From Bioblast
Description
The Free ET-capacity, βE, is the ET capacity corrected for LEAK respiration, βE = E-L. βE is the respiratory capacity potentially available for ion transport and phosphorylation of ADP to ATP. Oxygen consumption in the ET-pathway state, therefore, is partitioned into the free ET capacity, βE, and LEAK respiration, LP, compensating for proton leaks, slip and cation cycling: E = βE+LP (see free OXPHOS capacity).
Abbreviation: βE
Reference: Gnaiger 2014 MitoPathways
MitoPedia concepts:
Respiratory state,
Recommended
MitoPedia topics:
EAGLE
Communicated by Gnaiger E 2014-09-21, edited 2015-01-19.
Coupling control states for βE
- Reference state, ZX: ET capacity, E = EΒ΄-ROX
- Background state, YX: LEAK respiration, L = LΒ΄-ROX
- Metabolic control variable, X=ZX-YX: Scope of uncoupler stimulation, Free ET-capacity, βE = E-L
Flux control factor
- Β» Flux control factor, FCF
- Coupling control factor, 1-YX/ZX: E-L coupling control factor, ET-pathway coupling efficiency: jβE = βE/E =(E-L)/E = 1-L/E
Compare
- mt-Preparations Free OXPHOS capacity, βP = P-L
- Intact cells Free ROUTINE activity, βR = R-L