Difference between revisions of "PBMC"
From Bioblast
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{{MitoPedia | {{MitoPedia | ||
|abbr=PBMC | |abbr=PBMC | ||
|description='''Peripheral blood mononuclear | |description='''Peripheral blood mononuclear cells''' (PBMC) are a fraction of the leucocyte population in the blood composed by cells with round nucleus. PBMC consist of lymphocytes (T, B and NK cells) and monocytes. During extraction, neutrophils and platelets (PLT) can be found in the PBMC fraction, where PLT are considered as a contamination. | ||
|info=[[MiPNet21.17 BloodCellsIsolation]] | |info=[[MiPNet21.17 BloodCellsIsolation]] | ||
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== Cell size == | == Cell size == | ||
::::* Lymphocytes: 210 | ::::* Lymphocytes: 210 fL volume; 7 to 10 µm diameter [1] | ||
::::* Monocytes: 180 | ::::* Monocytes: 180 fL volume; 15 to 25 µm diameter [2] | ||
Latest revision as of 15:16, 21 February 2024
- high-resolution terminology - matching measurements at high-resolution
PBMC
Description
Peripheral blood mononuclear cells (PBMC) are a fraction of the leucocyte population in the blood composed by cells with round nucleus. PBMC consist of lymphocytes (T, B and NK cells) and monocytes. During extraction, neutrophils and platelets (PLT) can be found in the PBMC fraction, where PLT are considered as a contamination.
Abbreviation: PBMC
Reference: MiPNet21.17 BloodCellsIsolation
Cell size
- Lymphocytes: 210 fL volume; 7 to 10 µm diameter [1]
- Monocytes: 180 fL volume; 15 to 25 µm diameter [2]
References
- Segel GB, Cokelet GR, Lichtman MA (1981) The measurement of lymphocyte volume: importance of reference particle deformability and counting solution tonicity. Blood 57:894-9
- Mardi D, Fwity B, Lobmann R, Ambrosch A (2010) Mean cell volume of neutrophils and monocytes compared with C-reactive protein, interleukin-6 and white blood cell count for prediction of sepsis and nonsystemic bacterial infections. Int J Lab Hematol 32:410-8
