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Difference between revisions of "MitoEAGLE data: fat"

From Bioblast
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[[File:MITOEAGLE Working groups.jpg|right|400px|MITOEAGLE Working Groups]]
[[File:MITOEAGLE Working groups.jpg|right|400px|MITOEAGLE Working Groups]]


= Project application =
= WG3 Project application =
== WG3 Description ==
== Description ==
:::: Mitochondrial function in fat tissue has received increasing attention. Adipose tissue exerts not only important endocrine but also metabolic functions. Several studies have investigated mt-capacities in this context, showing that changes in the expression of body fat and adipocytes can be traced to alterations of mt-functional characteristics (Yin 2014 J Clin Endocrinol Metab). In morbidly obese patients adipocytes from visceral vs subcutaneous fat depots show distinct respiratory control patterns (KraunsĆøe 2010 mJ Physiol), a finding later confirmed in mice. The great potential of respirometric investigations of fat tissue can be further exploited by developing interlaboratory diagnostic standards. The aim of WG2 will be to bring together leading experts studying mitochondrial function in adipose tissue and adipocytes, comparable to the tasks described for WG2.
:::: Mitochondrial function in fat tissue has received increasing attention. Adipose tissue exerts not only important endocrine but also metabolic functions. Several studies have investigated mt-capacities in this context, showing that changes in the expression of body fat and adipocytes can be traced to alterations of mt-functional characteristics (Yin 2014 J Clin Endocrinol Metab). In morbidly obese patients adipocytes from visceral vs subcutaneous fat depots show distinct respiratory control patterns (KraunsĆøe 2010 mJ Physiol), a finding later confirmed in mice. The great potential of respirometric investigations of fat tissue can be further exploited by developing interlaboratory diagnostic standards. The aim of WG2 will be to bring together leading experts studying mitochondrial function in adipose tissue and adipocytes, comparable to the tasks described for WG2.


== WG3 Management ==
== Management ==


=== Tasks ===
=== Tasks ===
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= WG3 Participants and task groups =
= WG3 Action =


== WG3 Participants ==
== Participants ==
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{{#ask:[[MitoPedia topic::EAGLE]] [[In country::+]] [[Has COST WG3::+]]
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== WG3 Task groups ==
== Task groups ==


:: ''TG leaders: suggestions discussed at the [[MitoFit Science Camp 2016 Kuehtai AT]].'' Ā 
:: ''TG leaders: suggestions discussed at the [[MitoFit Science Camp 2016 Kuehtai AT]].'' Ā 
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:: TG participants: [[Watala Cezary]]
:: TG participants: [[Watala Cezary]]


== WG3 Comments and discussion ==
== Comments and discussion ==


::::# ''Based on your previous suggestions, with a great pleasure I will take upĀ  some managements duties, i.e. Short-Term Sicentific MissionsĀ  organizations/coordinatings, and/or so on. I choose WG 4 (blood cellsĀ  and culture cells) eventually also WG 3 (other tissues than fat) butĀ  this will depend on grant funds receving(s) in the near future. ... IĀ  have just read the COST evaluation form and I congratulate you thisĀ  beautiful/great success!!!! This news makes me very happy and I am proudĀ  of becoming a member of this "mitochondrial family.'' - '''[[Labieniec-Watala M| Magdalena Labieniec-Watala]]''' (2016).
::::# ''Based on your previous suggestions, with a great pleasure I will take upĀ  some managements duties, i.e. Short-Term Sicentific MissionsĀ  organizations/coordinatings, and/or so on. I choose WG 4 (blood cellsĀ  and culture cells) eventually also WG 3 (other tissues than fat) butĀ  this will depend on grant funds receving(s) in the near future. ... IĀ  have just read the COST evaluation form and I congratulate you thisĀ  beautiful/great success!!!! This news makes me very happy and I am proudĀ  of becoming a member of this "mitochondrial family.'' - '''[[Labieniec-Watala M| Magdalena Labieniec-Watala]]''' (2016).

Revision as of 15:36, 31 August 2016


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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping


MitoEAGLE data: fat



WG3

MITOEAGLE data repository on fat tissues and other tissues


MITOEAGLE Working Groups

WG3 Project application

Description

Mitochondrial function in fat tissue has received increasing attention. Adipose tissue exerts not only important endocrine but also metabolic functions. Several studies have investigated mt-capacities in this context, showing that changes in the expression of body fat and adipocytes can be traced to alterations of mt-functional characteristics (Yin 2014 J Clin Endocrinol Metab). In morbidly obese patients adipocytes from visceral vs subcutaneous fat depots show distinct respiratory control patterns (KraunsĆøe 2010 mJ Physiol), a finding later confirmed in mice. The great potential of respirometric investigations of fat tissue can be further exploited by developing interlaboratory diagnostic standards. The aim of WG2 will be to bring together leading experts studying mitochondrial function in adipose tissue and adipocytes, comparable to the tasks described for WG2.

