MiPsummer 2008 Programme
- 12-18 July 2008, Schroecken, Vorarlberg, Austria
- Last update: 2008-07-10
- summer2008_Program.pdf Download MiPsummer Programme [pdf 2.8 MB kB; Update: 2008-07-11]
- Lectures of the MiPsummer School on "Mitochondrial Respiratory Phyisology" provide a balance between an introduction into the basic concepts, advanced methodological and scientific approaches, and specific applications, with a focus on mitochondrial respiratory function linked to the general theme of MiP.
- For addresses of lecturers, see MiPsummer Participants.
- We may consider much of the program more as a workshop than just a lecture course, such that at any time of a lecture questions may be asked or comments be added, as long as we can adhere to the time schedule.
- Day 1: Mitochondrial respiratory capacity, coupling and respiratory control. Programme 1 - Abstracts 1
- Day 2: Basic science and clinical reality 1. Programme 2 - Abstracts 2
- Day 3: Oxygen kinetics of mitochondrial respiration and inhibition by nitric oxide. Programme 3 - Abstracts 3
- Day 4: Mitochondrial membrane potential. Programme 4 - Abstracts 4
- Day 5: Basic science and clinical reality 2. Programme 5 - Abstracts 5
1 - Sunday, 13. July
- Mitochondrial respiratory capacity and respiratory control - Abstracts Day 1
| Chair: Vilma Borutaite (LT), Steven C Hand (US) | ||
| 1-01L | 09:00-10:30 | Erich Gnaiger (Innsbruck, AT) Mitochondrial respiratory control: Electron transport system, oxidative phosphorylation and leak – ETS, OXPHOS and LEAK. Poster 1-01L. |
| 10:30 | Coffee | |
| 1-02L | 11:00-12:30 | Chuck Hoppel (Cleveland, USA) Substrates used in studies of OXPHOS. An application example: The effect of developmental age on mitochondrial function in human skeletal muscle. |
| 13:00 | Lunch | |
| Chair: Dominique Votion (BE), Erich Gnaiger (AT) | ||
| 1-03L | 15:00-16:30 | Rodrigue Rossignol (Bordeaux, FR) Ultrastructure of the mitochondrion and its bearing on function and bioenergetics. |
| Flash presentations of posters: | ||
| 1-04P | 16:30-16:45 | Estelle Hirzel (Basel, CH) Mitochondrial targeting in adipocytes using antioxidant tetrapeptides. :::Communicated by Vilma Borutaite. |
| 1-05P | 16:45-17:00 | Leandro S. da Costa (Rio de Janeiro, BR) Mitochondrial dysfunction in neuroblastoma cells infected with sindbis virus. Communicated by Vilma Borutaite. |
| 1-06P | 17:00-17:15 | René G Feichtinger (Salzburg, AT) Decrease of aerobic mitochondrial energy metabolism in paediatric solid tumors. Communicated by Steven C Hand. |
| 1-07P | 17:15-17:30 | Franz A. Zimmermann (Salzburg, AT) Deficiency of complex I of the respiratory chain in oncocytic tumors. :::Communicated by Chuck Hoppel. |
| 17:30-18:45 | Coffee and Posters | |
| 19:00 | Dinner at Hotel Mohnenfluh | |
| 21:15 | MiPboard Meeting: MiP2009 and beyond (Hotel Mohnenfluh) |
2 - Monday, 14. July
- Membrane potential, coupling, substrates and respiratory control - Abstracts Day 2
| Chair: Hélène Lemieux (AT), Guy C Brown (UK) | ||
| 2-01L | 09:00-10:30 | Vilma Borutaite (Kaunas, LT) Mitochondrial membrane potential: why and how to measure. |
| 10:30 | Coffee | |
| 2-02P | 11:00-11:15 | Patrick Subarsky (Innsbruck, AT) Regulation of oxidative phosphorylation in response to graded uncoupling towards the limit of electron transport capacity. Poster 2-02L Communicated by Guy C Brown. |
| 2-03L | 11:15-12:00 | Dominique-Marie Votion (Liége, BE) Mitochondrial respiration in the equine muscle with high-resolution respirometry: Race horses and a rare myopathy. |
| 2-04L | 12:00-12:45 | Erich Gnaiger (Innsbruck, AT) How are respiratory control ratios interpreted? – Concepts and applications. Poster 2-04L. |
| 13:00 | Lunch | |
| Chair Vilma Borutaite (LT), Chuck Hoppel (US) | ||
| Flash presentations of posters: | ||
| 2-05P | 16:00-16:15 | Olga Panasiuk (Kiev, UA) Different sensitivities of two mitochondrial subpopulations to calcium-induced injury. Communicated by Chuck Hoppel. |
| 2-06P | 16:15-16:30 | José Lumini-Oliveira (Coimbra, PT) Effects of endurance treadmill training on skeletal muscle mitochondrial respiratory function of STZ-treated rats. Communicated by Chuck Hoppel. |
| 2-07P | 16:30-16:45 | Liat Shachnai (Rehovot, IL) MTCH2/MIMP: A novel regulator of mitochondrial function. Communicated by Vilma Borutaite. |
| 16:45–17:45 | Coffee and Posters | |
| 17:45-18:45 | Special interest groups | |
| 19:00 | Dinner at Hotel Mohnenfluh | |
| 21:15-22:15 | Special interest groups |
3 - Tuesday, 15. July
- Gas interactions with mitochondria
| Chair: Dominique Votion (BE), Anthony Hickey (NZ) | ||
| 3-01L | 09:00-10:30 | Guy C Brown (Cambridge, UK) Nitric oxide and other gas interactions with mitochondria. |
