One2023García-Roche M, Talmón D, Cañibe G, Astessiano AL, Mendoza A, Cassina A, Quijano C, Carriquiry M (2023) Hepatic metabolism of grazing cows of two Holstein strains under two feeding strategies with different levels of pasture inclusion. https://doi.org/10.1371/journal.pone.0290551BovinesLiver
Noone 2023 J Physiol2023Noone J, Damiot A, Kenny H, Chery I, Zahariev A, Normand S, Crampes F, de Glisezinski I, Rochfort KD, Laurens C, Bareille MP, Simon C, Bergouignan A, Blanc S, O'Gorman DJ (2023) The impact of 60 days of -6° head down tilt bed rest on mitochondrial content, respiration and regulators of mitochondrial dynamics. https://doi.org/10.1113/jp284734HumanSkeletal muscle
Devaux 2023 J Comp Physiol B2023Devaux JBL, Hedges CP, Birch N, Herbert N, Renshaw GMC, Hickey AJR (2023) Electron transfer and ROS production in brain mitochondria of intertidal and subtidal triplefin fish (Tripterygiidae). https://doi.org/10.1007/s00360-023-01495-4FishesNervous system
Martell 2023 Acta Neuropathol Commun2023Martell E, Kuzmychova H, Senthil H, Kaul E, Chokshi CR, Venugopal C, Anderson CM, Singh SK, Sharif T (2023) Compensatory cross-talk between autophagy and glycolysis regulates senescence and stemness in heterogeneous glioblastoma tumor subpopulations. https://doi.org/10.1186/s40478-023-01604-yHumanNervous system
Shu 2023 Front Immunol2023Shu P, Liang H, Zhang J, Lin Y, Chen W, Zhang D (2023) Reactive oxygen species formation and its effect on CD4+ T cell-mediated inflammation. Front Immunol 14:1199233. doi: 10.3389/fimmu.2023.1199233
SiouNing 2023 Molecules2023SiouNing AS, Seong TS, Kondo H, Bhassu S (2023) MicroRNA regulation in infectious diseases and its potential as a biosensor in future aquaculture industry: a review. Molecules 28:4357. https://doi.org/10.3390/molecules28114357
Gnaiger 2023 MitoFit CII2023Gnaiger E (2023) Complex II ambiguities ― FADH2 in the electron transfer system. MitoFit Preprints 2023.3.v6. https://doi.org/10.26124/mitofit:2023-0003.v6 - Published 2023-11-22 J Biol Chem (2024)
Gemmink 2023 Mol Metab2023Gemmink A, Daemen S, Wefers J, Hansen J, van Moorsel D, Astuti P, Jorgensen JA, Kornips E, Schaart G, Hoeks J, Schrauwen P, Hesselink MKC (2023) Twenty-four hour rhythmicity in mitochondrial network connectivity and mitochondrial respiration; a study in human skeletal muscle biopsies of young lean and older individuals with obesity. https://doi.org/10.1016/j.molmet.2023.101727HumanSkeletal muscle
Batterson 2023 Physiol Rep2023Batterson PM, McGowan EM, Borowik AK, Kinter MT, Miller BF, Newsom SA, Robinson MM (2023) High-fat diet increases electron transfer flavoprotein synthesis and lipid respiration in skeletal muscle during exercise training in female mice. https://doi.org/10.14814/phy2.15840MouseSkeletal muscle
Sumner 2023 Transl Psychiatry2023Sumner JA, Cleveland S, Chen T, Gradus JL (2023) Psychological and biological mechanisms linking trauma with cardiovascular disease risk. https://doi.org/10.1038/s41398-023-02330-8
Blackwell 2023 Prostate Cancer Prostatic Dis2023Blackwell JEM, Gharahdaghi N, Deane CS, Brook MS, Williams JP, Lund JN, Atherton PJ, Smith K, Wilkinson DJ, Phillips BE (2023) Molecular mechanisms underpinning favourable physiological adaptations to exercise prehabilitation for urological cancer surgery. https://doi.org/10.1038/s41391-023-00774-z
Hosler 2023 Mitochondrion2023Hosler J, Hoang N, Shirey Edwards K (2023) The cyclic lipopeptide micafungin induces rupture of isolated mitochondria by reprograming the mitochondrial inner membrane anion channel. https://doi.org/10.1016/j.mito.2023.05.004RatLiver
Thoral 2023 J Exp Biol2023Thoral E, Roussel D, Gasset E, Dutto G, Queiros Q, McKenzie DJ, Bourdeix JH, Metral L, Saraux C, Teulier L (2023) Temperature-dependent metabolic consequences of food deprivation in the European sardine. https://doi.org/10.1242/jeb.244984FishesSkeletal muscle
Frangos 2023 J Biol Chem2023Frangos SM, DesOrmeaux GJ, Holloway GP (2023) Acidosis attenuates CPT-I supported bioenergetics as a potential mechanism limiting lipid oxidation. https://doi.org/10.1016/j.jbc.2023.105079MouseSkeletal muscle
National Academies of Sciences, Engineering, and Medicine 2023 Navigating infodemics2023National Academies of Sciences, Engineering, and Medicine (2023) Navigating infodemics and building trust during public health emergencies: proceedings of a workshop in brief. National Academies Press, Washington, DC. https://doi.org/10.17226/27188
Shirakawa 2023 Sci Rep2023Shirakawa R, Nakajima T, Yoshimura A, Kawahara Y, Orito C, Yamane M, Handa H, Takada S, Furihata T, Fukushima A, Ishimori N, Nakagawa M, Yokota I, Sabe H, Hashino S, Kinugawa S, Yokota T (2023) Enhanced mitochondrial oxidative metabolism in peripheral blood mononuclear cells is associated with fatty liver in obese young adults. https://doi.org/10.1038/s41598-023-32549-wHumanBlood cells
Luptak 2023 Antioxidants (Basel)2023Ľupták M, Fišar Z, Hroudová J (2023) Different effects of SSRIs, Bupropion, and Trazodone on mitochondrial functions and monoamine oxidase isoform activity. Antioxidants (Basel) 12:1208. https://doi.org/10.3390/antiox12061208PigNervous system