Management

Tasks

  1. Kick-off meeting discussing mt fitness evaluated in fat tissue, future applications, consensus protocols and reporting schemes in a standardize format.
  2. Collection and indexing of the data sets as required for statistical analysis.
  3. Draft a comprehensive review on mt-function in adipose tissue (registration at PROSPERO, link with EQUATOR).


Milestones

  1. Kick-off meeting.
  2. Data sets entered in standardized format.
  3. Summary, interpretation and discussion of data for review.


Deliverables

  1. Guidelines for future research and recommendations for the evaluation of respiratory characteristics in fat tissue.
  2. A database on mt fitness evaluated with fat tissue from humans and model organisms and post-study reports (PubMed Commons).
  3. Draft of review manuscript.


WG3 Action

Participants

CountryCityContact
AustriaInnsbruckGnaiger Erich
AustriaSalzburgMayr JA
AustriaInnsbruckJansen-Duerr Pidder
AustriaInnsbruckDoerrier Carolina
AustriaInnsbruckSobotka Ondrej
AustriaInnsbruckBergmeister Lisa
BelgiumLeuvenBird Matthew
BelgiumNamurRenard P
BelgiumNamurStorder Julie
BelgiumNamurArnould Thierry
BrasilBrasiliaDe Bem Andreza Fabro
BrazilSao PauloFestuccia William T
BulgariaStara ZagoraGeorgieva T
CanadaQuebecJoseph Vincent
CroatiaZagrebCurik I
CroatiaSplitLjubkovic M
Czech RepublicHradec KraloveStankova Pavla
Czech RepublicHradec KraloveNozickova Katerina
Czech RepublicHradec KraloveMaseko Tumisang Edward
Czech RepublicHradec KraloveCervinkova Zuzana
Czech RepublicHradec KraloveEndlicher Rene
Czech RepublicHradec KraloveBanni Aml
Czech RepublicHradec KraloveKucera Otto
Czech Republic and AustraliaPrague and SouthportNeuzil Jiri
DenmarkCopenhagenMa Tao
DenmarkCopenhagenKaravaeva Iuliia
DenmarkMalovHey-Mogensen M
FinlandHelsinkiPirinen E
FranceMontpellier Cedex 01Feillet Coudray C
FranceBordeaux cedexMourier A
GermanyUlmSchaefer PM
GermanyColognePesta Dominik
GermanyFreisingKlingenspor Martin
GermanyUlmMerz Tamara
GermanyDuesseldorfRoden Michael
GermanyFrankfurt am MainKoenig M
GermanyFreisingSchoettl T
GermanyFreisingFromme Tobias
GermanyFrankfurt am MainThinnes A
GermanyBiberach an der RiƟNold V
GermanyDuesseldorfJelenik T
GermanyLeipzigOst Mario
GreeceAthensTrougakos Ioannis P
HungaryBudapestTretter Laszlo
HungaryDebrecenVirag L
HungaryDebrecenVerebne Tar K
IsraelHaifaEne H
IsraelRishon Le ZionHachmo Yafit
IsraelHaifaBen-Shachar Dorit
IsraelZrifinSova Marina
ItalyPadovaScorrano L
ItalyPisaGastaldelli Amalia
ItalyAnconaBattino Maurizio
ItalyPadovaZiviani E
ItalyPadovaGiacomello M
ItalyBolognaGenova Maria Luisa
ItalyPadovaMarchesan Elena
ItalyNovaraReano Simone
ItalyAgrigentoDi Nolfo F
ItalyRomeScatena Roberto
LatviaRigaBello Fiona
LithuaniaKaunasArandarcikaite Odeta
LithuaniaKaunasBorutaite Vilma
NetherlandsWageningenKeijer Jaap
NetherlandsWageningenShi W
NorwayOsloEide L
NorwayTromsoeLund T
NorwayTromsoeSchots Pauke C
NorwayTromsoeJansen Kirsten M
NorwayUllevƄlMarstein H
PolandLodzWatala Cezary
PolandLodzLabieniec-Watala Magdalena
PortugalCoimbraCarvalho Cristina
PortugalCoimbraPalmeira Carlos
PortugalCoimbraDias Candida
PortugalCoimbreJones John G
PortugalCoimbraCarvalho Eugenia
PortugalPortoMendes D
PortugalPortoCoxito Pedro
PortugalCoimbraNunes Sara
PortugalPortoBeleza Jorge
PortugalPortoMagalhaes Jose
PortugalCoimbraPereira Susana P
PortugalCoimbraPreguica Ines
Republic of KoreaYuseong-gu DaejeonQuang Don T
Republic of MacedoniaStipRuskovska T
SerbiaBelgradMarkovic Ivanka
SingaporeSingaporeSingh Brijesh Kumar
SlovakiaBratislavaSumbalova Zuzana
SpainValenciaCasado Pinna Marta
SpainBarcelonaSanchez Feutrie M
SpainBarcelonaArago Marc
SpainBellaterra/ BarcelonaQuintana A
SpainDerio, BIGoikoetxea Usandizaga Naroa
SpainBarcelonaClaret M
SpainBarcelonaMoren C
SpainBarcelonaRibeiro ML
SpainDerio, Bizkaia. Basque CountryMartinez-Chantar ML
SpainGranadaQuiles JL
SpainA CoruƱaMayan MD
SpainBarcelonaHerrero L
SpainBarcelonaGarrabou Gloria
SpainMadridMonsalve Maria
SpainBarcelonaDahdah Norma Ramon
SpainBarcelonaSoler Vazquez DC
SpainValenciaFuertes Agudo Marina
SpainMadridPeral B
SpainSevillaMuntane Jordi
SpainMadridMoran M
SpainBarcelonaPerales Jose Carles
SpainSevillaBustos Matilde
SpainBarcelonaVillena Josep A
SpainBarcelonaGama Perez Pau
SpainBarcelonaGarcia-Roves Pablo Miguel
SwedenStockholmGao Yun
SwedenStockholmNedergaard J
SwedenStockholmShabalina Irina G
SwedenStockholmCannon B
SwitzerlandLausanneBurtscher Johannes
SwitzerlandZĆ¼richSchneider Gasser Edith Mariane
TurkeyAnkaraOlgar Yusuf
TurkeyMeram/KonyaCelen Murat C
TurkeyAnkaraTuncay Erkan
TurkeyAnkaraAkcali KC
TurkeyAnkaraTuran Belma
TurkeyAnkaraDegirmenci S
TurkeyAnkaraDurak A
USASt LouisWelch R
USABoca RatonKhamoui Andy V
USANew YorkGalkin Alexander
USACamdenSolesio Maria E
USAFairbanksO'Brien Kristin
USAPhiladelphiaTomar Dhanendra
USALittle RockPorter Craig
USAPhiladelphiaJadiya Pooja
United KingdomLeedsBoyle JP
United KingdomNottinghamChakrabarti Lisa
United KingdomBirminghamJoanisse S
United KingdomBirminghamGarten Antje
United KingdomBrightonMoore Anthony L
United KingdomLoughboroughEbanks Brad