| 10:30-10:45 | Questions and suggestions by participants | |
| 10:45-11:45 | Coffee and Posters / Special interest groups | |
| In case of favourable weather conditions: | ||
| 12:00 | MiPsummer Walk to the cheese and wine reception at the Alpmuseum uf m Tannberg; refreshment in the lake Körebersee or at Hotel Körbersee. | |
| Chair: Francesca Scandurra (AT), Steven C Hand (US) | ||
| 3-02L | 17:15-18:00 | Erich Gnaiger (Innsbruck, AT) Do we need a thermodynamics background in bioenergetics and mitochondrial physiology? |
| 3-03D | 18:00-18:45 | Mario Fasching (Innsbruck, AT) Simultaneous high-resolution measurement of pH and oxygen Flux with the Oxygraph-2k (instrument demo). |
| 19:00 | Dinner at Hotel Mohnenfluh. |
4 - Wednesday, 16. July
- Oxygen kinetics of mitochondrial respiration and spectrophotometry - Abstracts Day 4
| Chair: Vilma Borutaite (LT), Guy C Brown (UK) | ||
| 4-01L | 09:00-09:45 | Francesca Scandurra (Innsbruck, AT) Cellular respiration under hypoxia: Mitochondrial oxygen kinetics at steady-state oxygen supply and aerobic-anaerobic transitions. |
| 4-02D | 09:45-11:00 | Natascha Sommer and Thomas Derfuss (Giessen, DE) Simultaneous remission spectrophotometry and high-resolution respirometry. Respiratory control by oxygen and redox states of mitochondrial cytochromes in cells. |
| 11:00 | Coffee and Posters | |
| 4-03L | 11:45-12:45 | Erich Gnaiger (Innsbruck, AT) Competitive and undcompetitive inhibition of cytochrome c oxidase by NO in living cells. |
| 13:00 | Lunch | |
| Heart and skeletal muscle mitochondria | ||
| Chair: Natascha Sommer (DE), Steven C Hand (US) | ||
| 4-04L | 15:00-15:30 | Chuck Hoppel (Cleveland, US) Ischemia-reperfusion injury in heart mitochondria. |
| 4-05L | 15:30-16:00 | Hélène Lemieux (Innsbruck, AT) Mitochondrial dysfunction in pathologies of the human heart and comparison with mitochondrial respiratory control in the mouse heart. |
| Flash presentations of posters: | ||
| 4-06P | 16:00-16:15 | Julie H Rennison (Cleveland, US) High fat fed heart failure animals have enhanced mitochondrial function and acyl-CoA dehydrogenase activities. Communicated by Erich Gnaiger. |
| 4-07P | 16:15-16:30 | Antonina V Pustovidko (Moscow, RU) Uncoupling effect of lauryl sulfate on mitochondria. Communicated by Erich Gnaiger. |
| 4-08P | Tímea Kurdiová (Bratislava, SK) Measurement of the mitochondrial respiration capacity in permeabilized muscle fibers from cold adapted mice. Communicated by Erich Gnaiger. | |
| 16:30-17:45 | Coffee and Posters | |
| Chair:Dominique Votion (BE), Charles Hoppel (US) | ||
| 4-09L | 17:45-18:45 | Anthony J.R. Hickey (Auckland, NZ) Depressed endogenous mitochondrial respiration stimulates elevated cardiac superoxide production in spontaneously hypertensive rats. |
| 19:00 | Dinner | |
| 21:00 | MiPsociety Party |
5 - Thursday, 17. July
- Mitochondrial molecular physiology - Abstracts Day 5
| Chair: Francesca Scandurra (AT), Guy C Brown (UK) | ||
| 5-01L | 09:00-10:30 | Steven C Hand (Baton Rouge, US) Mitochondria and apoptosis: Energy-limited states and signaling for cell death. |
| 11:00 | Coffee | |
| 5-02L | 11:30-12:45 | Charles Hoppel (Cleveland, US) Integrated mitochondrial function and the clinical utility of polarographic analysis. |
| 13:00 | Lunch | |
| Chair: Charles Hoppel (US), Erich Gnaiger (AT) | ||
| 5-03L | 15:00-16:00 | Steven C Hand (Baton Rouge, US) Mitochondrial targeting of protein import. |
| Flash presentations of posters: | ||
| 5-04P | 16:00-16:15 | Ana Paula P. da Silva (Rio de Janeiro, BR) Differential inhibition of energy-producing pathways of hepg-2 cells by 3-bromopyruvate. Communicated by Steven C Hand. |
| 5-05P | 16:15-16:30 | Elisa Sottotetti (Bologna, IT) PKA stimulation protects transformed cells from apoptosis induced by glucose depletion, by re-activating mitochondrial activity. Communicated by Erich Gnaiger. |
| 5-06P | 16:30-16:45 | Alexandra Latini (Florianopolis, BR) Seleno compounds prevents the brain energy impairment induced by methylmercury poisoning in adult mice. Communicated by Guy C Brown. |
| 5-07P | 16:45-17:00 | Praturi Gopalakrishna (Hyderabad, IN) Periodontitis: Role of oxidative phosphorylation. Communicated by Guy C Brown. |
| 17:00-17:45 | Coffee and Posters | |
| 17:45-18:30 | MiPsummer Feedback | |
| 18:30 | Break | |
| 19:00 | MiPsummer Dinner at Hotel Mohnenfluh | |
| 5-08S | 21:15 | MiPsummer Special Lecture (in the lecture hall)
Guy C Brown (Cambridge, UK) Mitochondria and the future of death. Guy Brown is the author of ‘The Living End. The future of death, aging and immortality’. Macmillan (2007). |