Calabria 2023 Biomedicines2023Calabria E, Muollo V, Cavedon V, Capovin T, Saccenti L, Passarotti F, Ghiotto L, Milanese C, Gelati M, Rudi D, Salvagno GL, Lippi G, Tam E, Schena F, Pogliaghi S (2023) Type 2 diabetes related mitochondrial defects in peripheral mononucleated blood cells from overweight postmenopausal women. https://doi.org/10.3390/biomedicines11010121HumanBlood cells
Sazanov 2023 Biochem J2023Sazanov LA (2023) From the 'black box' to 'domino effect' mechanism: what have we learned from the structures of respiratory complex I. Biochem J 480:319-33. https://doi.org/10.1042/BCJ20210285
Bowering 2023 Front Physiol2023Bowering LR, McArley TJ, Devaux JBL, Hickey AJR, Herbert NA (2023) Metabolic resilience of the Australasian snapper (Chrysophrys auratus) to marine heatwaves and hypoxia. https://doi.org/10.3389/fphys.2023.1215442FishesHeart
Stouth 2023 Autophagy2023Stouth DW, vanLieshout TL, Mikhail AI, Ng SY, Raziee R, Edgett BA, Vasam G, Webb EK, Gilotra KS, Markou M, Pineda HC, Bettencourt-Mora BG, Noor H, Moll Z, Bittner ME, Gurd BJ, Menzies KJ, Ljubicic V (2023) CARM1 drives mitophagy and autophagy flux during fasting-induced skeletal muscle atrophy. https://doi.org/10.1080/15548627.2023.2288528MouseSkeletal muscle
Jaramillo-Jimenez 2023 Mitochondrion2023Jaramillo-Jimenez A, Giil LM, Borda MG, Tovar-Rios DA, Kristiansen KA, Bruheim P, Aarsland D, Barreto GE, Berge RK (2023) Serum TCA cycle metabolites in Lewy bodies dementia and Alzheimer's disease: network analysis and cognitive prognosis. Mitochondrion 71:17-25. https://doi.org/10.1016/j.mito.2023.05.002
Pacifico 2023 Int J Mol Sci2023Pacifico F, Leonardi A, Crescenzi E (2023) Glutamine metabolism in cancer stem cells: a complex liaison in the tumor microenvironment. Int J Mol Sci 24:2337. https://doi.org/10.3390/ijms24032337
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George 2023 Platelets2023George CE, Saunders CV, Morrison A, Scorer T, Jones S, Dempsey NC (2023) Cold stored platelets in the management of bleeding: is it about bioenergetics? Platelets 34:2188969. https://doi.org/10.1080/09537104.2023.2188969Platelet
Horvath 2023 Antioxidants (Basel)2023Horváth T, Sándor L, Baráth B, Donka T, Baráth B, Mohácsi Á, Jász KD, Hartmann P, Boros M (2023) Methane admixture protects liver mitochondria and improves graft function after static cold storage and reperfusion. Antioxidants (Basel) 12:271. https://doi.org/10.3390/antiox12020271RatLiver
Zhang 2023 Nat Commun2023Zhang Y, Fan Y, Hu H, Zhang X, Wang Z, Wu Z, Wang L, Yu X, Song X, Xiang P, Zhang X, Wang T, Tan S, Li C, Gao L, Liang X, Li S, Li N, Yue X, Ma C (2023) ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury. https://doi.org/10.1038/s41467-023-43439-0MouseLiver
Sharma 2023 Biosci Biotechnol Biochem2023Sharma S, Zhang X, Azhar G, Patyal P, Verma A, Kc G, Wei JY (2023) Valine improves mitochondrial function and protects against oxidative stress. https://doi.org/10.1093/bbb/zbad169MouseSkeletal muscle
Oliveira 2023 MitoFit Spotlight2023Oliveira MF, Aveiro Y, Couto-Lima CA (2023) A navigation chart to avoid turbulence in Drosophila mitochondrial research. MitoFit Preprints 2023.7. https://doi.org/10.26124/mitofit:2023-0007 — 2023-11-06 published in Bioenerg Commun 2023.4.Drosophila
Nastasi 2023 J Inorg Biochem2023Nastasi MR, Borisov VB, Forte E (2023) The terminal oxidase cytochrome bd-I confers carbon monoxide resistance to Escherichia coli cells. https://doi.org/10.1016/j.jinorgbio.2023.112341
Robertson 2023 J Cell Sci2023Robertson GL, Riffle S, Patel M, Bodnya C, Marshall A, Beasley HK, Garza-Lopez E, Shao J, Vue Z, Hinton A, Stoll MS, de Wet S, Theart RP, Chakrabarty RP, Loos B, Chandel NS, Mears JA, Gama V (2023) DRP1 mutations associated with EMPF1 encephalopathy alter mitochondrial membrane potential and metabolic programs. https://doi.org/10.1242/jcs.260370HumanFibroblast
Strogulski 2023 J Neurochem2023Strogulski NR, Portela LV, Polster BM, Loane DJ (2023) Fundamental neurochemistry review: microglial immunometabolism in traumatic brain injury. https://doi.org/10.1111/jnc.15959
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Ali 2023 Trends Cell Biol2023Ali ES, Ben-Sahra I (2023) Regulation of nucleotide metabolism in cancers and immune disorders. Trends Cell Biol 33:950-66. https://doi.org/10.1016/j.tcb.2023.03.003
Mancilla 2023 Physiol Rep2023Mancilla R, Pava-Mejia D, van Polanen N, de Wit V, Bergman M, Grevendonk L, Jorgensen J, Kornips E, Hoeks J, Hesselink MKC, Schrauwen-Hinderling VB (2023) Invasive and noninvasive markers of human skeletal muscle mitochondrial function. https://doi.org/10.14814/phy2.15734HumanSkeletal muscle
Shang 2023 Oncotarget2023Shang E, Nguyen TTT, Westhoff MA, Karpel-Massler G, Siegelin MD (2023) Targeting cellular respiration as a therapeutic strategy in glioblastoma. Oncotarget 14:419-25. https://doi.org/10.18632/oncotarget.28424
Kunst 2023 Biomedicines2023Kunst C, Schmid S, Michalski M, Tümen D, Buttenschön J, Müller M, Gülow K (2023) The influence of gut microbiota on oxidative stress and the immune system. Biomedicines 11:1388. https://doi.org/10.3390/biomedicines11051388
