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Difference between revisions of "MitoEAGLE data: fat"

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[[File:MITOEAGLE Working groups.jpg|right|400px|MITOEAGLE Working Groups]]
[[File:MITOEAGLE Working groups.jpg|right|400px|MITOEAGLE Working Groups]]
= Project application =
== WG3 Description ==
== WG3 Description ==
:::: Mitochondrial function in fat tissue has received increasing attention. Adipose tissue exerts not only important endocrine but also metabolic functions. Several studies have investigated mt-capacities in this context, showing that changes in the expression of body fat and adipocytes can be traced to alterations of mt-functional characteristics (Yin 2014 J Clin Endocrinol Metab). In morbidly obese patients adipocytes from visceral vs subcutaneous fat depots show distinct respiratory control patterns (Kraunsøe 2010 mJ Physiol), a finding later confirmed in mice. The great potential of respirometric investigations of fat tissue can be further exploited by developing interlaboratory diagnostic standards. The aim of WG2 will be to bring together leading experts studying mitochondrial function in adipose tissue and adipocytes, comparable to the tasks described for WG2.
:::: Mitochondrial function in fat tissue has received increasing attention. Adipose tissue exerts not only important endocrine but also metabolic functions. Several studies have investigated mt-capacities in this context, showing that changes in the expression of body fat and adipocytes can be traced to alterations of mt-functional characteristics (Yin 2014 J Clin Endocrinol Metab). In morbidly obese patients adipocytes from visceral vs subcutaneous fat depots show distinct respiratory control patterns (Kraunsøe 2010 mJ Physiol), a finding later confirmed in mice. The great potential of respirometric investigations of fat tissue can be further exploited by developing interlaboratory diagnostic standards. The aim of WG2 will be to bring together leading experts studying mitochondrial function in adipose tissue and adipocytes, comparable to the tasks described for WG2.
<br/> <br/> <br/>
== WG3 Participants ==
{{#ask:[[MitoPedia topic::EAGLE]] [[In country::+]] [[Has COST WG3::+]]
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== WG3 Management ==
== WG3 Management ==
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:::# Draft of review manuscript.
:::# Draft of review manuscript.


== WG3 Feedback ==
 
= WG3 Participants and task groups =
 
== WG3 Participants ==
{{#ask:[[MitoPedia topic::EAGLE]] [[In country::+]] [[Has COST WG3::+]]
| mainlabel=-
|?In country=Country
|?In city=City
|?=Contact
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== WG3 Task groups ==
 
=== TG3.1 Fat ===
:: TG leader: [[Nedergaard Jan]]
:: TG participants: [[Palmeira Carlos]]
 
=== TG3.2 Liver ===
:: TG leaders: [[Cervinkova Zuzana]] (suggested) / [[Sumbalova Zuzana]]
:: TG participants: [[Palmeira Carlos]]
 
=== TG3.3 Neuronal ===
:: TG leaders: [[Sandi Carmen]] (suggested) / [[Borutaite Vilma]] (suggested)
:: TG participants: [[Watala Cezary]]
 
== WG3 Comments and discussion ==


::::# ''Based on your previous suggestions, with a great pleasure I will take up  some managements duties, i.e. Short-Term Sicentific Missions  organizations/coordinatings, and/or so on. I choose WG 4 (blood cells  and culture cells) eventually also WG 3 (other tissues than fat) but  this will depend on grant funds receving(s) in the near future. ... I  have just read the COST evaluation form and I congratulate you this  beautiful/great success!!!! This news makes me very happy and I am proud  of becoming a member of this "mitochondrial family.'' - '''[[Labieniec-Watala M| Magdalena Labieniec-Watala]]''' (2016).
::::# ''Based on your previous suggestions, with a great pleasure I will take up  some managements duties, i.e. Short-Term Sicentific Missions  organizations/coordinatings, and/or so on. I choose WG 4 (blood cells  and culture cells) eventually also WG 3 (other tissues than fat) but  this will depend on grant funds receving(s) in the near future. ... I  have just read the COST evaluation form and I congratulate you this  beautiful/great success!!!! This news makes me very happy and I am proud  of becoming a member of this "mitochondrial family.'' - '''[[Labieniec-Watala M| Magdalena Labieniec-Watala]]''' (2016).

Revision as of 14:10, 17 August 2016


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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping


MitoEAGLE data: fat



WG3

MITOEAGLE data repository on fat tissues and other tissues


MITOEAGLE Working Groups

Project application

WG3 Description

Mitochondrial function in fat tissue has received increasing attention. Adipose tissue exerts not only important endocrine but also metabolic functions. Several studies have investigated mt-capacities in this context, showing that changes in the expression of body fat and adipocytes can be traced to alterations of mt-functional characteristics (Yin 2014 J Clin Endocrinol Metab). In morbidly obese patients adipocytes from visceral vs subcutaneous fat depots show distinct respiratory control patterns (Kraunsøe 2010 mJ Physiol), a finding later confirmed in mice. The great potential of respirometric investigations of fat tissue can be further exploited by developing interlaboratory diagnostic standards. The aim of WG2 will be to bring together leading experts studying mitochondrial function in adipose tissue and adipocytes, comparable to the tasks described for WG2.

