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Template:SUIT-003 Ce1;ce2Omy;ce3U;ce4Rot;ce5S;ce6Ama

From Bioblast
MitoPedia: SUIT

Steps and respiratory states

Ce1;ce2Omy;ce3U;ce4Rot;ce5S;ce6Ama.png

Step State Pathway Q-junction Comment - Events (E) and Marks (M)
ce1 ROUTINE ce1
  • ROUTINE respiration in the physiological coupling state R. Externally added permeable substrates could contribute to this respiratory state.
ce2Omy L ce1;ce2Omy
  • Non-phosphorylating resting state (LEAK state); LEAK respiration L(n) in the absence of ADP, ATP, AMP (no adenylates).
ce3U E ce1;ce2Omy;ce3U
ce4Rot ROX ce1;ce2Omy;ce3U;ce4Rot
  • Rox is the residual oxygen consumption in the ROX state, due to oxidative side reactions, estimated either after inhibition of CIII (e.g. antimycin A, myxothiazol), CIV (e.g. Cyanide) or in the absence of endogenous fuel-substrates. Rox is subtracted from oxygen flux as a baseline for all respiratory states, to obtain mitochondrial respiration.
Step State Pathway Q-junction Comment - Events (E) and Marks (M)
ce5S ce1;ce2Omy;ce3U;ce4Rot;ce5S
ce6Ama ROX ce1;ce2Omy;ce3U;ce4Rot;ce5S;ce6Ama
  • Rox is the residual oxygen consumption in the ROX state, due to oxidative side reactions, estimated after addition of antimycin A (inhibitor of CIII). Rox is subtracted from oxygen flux as a baseline for all respiratory states, to obtain mitochondrial respiration (mt).
  • Rox is the residual oxygen consumption in the ROX state, due to oxidative side reactions, estimated either after inhibition of CIII (e.g. antimycin A, myxothiazol), CIV (e.g. Cyanide) or in the absence of endogenous fuel-substrates. Rox is subtracted from oxygen flux as a baseline for all respiratory states, to obtain mitochondrial respiration.


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