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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping
MitoEAGLE data: fat
WG3
- MITOEAGLE data repository on fat tissues and other tissues
WG3 Description
- Mitochondrial function in fat tissue has received increasing attention. Adipose tissue exerts not only important endocrine but also metabolic functions. Several studies have investigated mt-capacities in this context, showing that changes in the expression of body fat and adipocytes can be traced to alterations of mt-functional characteristics (Yin 2014 J Clin Endocrinol Metab). In morbidly obese patients adipocytes from visceral vs subcutaneous fat depots show distinct respiratory control patterns (Kraunsøe 2010 mJ Physiol), a finding later confirmed in mice. The great potential of respirometric investigations of fat tissue can be further exploited by developing interlaboratory diagnostic standards. The aim of WG2 will be to bring together leading experts studying mitochondrial function in adipose tissue and adipocytes, comparable to the tasks described for WG2.
WG3 Participants
Country City Contact Austria Innsbruck Jansen-Duerr Pidder Austria Salzburg Mayr JA Austria Innsbruck Doerrier Carolina Austria Innsbruck Sobotka Ondrej Austria Innsbruck Bergmeister Lisa Austria Innsbruck Gnaiger Erich Belgium Leuven Bird Matthew Belgium Namur Storder Julie Belgium Namur Arnould Thierry Belgium Namur Renard P Brasil Brasilia De Bem Andreza Fabro Brazil Sao Paulo Festuccia William T Bulgaria Stara Zagora Georgieva T Canada Quebec Joseph Vincent Croatia Split Ljubkovic M Croatia Zagreb Curik I Czech Republic Hradec Kralove Endlicher Rene Czech Republic Hradec Kralove Banni Aml Czech Republic Hradec Kralove Kucera Otto Czech Republic Hradec Kralove Stankova Pavla Czech Republic Hradec Kralove Nozickova Katerina Czech Republic Hradec Kralove Maseko Tumisang Edward Czech Republic Hradec Kralove Cervinkova Zuzana Czech Republic and Australia Prague and Southport Neuzil Jiri Denmark Copenhagen Karavaeva Iuliia Denmark Malov Hey-Mogensen M Denmark Copenhagen Ma Tao Finland Helsinki Pirinen E France Montpellier Cedex 01 Feillet Coudray C France Bordeaux cedex Mourier A Germany Freising Schoettl T Germany Frankfurt am Main Thinnes A Germany Biberach an der Riß Nold V Germany Duesseldorf Jelenik T Germany Freising Fromme Tobias Germany Leipzig Ost Mario Germany Ulm Schaefer PM Germany Cologne Pesta Dominik Germany Freising Klingenspor Martin Germany Ulm Merz Tamara Germany Duesseldorf Roden Michael Germany Frankfurt am Main Koenig M Greece Athens Trougakos Ioannis P Hungary Budapest Tretter Laszlo Hungary Debrecen Verebne Tar K Hungary Debrecen Virag L Israel Haifa Ben-Shachar Dorit Israel Zrifin Sova Marina Israel Haifa Ene H Israel Rishon Le Zion Hachmo Yafit Italy Padova Ziviani E Italy Padova Giacomello M Italy Bologna Genova Maria Luisa Italy Padova Marchesan Elena Italy Novara Reano Simone Italy Rome Scatena Roberto Italy Agrigento Di Nolfo F Italy Padova Scorrano L Italy Pisa Gastaldelli Amalia Italy Ancona Battino Maurizio Latvia Riga Bello Fiona Lithuania Kaunas Arandarcikaite Odeta Lithuania Kaunas Borutaite Vilma Netherlands Wageningen Keijer Jaap Netherlands Wageningen Shi W Norway Tromsoe Jansen Kirsten M Norway Ullevål Marstein H Norway Tromsoe Schots Pauke C Norway Oslo Eide L Norway Tromsoe Lund T Poland Lodz Watala Cezary Poland Lodz Labieniec-Watala Magdalena Portugal Coimbra Carvalho Eugenia Portugal Porto Mendes D Portugal Porto Beleza Jorge Portugal Coimbra Preguica Ines Portugal Porto Magalhaes Jose Portugal Coimbra Pereira Susana P Portugal Coimbra Carvalho Cristina Portugal Coimbre Jones John G Portugal Porto Coxito Pedro Portugal Coimbra Nunes Sara Portugal Coimbra Palmeira Carlos Portugal Coimbra Dias Candida Republic of Korea Yuseong-gu Daejeon Quang Don T Republic of Macedonia Stip Ruskovska T Serbia Belgrad Markovic Ivanka Singapore Singapore Singh Brijesh Kumar Slovakia Bratislava Sumbalova Zuzana Spain Barcelona Perales Jose Carles Spain Derio, Bizkaia. Basque Country Martinez-Chantar ML Spain Granada Quiles JL Spain Sevilla Bustos Matilde Spain Barcelona Moren C Spain Barcelona Ribeiro ML Spain A Coruña Mayan MD Spain Barcelona Herrero L Spain Barcelona Villena Josep A Spain Madrid Monsalve Maria Spain Barcelona Garrabou Gloria Spain Barcelona Garcia-Roves Pablo Miguel Spain Barcelona Soler Vazquez DC Spain Valencia Fuertes Agudo Marina Spain Madrid Peral B Spain Sevilla Muntane Jordi Spain Madrid Moran M Spain Derio, BI Goikoetxea Usandizaga Naroa Spain Barcelona Gama Perez Pau Spain Barcelona Sanchez Feutrie M Spain Valencia Casado Pinna Marta Spain Barcelona Arago Marc Spain Bellaterra/ Barcelona Quintana A Spain Barcelona Dahdah Norma Ramon Spain Barcelona Claret M Sweden Stockholm Shabalina Irina G Sweden Stockholm Cannon B Sweden Stockholm Gao Yun Sweden Stockholm Nedergaard J Switzerland Lausanne Burtscher Johannes Switzerland Zürich Schneider Gasser Edith Mariane Turkey Ankara Tuncay Erkan Turkey Ankara Akcali KC Turkey Ankara Turan Belma Turkey Ankara Degirmenci S Turkey Ankara Durak A Turkey Ankara Olgar Yusuf Turkey Meram/Konya Celen Murat C USA Fairbanks O'Brien Kristin USA Little Rock Porter Craig USA Philadelphia Jadiya Pooja USA St Louis Welch R USA Camden Solesio Maria E USA Winston-Salem Tomar Dhanendra USA Boca Raton Khamoui Andy V USA New York Galkin Alexander United Kingdom Nottingham Chakrabarti Lisa United Kingdom Loughborough Ebanks Brad United Kingdom Birmingham Joanisse S United Kingdom Birmingham Garten Antje United Kingdom Brighton Moore Anthony L United Kingdom Leeds Boyle JP WG3 Management
Tasks
- Kick-off meeting discussing mt fitness evaluated in fat tissue, future applications, consensus protocols and reporting schemes in a standardize format.
- Collection and indexing of the data sets as required for statistical analysis.
- Draft a comprehensive review on mt-function in adipose tissue (registration at PROSPERO, link with EQUATOR).
Milestones
- Kick-off meeting.
- Data sets entered in standardized format.
- Summary, interpretation and discussion of data for review.
Deliverables
- Guidelines for future research and recommendations for the evaluation of respiratory characteristics in fat tissue.
- A database on mt fitness evaluated with fat tissue from humans and model organisms and post-study reports (PubMed Commons).
- Draft of review manuscript.
Projects in progress
- » MiPMap
Next steps