Task groups

TG leaders: suggestions discussed at the MitoFit Science Camp 2016 Kuehtai AT.
TG participants: listed as a summary from the feedback received.

TG3.1 Fat

TG leader: Nedergaard Jan
TG participants: Palmeira Carlos

TG3.2 Liver

TG leaders: Cervinkova Zuzana (suggested) / Sumbalova Zuzana
TG participants: Monsalve Maria, Palmeira Carlos

TG3.3 Neuronal

TG leaders: Sandi Carmen (suggested) / Borutaite Vilma (suggested)
TG participants: Watala Cezary

Comments and discussion

  1. Based on your previous suggestions, with a great pleasure I will take up some managements duties, i.e. Short-Term Sicentific Missions organizations/coordinatings, and/or so on. I choose WG 4 (blood cells and culture cells) eventually also WG 3 (other tissues than fat) but this will depend on grant funds receving(s) in the near future. ... I have just read the COST evaluation form and I congratulate you this beautiful/great success!!!! This news makes me very happy and I am proud of becoming a member of this "mitochondrial family. - Magdalena Labieniec-Watala (2016).
  2. Please, find enclosed my declaration to participate with my team in the following workgroups: WG1, WG2, WG3, WG4. We are now involved and have been in not a distant past ā€“ in studying of the following cell /tissue types:
    1. Blood cells, with particular emphasis on platelets and lymphocytes ā€“ isolated from animals and humans.
    2. Endothelial cells, fibroblasts, neurocytes (neuroblastoma), astrocytes, cancer cell lines ā€“ predominantly cultured.
    3. Hepatocytes, cardiomyocytes, cell isolated from brain ā€“ isolated from lab animals. - Cezary Watala (2016).
  3. I have already contacted the portuguese CNC to nominate me for the MC of theaction. Concerning my active participation, taking into account the type of work we do in my lab I could be included in all WGs. As you know we work with mitochondria from liver, muscle and fat, as well as cultured cells from different origins (WG2-4). The elaboration of SOPs (WG1) we can certainly contribute (see the book I edited on Mitochondrial Bioenergetics and in which you contribute a chapter). I believe that everybody can be part of the WG5, but as the coordinators of the action, you and Sandra should decide what is best for the success of the action. - Carlos Palmeira (2016).


Projects in progress

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