From Bioblast
- high-resolution terminology - matching measurements at high-resolution
TMRM
Description
TMRM ( tetramethylrhodamine methyl ester) is an extrinsic fluorophore and can be used as a probe to determine changes in mitochondrial membrane potential. TMRM is a lipophilic cations that is accumulated by mitochondria in proportion to ΞΟmt. Upon accumulation of the dye it exhibits a red shift in its absorption and fluorescence emission spectrum. The fluorescence intensity is quenched when the dye is accumulated by mitochondria.
Abbreviation: TMRM
MitoPedia methods:
Fluorometry
For an example of the use of TMRM with mouse liver mitochondria see the discussion page of this entry
