Description
The ROUTINE control ratio (R/E coupling control ratio) is the ratio of (partially coupled) ROUTINE respiration and (noncoupled) ET capacity. The R/E control ratio is an expression of how close ROUTINE respiration operates to ET capacity.
Abbreviation: R/E
Reference: Gnaiger 2014 MitoPathways
MitoPedia concepts:
Respiratory control ratio
Boundaries of the ROUTINE control ratio
- R/E increases due to (i) high ATP demand and ADP-stimulated ROUTINE respiration, (ii) partial uncoupling, and (iii) limitation of oxidative capacity by defects of substrate oxidation and complexes of the ET-pathway. The corresponding inverse ratio is the uncoupling control ratio, UCR, which can be seen as an index of apparent ET-pathway excess capacity. The lower boundary of R/E is the L/E flux control ratio, whereas the upper boundary is set by the P/E flux control ratio (OXPHOS/ET capacity).
Biochemical coupling efficiency: from 0 to <1
- More details: Β»Biochemical coupling efficiency
- Compare:
- Excess E-R capacity factor, jExR = (E-R)/E = 1-R/E
- ROUTINE coupling efficiency, jβR = βR/R = (R-L)/R = 1-L/R
- NetROUTINE control ratio, βR/E = (R-L)/E