From Bioblast
Description
Uncoupling protein 2 (UCP2) belongs to the gene family of uncoupling proteins. Whereas UCP1 acts as an uncoupler, this may not be the case for UCP2.
Abbreviation: UCP2
MitoPedia topics:
Uncoupler
- UCP2 controls mitochondrial fission in hypothalamic neurons, based on the amount of glucose in the blood, which controls the activity of glucose-excited neurons, and thus regulates blood glucose.[1]
References
- β Toda C, Kim JD, Impellizzeri D, Cuzzocrea S, Liu ZW, Diano S (2016) UCP2 regulates mitochondrial fission and ventromedial nucleus control of glucose responsiveness. Cell 164:872-83.