Pena-Corona 2023 Front Pharmacol2023Peña-Corona SI, Hernández-Parra H, Bernal-Chávez SA, Mendoza-Muñoz N, Romero-Montero A, Del Prado-Audelo ML, Cortés H, Ateşşahin DA, Habtemariam S, Almarhoon ZM, Abdull Razis AF, Modu B, Sharifi-Rad J, Leyva-Gómez G (2023) Neopeltolide and its synthetic derivatives: a promising new class of anticancer agents. Front Pharmacol 14:1206334. https://doi.org/10.3389/fphar.2023.1206334
Hoogstraten 2023 Arch Toxicol2023Hoogstraten CA, Jacobs MME, de Boer G, van de Wal MAE, Koopman WJH, Smeitink JAM, Russel FGM, Schirris TJJ (2023) Metabolic impact of genetic and chemical ADP/ATP carrier inhibition in renal proximal tubule epithelial cells. https://doi.org/10.1007/s00204-023-03510-7HumanKidney
Silva Dias Vieira 2023 PLoS Negl Trop Dis2023Silva Dias Vieira C, Pinheiro Aguiar R, de Almeida Nogueira NP, Costa Dos Santos Junior G, Paes MC (2023) Glucose metabolism sustains heme-induced Trypanosoma cruzi epimastigote growth in vitro. https://doi.org/10.1371/journal.pntd.0011725Protists
Cruz-Gregorio 2023 Phytother Res2023Cruz-Gregorio A, Aranda-Rivera AK, Aparicio-Trejo OE, Medina-Campos ON, Sciutto E, Fragoso G, Pedraza-Chaverri J (2023) α-Mangostin induces oxidative damage, mitochondrial dysfunction, and apoptosis in a triple-negative breast cancer model. https://doi.org/10.1002/ptr.7812MouseEndothelial;epithelial;mesothelial cell
Mioc 2023 Molecules2023Mioc M, Mioc A, Racoviceanu R, Ghiulai R, Prodea A, Milan A, Barbu Tudoran L, Oprean C, Ivan V, Șoica C (2023) The antimelanoma biological assessment of triterpenic acid functionalized gold nanoparticles. https://doi.org/10.3390/molecules28010421HumanEndothelial;epithelial;mesothelial cell
Kienzle 2023 BMC Biol2023Kienzle L, Bettinazzi S, Choquette T, Brunet M, Khorami HH, Jacques JF, Moreau M, Roucou X, Landry CR, Angers A, Breton S (2023) A small protein coded within the mitochondrial canonical gene nd4 regulates mitochondrial bioenergetics. https://doi.org/10.1186/s12915-023-01609-yHumanHEK
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Sadri 2023 Function (Oxf)2023Sadri S, Zhang X, Audi SH, Cowley AW Jr, Dash RK (2023) Computational modeling of substrate-dependent mitochondrial respiration and bioenergetics in the heart and kidney cortex and outer medulla. Function (Oxf) 4:zqad038. https://doi.org/10.1093/function/zqad038RatHeart
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Faria 2023 Pharmaceutics2023Faria R, Boisguérin P, Sousa Â, Costa D (2023) Delivery systems for mitochondrial gene therapy: a review. Pharmaceutics 15:572. https://doi.org/10.26124/mitofit:2023-0003.v610.3390/pharmaceutics15020572
Verma 2023 Int J Mol Sci2023Verma A, Azhar G, Zhang X, Patyal P, Kc G, Sharma S, Che Y, Wei JY (2023) P. gingivalis-LPS induces mitochondrial dysfunction mediated by neuroinflammation through oxidative stress. Int J Mol Sci 24:950. https://doi.org/10.3390/ijms24020950HumanEndothelial;epithelial;mesothelial cell
Dias 2023 Biofactors2023Dias C, Fernandes E, Barbosa RM, Laranjinha J, Ledo A (2023) Astrocytic aerobic glycolysis provides lactate to support neuronal oxidative metabolism in the hippocampus. https://doi.org/10.1002/biof.1951RatNervous system
Stampley 2023 Physiol Rep2023Stampley JE, Cho E, Wang H, Theall B, Johannsen NM, Spielmann G, Irving BA (2023) Impact of maximal exercise on immune cell mobilization and bioenergetics. https://doi.org/10.14814/phy2.15753HumanBlood cells
Solhaug 2023 Cytotechnology2023Solhaug A, Gjessing M, Sandvik M, Eriksen GS (2023) The gill epithelial cell lines RTgill-W1, from Rainbow trout and ASG-10, from Atlantic salmon, exert different toxicity profiles towards rotenone. Cytotechnology 75:63-75. https://doi.org/10.1007/s10616-022-00560-0
National Academies of Sciences, Engineering, and Medicine 2023 Quantum information2023National Academies of Sciences, Engineering, and Medicine (2023) Advancing chemistry and quantum information science: an assessment of research opportunities at the interface of chemistry and quantum information science in the United States. National Academies Press, Washington, DC. https://doi.org/10.17226/26850
Lu 2023 Explor Res Hypothesis Med2023Lu F (2023) Hypothetical hydrogenase activity of human mitochondrial Complex I and its role in preventing cancer transformation. Explor Res Hypothesis Med 8:280-5. https://doi.org/10.14218/ERHM.2022.00083
Zvejniece 2023 Biomed Pharmacother2023Zvejniece L, Svalbe B, Vavers E, Ozola M, Grinberga S, Gukalova B, Sevostjanovs E, Liepinsh E, Dambrova M (2023) Decreased long-chain acylcarnitine content increases mitochondrial coupling efficiency and prevents ischemia-induced brain damage in rats.Rat
Donnelly 2023 MitoFit2023Donnelly C, Komlódi T, Cecatto C, Cardoso LHD, Compagnion AC, Matera A, Tavernari D, Zanou N, Kayser B, Gnaiger E, Place N (2023) Functional hypoxia reduces mitochondrial calcium uptake. MitoFit Preprints 2023.2. https://doi.org/10.26124/mitofit:2023-0002 — 2024-11-17 published in Redox Biol.Human
Mouse		Skeletal muscle
Heart
Nervous system
Other cell lines
Jezek 2023 Antioxid Redox Signal2023Ježek P, Jabůrek M, Holendová B, Engstová H, Dlasková A (2023) Mitochondrial cristae morphology reflecting metabolism, superoxide formation, redox homeostasis, and pathology. Antioxid Redox Signal 39:635–83. https://doi.org/10.1089/ars.2022.0173