WG3 Management

Tasks

  1. Kick-off meeting discussing mt fitness evaluated in fat tissue, future applications, consensus protocols and reporting schemes in a standardize format.
  2. Collection and indexing of the data sets as required for statistical analysis.
  3. Draft a comprehensive review on mt-function in adipose tissue (registration at PROSPERO, link with EQUATOR).


Milestones

  1. Kick-off meeting.
  2. Data sets entered in standardized format.
  3. Summary, interpretation and discussion of data for review.


Deliverables

  1. Guidelines for future research and recommendations for the evaluation of respiratory characteristics in fat tissue.
  2. A database on mt fitness evaluated with fat tissue from humans and model organisms and post-study reports (PubMed Commons).
  3. Draft of review manuscript.


WG3 Participants and task groups

WG3 Participants

CountryCityContact
AustriaInnsbruckDoerrier Carolina
AustriaInnsbruckSobotka Ondrej
AustriaInnsbruckBergmeister Lisa
AustriaInnsbruckGnaiger Erich
AustriaInnsbruckJansen-Duerr Pidder
AustriaSalzburgMayr JA
BelgiumNamurStorder Julie
BelgiumNamurArnould Thierry
BelgiumLeuvenBird Matthew
BelgiumNamurRenard P
BrasilBrasiliaDe Bem Andreza Fabro
BrazilSao PauloFestuccia William T
BulgariaStara ZagoraGeorgieva T
CanadaQuebecJoseph Vincent
CroatiaSplitLjubkovic M
CroatiaZagrebCurik I
Czech RepublicHradec KraloveBanni Aml
Czech RepublicHradec KraloveKucera Otto
Czech RepublicHradec KraloveStankova Pavla
Czech RepublicHradec KraloveNozickova Katerina
Czech RepublicHradec KraloveMaseko Tumisang Edward
Czech RepublicHradec KraloveCervinkova Zuzana
Czech RepublicHradec KraloveEndlicher Rene
Czech Republic and AustraliaPrague and SouthportNeuzil Jiri
DenmarkCopenhagenKaravaeva Iuliia
DenmarkMalovHey-Mogensen M
DenmarkCopenhagenMa Tao
FinlandHelsinkiPirinen E
FranceMontpellier Cedex 01Feillet Coudray C
FranceBordeaux cedexMourier A
GermanyDuesseldorfJelenik T
GermanyLeipzigOst Mario
GermanyUlmSchaefer PM
GermanyColognePesta Dominik
GermanyFreisingKlingenspor Martin
GermanyUlmMerz Tamara
GermanyDuesseldorfRoden Michael
GermanyFrankfurt am MainKoenig M
GermanyFreisingSchoettl T
GermanyFreisingFromme Tobias
GermanyFrankfurt am MainThinnes A
GermanyBiberach an der RißNold V
GreeceAthensTrougakos Ioannis P
HungaryDebrecenVirag L
HungaryDebrecenVerebne Tar K
HungaryBudapestTretter Laszlo
IsraelHaifaBen-Shachar Dorit
IsraelZrifinSova Marina
IsraelHaifaEne H
IsraelRishon Le ZionHachmo Yafit
ItalyPadovaGiacomello M
ItalyBolognaGenova Maria Luisa
ItalyPadovaMarchesan Elena
ItalyNovaraReano Simone
ItalyAgrigentoDi Nolfo F
ItalyRomeScatena Roberto
ItalyPadovaScorrano L
ItalyPisaGastaldelli Amalia
ItalyAnconaBattino Maurizio
ItalyPadovaZiviani E
LatviaRigaBello Fiona
LithuaniaKaunasArandarcikaite Odeta
LithuaniaKaunasBorutaite Vilma
NetherlandsWageningenShi W
NetherlandsWageningenKeijer Jaap
NorwayUllevålMarstein H
NorwayTromsoeLund T
NorwayOsloEide L
NorwayTromsoeSchots Pauke C
NorwayTromsoeJansen Kirsten M
PolandLodzWatala Cezary
PolandLodzLabieniec-Watala Magdalena
PortugalPortoBeleza Jorge
PortugalPortoMagalhaes Jose
PortugalCoimbraNunes Sara
PortugalCoimbraPereira Susana P
PortugalCoimbraPreguica Ines
PortugalCoimbraCarvalho Cristina
PortugalCoimbraPalmeira Carlos
PortugalCoimbraDias Candida
PortugalCoimbraCarvalho Eugenia
PortugalPortoMendes D
PortugalCoimbreJones John G
PortugalPortoCoxito Pedro
Republic of KoreaYuseong-gu DaejeonQuang Don T
Republic of MacedoniaStipRuskovska T
SerbiaBelgradMarkovic Ivanka
SingaporeSingaporeSingh Brijesh Kumar
SlovakiaBratislavaSumbalova Zuzana
SpainBarcelonaGarrabou Gloria
SpainMadridMonsalve Maria
SpainBarcelonaSoler Vazquez DC
SpainValenciaFuertes Agudo Marina
SpainBarcelonaDahdah Norma Ramon
SpainMadridPeral B
SpainSevillaMuntane Jordi
SpainMadridMoran M
SpainBarcelonaPerales Jose Carles
SpainSevillaBustos Matilde
SpainBarcelonaVillena Josep A
SpainBarcelonaGama Perez Pau
SpainValenciaCasado Pinna Marta
SpainBarcelonaGarcia-Roves Pablo Miguel
SpainBarcelonaSanchez Feutrie M
SpainBarcelonaArago Marc
SpainBellaterra/ BarcelonaQuintana A
SpainBarcelonaClaret M
SpainDerio, BIGoikoetxea Usandizaga Naroa
SpainBarcelonaMoren C
SpainBarcelonaRibeiro ML
SpainDerio, Bizkaia. Basque CountryMartinez-Chantar ML
SpainGranadaQuiles JL
SpainA CoruñaMayan MD
SpainBarcelonaHerrero L
SwedenStockholmShabalina Irina G
SwedenStockholmCannon B
SwedenStockholmGao Yun
SwedenStockholmNedergaard J
SwitzerlandLausanneBurtscher Johannes
SwitzerlandZürichSchneider Gasser Edith Mariane
TurkeyAnkaraAkcali KC
TurkeyAnkaraTuran Belma
TurkeyAnkaraDegirmenci S
TurkeyAnkaraDurak A
TurkeyAnkaraOlgar Yusuf
TurkeyMeram/KonyaCelen Murat C
TurkeyAnkaraTuncay Erkan
USAWinston-SalemTomar Dhanendra
USALittle RockPorter Craig
USAPhiladelphiaJadiya Pooja
USASt LouisWelch R
USABoca RatonKhamoui Andy V
USANew YorkGalkin Alexander
USACamdenSolesio Maria E
USAFairbanksO'Brien Kristin
United KingdomBirminghamJoanisse S
United KingdomBirminghamGarten Antje
United KingdomBrightonMoore Anthony L
United KingdomLoughboroughEbanks Brad
United KingdomLeedsBoyle JP
United KingdomNottinghamChakrabarti Lisa

