Rasmussen 2003 Eur J Physiol: Difference between revisions
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{{Labeling | {{Labeling | ||
|injuries=z edited, Aging; Senescence | |injuries=z edited, Aging; Senescence | ||
|organism= | |organism=Human | ||
|tissues= | |tissues=Skeletal muscle | ||
|preparations= | |preparations=Isolated Mitochondria | ||
|enzymes=Complex I, Complex II; Succinate Dehydrogenase, Complex V; ATP Synthase | |enzymes=Complex I, Complex II; Succinate Dehydrogenase, Complex V; ATP Synthase | ||
|topics=Respiration; OXPHOS; ETS Capacity, Flux Control; Additivity; Threshold; Excess Capacity, Substrate; Glucose; TCA Cycle | |topics=Respiration; OXPHOS; ETS Capacity, Flux Control; Additivity; Threshold; Excess Capacity, Substrate; Glucose; TCA Cycle |
Revision as of 07:37, 5 April 2012
Rasmussen UF, Krustrup P, Kjaer M, Rasmussen HN (2003) Human skeletal muscle mitochondrial metabolism in youth and senescence: no signs of functional changes in ATP formation and mitochondrial oxidative capacity. Pflugers Arch β Eur J Physiol 446: 270-278. |
Rasmussen UF, Krustrup P, Kjaer M, Rasmussen HN (2003) Eur J Physiol
Abstract:
Labels:
Stress:z edited"z edited" is not in the list (Cell death, Cryopreservation, Ischemia-reperfusion, Permeability transition, Oxidative stress;RONS, Temperature, Hypoxia, Mitochondrial disease) of allowed values for the "Stress" property., Aging; Senescence"Aging; Senescence" is not in the list (Cell death, Cryopreservation, Ischemia-reperfusion, Permeability transition, Oxidative stress;RONS, Temperature, Hypoxia, Mitochondrial disease) of allowed values for the "Stress" property. Organism: Human Tissue;cell: Skeletal muscle Preparation: Isolated Mitochondria"Isolated Mitochondria" is not in the list (Intact organism, Intact organ, Permeabilized cells, Permeabilized tissue, Homogenate, Isolated mitochondria, SMP, Chloroplasts, Enzyme, Oxidase;biochemical oxidation, ...) of allowed values for the "Preparation" property. Enzyme: Complex I, Complex II; Succinate Dehydrogenase"Complex II; Succinate Dehydrogenase" is not in the list (Adenine nucleotide translocase, Complex I, Complex II;succinate dehydrogenase, Complex III, Complex IV;cytochrome c oxidase, Complex V;ATP synthase, Inner mt-membrane transporter, Marker enzyme, Supercomplex, TCA cycle and matrix dehydrogenases, ...) of allowed values for the "Enzyme" property., Complex V; ATP Synthase"Complex V; ATP Synthase" is not in the list (Adenine nucleotide translocase, Complex I, Complex II;succinate dehydrogenase, Complex III, Complex IV;cytochrome c oxidase, Complex V;ATP synthase, Inner mt-membrane transporter, Marker enzyme, Supercomplex, TCA cycle and matrix dehydrogenases, ...) of allowed values for the "Enzyme" property. Regulation: Respiration; OXPHOS; ETS Capacity"Respiration; OXPHOS; ETS Capacity" is not in the list (Aerobic glycolysis, ADP, ATP, ATP production, AMP, Calcium, Coupling efficiency;uncoupling, Cyt c, Flux control, Inhibitor, ...) of allowed values for the "Respiration and regulation" property., Flux Control; Additivity; Threshold; Excess Capacity"Flux Control; Additivity; Threshold; Excess Capacity" is not in the list (Aerobic glycolysis, ADP, ATP, ATP production, AMP, Calcium, Coupling efficiency;uncoupling, Cyt c, Flux control, Inhibitor, ...) of allowed values for the "Respiration and regulation" property., Substrate; Glucose; TCA Cycle"Substrate; Glucose; TCA Cycle" is not in the list (Aerobic glycolysis, ADP, ATP, ATP production, AMP, Calcium, Coupling efficiency;uncoupling, Cyt c, Flux control, Inhibitor, ...) of allowed values for the "Respiration and regulation" property.
References
Both muscle strength and peak contraction velocity decline, in some muscles even from the age of 20
- [8, 15, 16 17, 22, 23, 26, 27, 28, 29, 30, 32, 36, 37]
The response to training is independent of age
- [8, 9, 15, 17, 22, 23, 30, 32, 36, 37].
Loss of type-II fibres is greater than that of type-I
- [15, 16, 22, 23, 26, 27, 28, 37].
Cytochrome oxidase deficient fibres appear later in increasing, but very small numbers
- [8, 9, 10, 33, 35, 44, 52].
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