Oliveira 2023 J Biol Chem2023Oliveira AG, Oliveira LD, Cruz MV, Guimarães DSPSF, Lima TI, BC Santos-Fávero, Luchessi AD, BA Pauletti, Leme AP, Bajgelman MC, Afonso J, Regitano LCA, Carvalho HF, Carneiro EM, Kobarg J, Perissi V, Auwerx J, Silveira LR (2023) Interaction between poly-A binding protein PABPC4 and nuclear receptor corepressor NCoR1 modulates a metabolic stress response. https://doi.org/10.1016/j.jbc.2023.104702
Golomb 2023 Sci Rep2023Golomb BA, Sanchez Baez R, Schilling JM, Dhanani M, Fannon MJ, Berg BK, Miller BJ, Taub PR, Patel HH (2023) Mitochondrial impairment but not peripheral inflammation predicts greater Gulf War illness severity. https://doi.org/10.1038/s41598-023-35896-wHumanSkeletal muscle
Sundaram 2023 Cell Metab2023Sundaram VK, Schütza V, Schröter NH, Backhaus A, Bilsing A, Joneck L, Seelbach A, Mutschler C, Gomez-Sanchez JA, Schäffner E, Sánchez EE, Akkermann D, Paul C, Schwagarus N, Müller S, Odle A, Childs G, Ewers D, Kungl T, Sitte M, Salinas G, Sereda MW, Nave KA, Schwab MH, Ost M, Arthur-Farraj P, Stassart RM, Fledrich R (2023) Adipo-glial signaling mediates metabolic adaptation in peripheral nerve regeneration. https://doi.org/10.1016/j.cmet.2023.10.017MouseNervous system
Kim 2023 bioRxiv2023Kim Y, Li C, Gu C, Tycksen E, Puri A, Pietka TA, Sivapackiam J, Fang Y, Kidd K, Park SJ, Johnson BG, Kmoch S, Duffield JS, Bleyer AJ, Jackrel ME, Urano F, Sharma V, Lindahl M, Chen YM (2023) MANF stimulates autophagy and restores mitochondrial homeostasis to treat toxic proteinopathy. https://doi.org/10.1101/2023.01.10.523171MouseEndothelial;epithelial;mesothelial cell
Janz 2023 Mol Metab2023Janz A, Walz K, Cirnu A, Surjanto J, Urlaub D, Leskien M, Kohlhaas M, Nickel A, Brand T, Nose N, Wörsdörfer P, Wagner N, Higuchi T, Maack C, Dudek J, Lorenz K, Klopocki E, Ergün S, Duff HJ, Gerull B (2023) Mutations in DNAJC19 cause altered mitochondrial structure and increased mitochondrial respiration in human iPSC-derived cardiomyocytes. https://doi.org/10.1016/j.molmet.2023.101859HumanHeLa
AlgaEurope 2022 Rome IT2022-12-13
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Rome, IT, 2022 Dec 13-15. AlgaEurope 2022.
MiPNet27.10 IOC156 Ramat Gan IL2022-11-28
O2k-Network
Ramat Gan IL, 2022 Nov 28-30 Oroboros O2k-Workshop on high-resolution respirometry (HRR), IOC156.
FAT4BRAIN 4th Online ESR Workshop2022-11-25
FAT4BRAIN
Virtual, 2022 November 25. FAT4BRAIN 4th Online ESR Workshop - WIDESPREAD PROJECT.
AussieMit 2022 Sydney AU2022-11-16Sydney, AU, 2022 Nov 16-18. AussieMit 2022 7th biennial Australian conference for mitochondrial research.
Charles L. Hoppel Prize for Outstanding Contributions in Mitochondrial Research 20222022-11-14Cleveland, OH , 2022 Nov 14. The Charles L. Hoppel Prize for Outstanding Contributions in Mitochondrial Research.
Cell Symposia 2022 Seville ES2022-11-06
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Seville, ES, 2022 Nov 6-8. Cell Symposia: Multifaceted Mitochondria.
MiPNet26.14 Oxia2022-10-31
O2k-Manual
Oxia - HyperOxia to HypOxia.
13th Targeting Mitochondria Congress 2022 Berlin DE2022-10-26Berlin, DE, 2022 Oct 26-28. 13th Targeting Mitochondria Congress
CRUK Beatson Institute Workshop 2022 Glasgow UK2022-10-24Glasgow, UK, 2022 Oct 24-25. CRUK Beatson Institute Workshop - Problems in the Powerhouse: Mitochondrial Dysfunction in Cancer.
FAT4BRAIN Symposium Jena DE2022-10-20
FAT4BRAIN
Jena DE, 2022 October 20-21. FAT4BRAIN Symposium - Long COVID and acetylcarnitines: From preclinical models to clinical applications and translation potential
MiPNet27.09 FAT4BRAIN O2k-Workshop Schroecken AT2022-10-03
O2k-Workshops.png
Schroecken AT, 2022 Oct 03-08. FAT4BRAIN O2k-Workshop on high-resolution respirometry (HRR), part of IOC155.
MiPNet27.04 IOC155 Schroecken AT2022-10-03
O2k-Workshops.png
Schroecken AT, 2022 Oct 03-08. Oroboros O2k-Workshop on high-resolution respirometry (HRR), IOC155.
MiPNet27.05 Schroecken BEC tutorial-Living Communications pmP2022-09-30
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Schroecken AT, 2022 Sep 30-Oct 03. BEC tutorial-Living Communications: pmF to pmP — pre IOC155.
BMT 2022 Innsbruck AT2022-09-28Innsbruck, AT, 2022 Sep 28-30. Aviso: BMT 2022 - Joint Annual Conference of the Austrian, German and Swiss Societies for Biomedical Engineering
EMBO-FEBS Lecture Course 2022 Budva ME2022-09-27
EMBO-FEBS Lecture Course
Budva ME, 2022 Sep 27 - October 01. EMBO-FEBS Lecture Course 'Mitochondria in life, death and disease'.
MiPNet27.06 Prague BEC tutorial-Living Communications pmF2022-09-22
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Prague CZ, 2022 Sep 22. BEC tutorial-Living Communications: pmF — pre EMC2022 Prague.
EMC2022 Prague CZ2022-09-22Prague CZ, 2022 Sep 22-26. EMC 2022 49th European Muscle Conference
The 77th Japanese Society of Physical Fitness and Sports Medicine 2022 Tochigi JP2022-09-21Tochigi JP, 2022 Sep 21-23. The 77th Japanese Society of Physical Fitness and Sports Medicine
MiPNet27.08 Innsbruck BEC tutorial-Living Communications pmF2022-09-19
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Innsbruck AT, 2022 Sep 19. BEC tutorial-Living Communications: pmF
Europhysiology 2022 Copenhagen DK2022-09-16Copenhagen, DK. 2022 Sep 16-18, Europhysiology 2022.
