PMS-pathway control state

high-resolution terminology - matching measurements at high-resolution

PMS-pathway control state

Description

PMS: Pyruvate & Malate & Succinate.

MitoPathway control: CI&II

Transaminase catalyzes the reaction from oxaloacetate to 2-oxoglutarate, which then establishes a cycle without generation of citrate. OXPHOS is higher with GS (CI&II) compared to GM (CI) or SRot (CII). This documents an additive effect of convergent CI&II electron flow to the Q-junction, with consistent results obtained with permeabilized muscle fibres and isolated mitochondria (Gnaiger 2009).

Abbreviation: PMS

Reference: Gnaiger 2014 MitoPathways - Chapter 5.5

MitoPedia O2k and high-resolution respirometry: "SUIT state" is not in the list (O2k hardware, DatLab, Oroboros QM, O2k-Open Support, O2k-Respirometry, O2k-FluoRespirometry) of allowed values for the "MitoPedia O2k and high-resolution respirometry" property. SUIT state"SUIT state" is not in the list (O2k hardware, DatLab, Oroboros QM, O2k-Open Support, O2k-Respirometry, O2k-FluoRespirometry) of allowed values for the "MitoPedia O2k and high-resolution respirometry" property. 

More details

» Additive effect of convergent electron flow

» Respiratory complexes - more than five

» OctPGMSGp pathway control state

» Convergent electron flow

» NS-pathway control state

PMS_L

PMS pathway in the LEAK state can be evaluated in the following SUIT protocols:

PMS_P

PMS pathway in the OXPHOS state can be evaluated in the following SUIT protocols:

PMS_E

PMS pathway in the ET state can be evaluated in the following SUIT protocols:

• SUIT-004

• DL-Protocol for permeabilized fibers (pfi): SUIT-004 O2 pfi D010