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'''[[About Oroboros]]'''
'''[[About Oroboros]]'''
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:<big><big>'''[http://wiki.oroboros.at/images/4/44/MiPNet14.10_O2k-Top10.pdf Top 10 reasons for Oroboros]'''</big></big>
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[[Image:O2k-Fluorometer.jpg|700px|right|link=http://wiki.oroboros.at/index.php/O2k-FluoRespirometer|O2k-FluoRespirometer]] ย 
[[File:Projects logo.jpg|500px|right|link=http://wiki.oroboros.at/index.php?title=Talk:Zhang_F&action=submit]]
<big><big>'''2017 - a glance at the 25<sup>th</sup> year'''</big></big>
'''Oroboros Instruments''' is strongly engaged in cancer research sending you an alert on the [https://www.uicc.org/what-we-do/convening/world-cancer-day World Cancer Day].
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:* From high-resolution respirometry to [[O2k-FluoRespirometer | High-Resolution FluoRespirometry]]
In the course of cancer progression, reprogramming of cell metabolism points out to '''mitochondrial adjustments to the oncological state or may involve mitochondrial dysfunction'''. '''Metabolism''' and '''mitochondria''' are therefore '''in the focus of research as potential targets for novel anticancer therapies'''.
:* From DatLab 6 to [[MitoPedia: DatLab | DatLab 7]]
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ยป [[O2k-Publications:_Cancer|O2k-Publications on cancer]].
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[[Image:O2k-Fluorometer.jpg|600px|right|link=http://wiki.oroboros.at/index.php/O2k-FluoRespirometer|O2k-FluoRespirometer]]
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<td bgcolor="#B0DAFD" style="width:800px; left:0px;" align="left">'''Mitochondria and cancer'''</td>
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1. Metabolic reprogramming<br>
2. Mitochondrial DNA damage<br>
3. Mitochondrial enzyme deficiency<br>
4. Oxidative stress<br>
5. Altered calcium homeostasis<br>
6. Altered ATP synthesis
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<td bgcolor="#B0DAFD" style="width:800px; left:0px;" align="left">'''High-Resolution FluoRespirometry โ€“ Two in one'''</td>
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<td bgcolor="#FFFFFF" style="width:350px; left:50px;" align="left">Combined measurements
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<td bgcolor="#FFFFFF" style="width:350px; left:50px;" align="left">Applicable to all types of samples
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<td bgcolor="#FFFFFF" style="width:350px; left:50px;" align="left">
1. Mitochondrial respiration<br>
2. Reactive oxygen species production<br>
3. Mitochondrial membrane potential<br>
4. ATP synthesis<br>
5. Calcium uptake<br>
6. Extramitochondrial pH
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1. Intact and permeabilized cells, including blood cells<br>
2. Isolated mitochondria<br>
3. Tissue homogenates<br>
4. Tissue biopsies<br>
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:* '''[[MiR05-Kit]]'''
:* '''MitO2-Kit''' with plasma-membrane permeable succinate and malonate for advanced SUIT protocols with intact cells


:* Exactly '''100''' O2k instruments distributed worldwide this year
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:* '''575''' [[O2k-Network]] labs in 49 countries
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:* More than '''2,500''' [[O2k-Publications]] - ''We apologize if we missed one of yours, and will appreciate if you give us an update.''
<td bgcolor="#B0DAFD" style="width:800px; left:0px;" align="left">'''Marie Skล‚odowska-Curie PhD Projects'''
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[http://bioblast.at/index.php/TRACT TRACT] and [http://bioblast.at/index.php/TRANSMIT TRANSMIT] are projects involving oesophageal and prostate cancer research.
:<big><big>'''ยป [[Oroboros 25 years - since 1992]]'''</big></big>
:<big><big>'''ยป [http://wiki.oroboros.at/images/4/44/MiPNet14.10_O2k-Top10.pdf Top 10 reasons for Oroboros]'''</big></big>
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Revision as of 17:00, 5 February 2018


Top 10 reasons for Oroboros



Projects logo.jpg

Oroboros Instruments is strongly engaged in cancer research sending you an alert on the World Cancer Day.

In the course of cancer progression, reprogramming of cell metabolism points out to mitochondrial adjustments to the oncological state or may involve mitochondrial dysfunction. Metabolism and mitochondria are therefore in the focus of research as potential targets for novel anticancer therapies.

ยป O2k-Publications on cancer.

O2k-FluoRespirometer


Mitochondria and cancer

1. Metabolic reprogramming
2. Mitochondrial DNA damage
3. Mitochondrial enzyme deficiency
4. Oxidative stress
5. Altered calcium homeostasis
6. Altered ATP synthesis


High-Resolution FluoRespirometry โ€“ Two in one
Combined measurements Applicable to all types of samples

1. Mitochondrial respiration
2. Reactive oxygen species production
3. Mitochondrial membrane potential
4. ATP synthesis
5. Calcium uptake
6. Extramitochondrial pH

1. Intact and permeabilized cells, including blood cells
2. Isolated mitochondria
3. Tissue homogenates
4. Tissue biopsies



Marie Skล‚odowska-Curie PhD Projects

TRACT and TRANSMIT are projects involving oesophageal and prostate cancer research.

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