EBEC2022 Aix-en-Provence FR2022-08-20
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Aix-en-Provence, FR, 2022 August 20-25. 21st European Bioenergetics Conference.
MiPNet27.07 Sample Holder2022-08-09
O2k-Manual
Sample Holder.
MiPNet27.03 IOC154 Innsbruck AT2022-08-01
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Innsbruck AT, 2022 Aug 01-05. O2k-Coaching Days - O2k-FluoRespirometer and NextGen-O2k, IOC154.
5th Academic Symposium of Metabolic Biology Branch of Chinese Biophysical Society 2022 Zunyi CN2022-07-26Zunyi, CN, 2022 Jul 26-29. 5th Academic Symposium of Metabolic Biology Branch of Chinese Biophysical Society.
MiPNet26.13 NextGen-O2k manual2022-07-25
O2k-Manual
NextGen-O2k manual
16th International Conference on Mitochondrial Medicine for Neurodegenerative Diseases 2022 Stockholm SE2022-07-12Stockholm, SE, 2022 July 12-13. ICMMND 2022: 16th International Conference on Mitochondrial Medicine for Neurodegenerative Diseases
FEBS 2022 Mutters AT2022-07-04
FEBS
Mutters, AT. 2022 Jul 04-07, 2nd FEBS Workshop on Ageing and Regeneration.
MiPNet27.02 IOC153 Innsbruck AT2022-07-01
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Innsbruck AT, 2022 Jul 01-02. NextGen-O2k All-in-one Demo Workshop IOC153.
Bioblast 20222022-06-29BEC.png Innsbruck, AT, 2022 Jun 29 - 30. Bioblast 2022: BEC Inaugural Conference. https://doi.org/10.26124/bec:2022-0001
UMDF Mitochondrial Medicine 2022 Phoenix AZ US2022-06-08
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Phoenix AZ, US, 2022 Jun 08-11 . Mitochondrial Medicine.
ESCI 2022 Bari IT2022-06-08
18-109-11.
Bari, IT, 2022 Jun 8-10. 56th Annual Scientific Meeting of the European Society for Clinical Investigation, ESCI 2022.
Long Night of Research 2022 Innsbruck AT2022-05-20
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Innsbruck, AT, 2022 May 20. Oroboros at Long Night of Research, CCB. The diagnostic bioenergetic report – a milestone on the way to mitochondrial fitness and physical well-being.
Research to Practice 2022 Virtual2022-05-19Virtual, 2021 May 19-21. Research to Practice 2022
MiPNet26.12 NextGen-O2k: NADH-Module2022-05-17
O2k-Manual
NextGen-O2k: NADH-Module manual
MiPNet27.01 IOC152 Hamburg DE2022-05-14
Oroboros Instruments
Hamburg DE, 2022 May 14. Oroboros O2k-Lunch Workshop: Continuous monitoring of mitochondrial Coenzyme Q redox state integrated in high-resolution respirometry, IOC152 at 10th Conference of the International Coenzyme Q10 Association 2022 Hamburg DE.
10th Conference of the International Coenzyme Q10 Association 2022 Hamburg DE2022-05-12Hamburg, DE, 2022 May 12-15. 10th Conference of the International Coenzyme Q10 Association
FAT4BRAIN Workshop IOC151 Innsbruck AT2022-05-02
FAT4BRAIN
Innsbruck, AT, 2022 May 2-3. FAT4BRAIN Workshop IOC 151 on mitochondrial function in CNS-related applications: from pre-clinical to clinical studies
MiPNet11.05 imt-pti-pce2022-04-10
O2k-Protocols
Isolated mitochondria or permeabilized tissues and cells.
VASCage 2022 Innsbruck AT2022-04-05Innsbruck, AT, 2022 April 05. VASCage - Vascular and Stroke Research Partnering
Mitochondrial Communications Serial Webinar 4 2022 Virtual2022-03-30Virtual, 2022 March 30. Mitochondrial Communications Serial Webinar 4 2022
Padua Days 2022 Padua IT2022-03-30Padua, IT, 2022 Mar 30 - Apr 02. Padua Days on Myology & Mobility Medicine (PDM3)
MiPNet22.10 MiR05-Kit2022-03-03
O2k-Manual
Mitochondrial Respiration Medium - MiR05-Kit.
MiPNet08.16 pH calibration2022-03-01
O2k-Manual
Laboratory protocol: pH measurement and temperature dependence of pH.
FAT4BRAIN 3rd Online ESR Workshop2022-02-25
FAT4BRAIN
Virtual, 2022 February 25. FAT4BRAIN 3rd Online ESR Workshop - WIDESPREAD PROJECT.