WG3 Task groups

TG3.1 Fat

TG leader: Nedergaard Jan
TG participants: Palmeira Carlos

TG3.2 Liver

TG leaders: Cervinkova Zuzana (suggested) / Sumbalova Zuzana
TG participants: Palmeira Carlos

TG3.3 Neuronal

TG leaders: Sandi Carmen (suggested) / Borutaite Vilma (suggested)
TG participants: Watala Cezary

WG3 Comments and discussion

  1. Based on your previous suggestions, with a great pleasure I will take up some managements duties, i.e. Short-Term Sicentific Missions organizations/coordinatings, and/or so on. I choose WG 4 (blood cells and culture cells) eventually also WG 3 (other tissues than fat) but this will depend on grant funds receving(s) in the near future. ... I have just read the COST evaluation form and I congratulate you this beautiful/great success!!!! This news makes me very happy and I am proud of becoming a member of this "mitochondrial family. - Magdalena Labieniec-Watala (2016).
  2. Please, find enclosed my declaration to participate with my team in the following workgroups: WG1, WG2, WG3, WG4. We are now involved and have been in not a distant past – in studying of the following cell /tissue types:
    1. Blood cells, with particular emphasis on platelets and lymphocytes – isolated from animals and humans.
    2. Endothelial cells, fibroblasts, neurocytes (neuroblastoma), astrocytes, cancer cell lines – predominantly cultured.
    3. Hepatocytes, cardiomyocytes, cell isolated from brain – isolated from lab animals. - Cezary Watala (2016).
  3. I have already contacted the portuguese CNC to nominate me for the MC of theaction. Concerning my active participation, taking into account the type of work we do in my lab I could be included in all WGs. As you know we work with mitochondria from liver, muscle and fat, as well as cultured cells from different origins (WG2-4). The elaboration of SOPs (WG1) we can certainly contribute (see the book I edited on Mitochondrial Bioenergetics and in which you contribute a chapter). I believe that everybody can be part of the WG5, but as the coordinators of the action, you and Sandra should decide what is best for the success of the action. - Carlos Palmeira (2016).


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