Mitochondria-Targeted Drug Development 2022 Boston US2022-02-22
Mitochondria Targeted Therapeutics
Boston, MA US, 2022 Feb 22-24. 2nd Annual Mitochondria-Targeted Drug Development - Overcome the Challenge of Treating Unmet Medical Needs Caused by Mitochondrial Dysfunction
Crislip 2022 Biomolecules2022Crislip GR, Wohlgemuth SE, Wolff CA, Gutierrez-Monreal MA, Douglas CM, Ebrahimi E, Cheng KY, Masten SH, Barral D, Bryant AJ, Esser KA, Gumz ML (2022) Apparent absence of BMAL1-dependent skeletal muscle-kidney cross talk in mice. https://doi.org/10.3390/biom12020261MouseKidney
Crowder 2022 Islets2022Crowder JJ, Zeng Z, Novak AN, Alves NJ, Linnemann AK (2022) Stabilization protects islet integrity during respirometry in the Oroboros Oxygraph-2K analyzer. Islets 14:128-38.MouseIslet cell;pancreas;thymus
Pallag 2022 Int J Mol Sci2022Pallag G, Nazarian S, Ravasz D, Bui D, Komlódi T, Doerrier C, Gnaiger E, Seyfried TN, Chinopoulos C (2022) Proline oxidation supports mitochondrial ATP production when Complex I is inhibited. https://doi.org/10.3390/ijms23095111MouseLiver
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Wang 2022 Transl Cancer Res2022Wang B, Liu B, Luo Q, Sun D, Li H, Zhang J, Jin X, Cheng X, Niu J, Yuan Q, Chen Y (2022) PANK1 associates with cancer metabolism and immune infiltration in clear cell renal cell carcinoma: a retrospective prognostic study based on the TCGA database. https://doi.org/10.21037/tcr-22-1488HumanKidney
Endothelial;epithelial;mesothelial cell
Formiga-Jr 2022 J Vis Exp2022Formiga-Jr MA, Camacho-Pereira J (2022) Assessing mitochondrial function in sciatic nerve by high-resolution respirometry. https://doi.org/10.3791/63690MouseNervous system
Melin 2022 JHEP Rep2022Melin N, Yarahmadov T, Sanchez-Taltavull D, Birrer FE, Brodie TM, Petit B, Felser A, Nuoffer JM, Montani M, Vozenin MC, Herrmann E, Candinas D, Aebersold DM, Stroka D (2022) A new mouse model of radiation-induced liver disease reveals mitochondrial dysfunction as an underlying fibrotic stimulus. https://doi.org/10.1016/j.jhepr.2022.100508MouseLiver
Markovic 2022 Biomedicines2022Marković A, Tauchmannová K, Šimáková M, Mlejnek P, Kaplanová V, Pecina P, Pecinová A, Papoušek F, Liška F, Šilhavý J, Mikešová J, Neckář J, Houštěk J, Pravenec M, Mráček T (2022) Genetic complementation of ATP synthase deficiency due to dysfunction of TMEM70 assembly factor in rat. https://doi.org/10.3390/biomedicines10020276RatHeart
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Timon-Gomez 2022 Elife2022Timón-Gómez A, Scharr AL, Wong NY, Ni E, Roy A, Liu M, Chau J, Lampert JL, Hireed H, Kim NS, Jan M, Gupta AR, Day RW, Gardner JM, Wilson RJA, Barrientos A, Chang AJ (2022) Tissue-specific mitochondrial HIGD1C promotes oxygen sensitivity in carotid body chemoreceptors. https://doi.org/10.7554/elife.78915
Kravchuk 2022 Nature2022Kravchuk V, Petrova O, Kampjut D, Wojciechowska-Bason A, Breese Z, Sazanov L (2022) A universal coupling mechanism of respiratory complex I. Nature 609:808-14. https://doi.org/10.1038/s41586-022-05199-7. Erratum in: Nature. 2022;611:E9.Eubacteria
Smith 2022 J Pineal Res2022Smith KLM, Swiderska A, Lock MC, Graham L, Iswari W, Choudhary T, Thomas D, Kowash HM, Desforges M, Cottrell EC, Trafford AW, Giussani DA, Galli GLJ (2022) Chronic developmental hypoxia alters mitochondrial oxidative capacity and reactive oxygen species production in the fetal rat heart in a sex-dependent manner. https://doi.org/10.1111/jpi.12821RatHeart
Donnelly 2022 BEC2022Donnelly C, Schmitt S, Cecatto C, Cardoso LHD, Komlódi T, Place N, Kayser B, Gnaiger E (2022) The ABC of hypoxia – what is the norm. Bioenerg Commun 2022.12.v2. https://doi.org/10.26124/bec:2022-0012.v2
Gentile 2022 FASEB J2022Gentile A, Magnacca N, de Matteis R, Moreno M, Cioffi F, Giacco A, Lanni A, de Lange P, Senese R, Goglia F, Silvestri E, Lombardi A (2022) Ablation of uncoupling protein 3 affects interrelated factors leading to lipolysis and insulin resistance in visceral white adipose tissue. https://doi.org/10.1096/fj.202101816rrMouseFat
Balbaisi 2022 BEC2022Balbaisi A, Stiban J (2022) Barth syndrome: a genetic ailment with a lipid component and bioenergetic ramifications. Bioenerg Commun 2022.5. https://doi.org/10.26124/bec:2022-0005Human
Wang 2022 Redox Biol2022Wang P, Cui Y, Liu Y, Li Z, Bai H, Zhao Y, Chang YZ (2022) Mitochondrial ferritin alleviates apoptosis by enhancing mitochondrial bioenergetics and stimulating glucose metabolism in cerebral ischemia reperfusion. https://doi.org/10.1016/j.redox.2022.102475MouseNervous system
Peng 2022 Front Oncol2022Peng M, Huang Y, Zhang L, Zhao X, Hou Y (2022) Targeting mitochondrial oxidative phosphorylation eradicates acute myeloid leukemic stem cells. Front Oncol 12:899502. https://doi.org/10.3389/fonc.2022.899502
Dobrowolski 2022 Mol Genet Metab2022Dobrowolski SF, Phua YL, Sudano C, Spridik K, Zinn PO, Wang Y, Bharathi S, Vockley J, Goetzman E (2022) Comparative metabolomics in the Pahenu2 classical PKU mouse identifies cerebral energy pathway disruption and oxidative stress. https://doi.org/10.1016/j.ymgme.2022.03.004
Barath 2022 Int J Mol Sci2022Baráth B, Jász DK, Horváth T, Baráth B, Maróti G, Strifler G, Varga G, Sándor L, Perényi D, Tallósy S, Donka T, Jávor P, Boros M, Hartmann P (2022) Mitochondrial side effects of surgical prophylactic antibiotics Ceftriaxone and Rifaximin lead to bowel mucosal damage. Int J Mol Sci 23:5064. https://doi.org/10.3390/ijms23095064RatLiver
Galambo 2022 Curr Res Physiol2022Galambo D, Bergdahl A (2022) Physiological levels of cardiolipin acutely affect mitochondrial respiration in vascular smooth muscle cells. https://doi.org/10.1016/j.crphys.2022.100097MouseOther cell lines
Patyal 2022 Int J Mol Sci2022Patyal P, Nguyen B, Zhang X, Azhar G, Ameer FS, Verma A, Crane J, Kc G, Che Y, Wei JY (2022) Rho/SRF inhibitor modulates mitochondrial functions. https://doi.org/10.3390/ijms231911536MouseSkeletal muscle
Yuan 2022 Oxid Med Cell Longev2022Yuan Q, Zeng ZL, Yang S, Li A, Zu X, Liu J (2022) Mitochondrial stress in metabolic inflammation: modest benefits and full losses. Oxid Med Cell Longev 2022:8803404. https://doi.org/10.1155/2022/8803404
Kullmann 2022 JCI Insight2022Kullmann S, Goj T, Veit R, Fritsche L, Wagner L, Schneeweiss P, Hoene M, Hoffmann C, Machann J, Niess A, Preissl H, Birkenfeld AL, Peter A, Häring HU, Fritsche A, Moller A, Weigert C, Heni M (2022) Exercise restores brain insulin sensitivity in sedentary adults who are overweight and obese. https://doi.org/10.1172/jci.insight.161498
Wipf 2022 J Huntingtons Dis2022Wipf P, Polyzos AA, McMurray CT (2022) A double-pronged sword: XJB-5-131 is a suppressor of somatic instability and toxicity in Huntington's disease. J Huntingtons Dis 11:3-15. https://doi.org/10.3233/JHD-210510
Quast 2022 Basic Res Cardiol2022Quast C, Kober F, Becker K, Zweck E, Hoffe J, Jacoby C, Flocke V, Gyamfi-Poku I, Keyser F, Piayda K, Erkens R, Niepmann S, Adam M, Baldus S, Zimmer S, Nickenig G, Grandoch M, Bönner F, Kelm M, Flögel U (2022) Multiparametric MRI identifies subtle adaptations for demarcation of disease transition in murine aortic valve stenosis. https://doi.org/10.1007/s00395-022-00936-5MouseHeart
Serna 2022 MitoFit2022Serna JDC, Ramos VM, Cabral-Costa JV, Vilas-Boas EA, Amaral AG, Ohya G, da Silva CCC, Kowaltowski AJ (2022) Measuring mitochondrial Ca2+ efflux in isolated mitochondria and permeabilized cells. https://doi.org/10.26124/mitofit:2022-0021 — 2022-07-28 published in Bioenerg Commun 2022.7.Human
Mouse		Liver
Other cell lines
Rios-Morales 2022 Biochim Biophys Acta Mol Basis Dis2022Rios-Morales M, Vieira-Lara MA, Homan E, Langelaar-Makkinje M, Gerding A, Li Z, Huijkman N, Rensen PCN, Wolters JC, Reijngoud DJ, Bakker BM (2022) Butyrate oxidation attenuates the butyrate-induced improvement of insulin sensitivity in myotubes. https://doi.org/10.1016/j.bbadis.2022.166476MouseSkeletal muscle
Martino 2022 Cell Rep2022Martino MR, Gutiérrez-Aguilar M, Yiew NKH, Lutkewitte AJ, Singer JM, McCommis KS, Ferguson D, Liss KHH, Yoshino J, Renkemeyer MK, Smith GI, Cho K, Fletcher JA, Klein S, Patti GJ, Burgess SC, Finck BN (2022) Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids. https://doi.org/10.1016/j.celrep.2022.110733
Benit 2022 Biomedicines2022Bénit P, Goncalves J, El Khoury R, Rak M, Favier J, Gimenez-Roqueplo AP, Rustin P (2022) Succinate dehydrogenase, succinate, and superoxides: a genetic, epigenetic, metabolic, environmental explosive crossroad. Biomedicines 10:1788. https://doi.org/10.3390/biomedicines10081788
Soares 2022 J Cachexia Sarcopenia Muscle2022Soares MN, Eggelbusch M, Naddaf E, Gerrits KHL, van der Schaaf M, van den Borst B, Wiersinga WJ, van Vugt M, Weijs PJM, Murray AJ, Wüst RCI (2022) Skeletal muscle alterations in patients with acute Covid-19 and post-acute sequelae of Covid-19. J Cachexia Sarcopenia Muscle. doi: 10.1002/jcsm.12896HumanSkeletal muscle
Scrima 2022 Stem Cell Res Ther2022Scrima R, Agriesti F, Pacelli C, Piccoli C, Pucci P, Amoresano A, Cela O, Nappi L, Tataranni T, Mori G, Formisano P, Capitanio N (2022) Myoglobin expression by alternative transcript in different mesenchymal stem cells compartments. https://doi.org/10.1186/s13287-022-02880-6HumanStem cells
LaMoia 2022 Proc Natl Acad Sci U S A2022LaMoia TE, Butrico GM, Kalpage HA, Goedeke L, Hubbard BT, Vatner DF, Gaspar RC, Zhang XM, Cline GW, Nakahara K, Woo S, Shimada A, Hüttemann M, Shulman GI (2022) Metformin, phenformin, and galegine inhibit complex IV activity and reduce glycerol-derived gluconeogenesis. Proc Natl Acad Sci U S A 119:e2122287119. https://doi.org/10.1073/pnas.2122287119
Lopes 2022 Int J Mol Sci2022Lopes JA, Collino F, Rodrigues-Ferreira C, Sampaio LDS, Costa-Sarmento G, Wendt CHC, Almeida FP, Miranda KR, Kasai-Brunswick TH, Lindoso RS, Vieyra A (2022) Early effects of extracellular vesicles secreted by adipose tissue mesenchymal cells in renal ischemia followed by reperfusion: mechanisms rely on a decrease in mitochondrial anion superoxide production. https://doi.org/10.3390/ijms23062906HumanKidney
Azzi 2022 Antioxidants (Basel)2022Azzi A (2022) Oxidative stress: What is it? Can it be measured? Where is it located? Can it be good or bad? Can it be prevented? Can it be cured? Antioxidants (Basel) 11:1431. https://doi.org/10.3390/antiox11081431
Wu 2022 Chem Sci2022Wu Y, Li Y, Lv G, Bu W (2022) Redox dyshomeostasis strategy for tumor therapy based on nanomaterials chemistry. Chem Sci 13:2202-2217.
Turton 2022 Int J Mol Sci2022Turton N, Cufflin N, Dewsbury M, Fitzpatrick O, Islam R, Watler LL, McPartland C, Whitelaw S, Connor C, Morris C, Fang J, Gartland O, Holt L, Hargreaves IP (2022) The biochemical assessment of mitochondrial respiratory chain disorders. Int J Mol Sci 23:7487. https://doi.org/10.3390/ijms23137487Human
Arbon 2022 Antimicrob Agents Chemother2022Arbon D, Ženíšková K, Šubrtová K, Mach J, Štursa J, Machado M, Zahedifard F, Leštinová T, Hierro-Yap C, Neuzil J, Volf P, Ganter M, Zoltner M, Zíková A, Werner L, Sutak R (2022) Repurposing of MitoTam: Novel anti-cancer drug candidate exhibits potent activity against major protozoan and fungal pathogens. https://doi.org/10.1128/aac.00727-22Protists
Dieter 2022 Int J Mol Sci2022Dieter F, Esselun C, Eckert GP (2022) Redox active α-lipoic acid differentially improves mitochondrial dysfunction in a cellular model of Alzheimer and its control cells. https://doi.org/10.3390/ijms23169186HumanNeuroblastoma
Gupta 2022 PNAS Nexus2022Gupta R, Rhee KY, Beagle SD, Chawla R, Perdomo N, Lockless SW, Lele PP (2022) Indole modulates cooperative protein-protein interactions in the flagellar motor. https://doi.org/10.1093/pnasnexus/pgac035Eubacteria
Narine 2022 Front Cell Neurosci2022Narine M, Colognato H (2022) Current insights into oligodendrocyte metabolism and its power to sculpt the myelin landscape. Front Cell Neurosci 16:892968. https://doi.org/10.3389/fncel.2022.892968.
Zhang 2022 Mol Med Rep2022Zhang J, Sun B, Yang J, Chen Z, Li Z, Zhang N, Li H, Shen L (2022) Comparison of the effect of rotenone and 1‑methyl‑4‑phenyl‑1,2,3,6‑tetrahydropyridine on inducing chronic Parkinson's disease in mouse models. https://doi.org/10.3892/mmr.2022.12607MouseNervous system
Molina-Granada 2022 Commun Biol2022Molina-Granada D, González-Vioque E, Dibley MG, Cabrera-Pérez R, Vallbona-Garcia A, Torres-Torronteras J, Sazanov LA, Ryan MT, Cámara Y, Martí R (2022) Most mitochondrial dGTP is tightly bound to respiratory complex I through the NDUFA10 subunit. Commun Biol 5:620. doi: 10.1038/s42003-022-03568-6HEK
Donnelly 2022 MitoFit Hypoxia2022Donnelly C, Schmitt S, Cecatto C, Cardoso LHD, Komlodi T, Place N, Kayser B, Gnaiger E (2022) The ABC of hypoxia – what is the norm. https://doi.org/10.26124/mitofit:2022-0025.v2 — 2022-11-14 published in Bioenerg Commun 2022.12.
Bon 2022 J Clin Case Rep Stud2022Bon E, Maksimovich NY, Dremza IK (2022) Alendronate-induced nephropathy. J Clin Case Rep Stud 3. https://doi.org/10.31579/2690-8808/108
Spielmann 2022 Mamm Genome2022Spielmann N, Schenkl C, Komlódi T, da Silva-Buttkus P, Heyne E, Rohde J, Amarie OV, Rathkolb B, Gnaiger E, Doenst T, Fuchs H, Gailus-Durner V, de Angelis MH, Szibor M (2022) Knockout of the Complex III subunit Uqcrh causes bioenergetic impairment and cardiac contractile dysfunction. Mamm Genome 10.1007/s00335-022-09973-wMouseHeart
Gonzalez-Franquesa 2022 Redox Biol2022Gonzalez-Franquesa A, Gama-Perez P, Kulis M, Szczepanowska K, Dahdah N, Moreno-Gomez S, Latorre-Pellicer A, Fernández-Ruiz R, Aguilar-Mogas A, Hoffman A, Monelli E, Samino S, Miró-Blanch J, Oemer G, Duran X, Sanchez-Rebordelo E, Schneeberger M, Obach M, Montane J, Castellano G, Chapaprieta V, Sun W, Navarro L, Prieto I, Castaño C, Novials A, Gomis R, Monsalve M, Claret M, Graupera M, Soria G, Wolfrum C, Vendrell J, Fernández-Veledo S, Enríquez JA, Carracedo A, Perales JC, Nogueiras R, Herrero L, Trifunovic A, Keller MA, Yanes O, Sales-Pardo M, Guimerà R, Blüher M, Martín-Subero JI, Garcia-Roves PM (2022) Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue. https://doi.org/10.1016/j.redox.2022.102353MouseSkeletal muscle
Nervous system
Liver
Fat
Betiu 2022 Int J Mol Sci2022Bețiu AM, Noveanu L, Hâncu IM, Lascu A, Petrescu L, Maack C, Elmér E, Muntean DM (2022) Mitochondrial effects of common cardiovascular medications: the good, the bad and the mixed. Int J Mol Sci 23:13653. https://doi.org/10.3390/ijms232113653
Vacurova 2022 Nat Commun2022Vacurova E, Trnovska J, Svoboda P, Skop V, Novosadova V, Reguera DP, Petrezselyová S, Piavaux B, Endaya B, Spoutil F, Zudova D, Stursa J, Melcova M, Bielcikova Z, Werner L, Prochazka J, Sedlacek R, Huttl M, Hubackova SS, Haluzik M, Neuzil J (2022) Mitochondrially targeted tamoxifen alleviates markers of obesity and type 2 diabetes mellitus in mice. https://doi.org/10.1038/s41467-022-29486-zMouseFat
Molinie 2022 Biochim Biophys Acta Bioenerg2022Molinié T, Cougouilles E, David C, Cahoreau E, Portais JC, Mourier A (2022) MDH2 produced OAA is a metabolic switch rewiring the fuelling of respiratory chain and TCA cycle. Biochim Biophys Acta Bioenerg 1863:148532.MouseHeart
Liver
Maklashina 2022 J Biol Chem2022Maklashina E, Iverson TM, Cecchini G (2022) How an assembly factor enhances covalent FAD attachment to the flavoprotein subunit of complex II. J Biol Chem 298:102472. https://doi.org/10.1016/j.jbc.2022.102472Human
Eubacteria
Brun 2022 Plant Direct2022Brun A, Smokvarska M, Wei L, Chay S, Curie C, Mari S (2022) MCO1 and MCO3, two putative ascorbate oxidases with ferroxidase activity, new candidates for the regulation of apoplastic iron excess in Arabidopsis. https://doi.org/10.1002/pld3.463Saccharomyces cerevisiae
Pruuchova 2022 Antioxidants (Basel)2022Průchová P, Gotvaldová K, Smolková K, Alán L, Holendová B, Tauber J, Galkin A, Ježek P, Jabůrek M (2022) Antioxidant role and cardiolipin remodeling by redox-activated mitochondrial Ca2+-independent phospholipase A2γ in the brain.MouseNervous system
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MitoPedia concepts: SUIT protocol, SUIT B, Find 


MitoPedia methods: Respirometry 




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