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Difference between revisions of "Substrates as electron donors"

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{{MitoPedia
{{MitoPedia
|description=Mitochondrial respiration depends on a continuous flow of electron-supplying [[Substrates|substrates]] across the mitochondrial membranes into the matrix space. Many substrates are strong anions that cannot permeate lipid membranes and hence require carriers.
|abbr=''S''<sub>red</sub>
|type=Respiration
|description='''[[Substrate]]s as electron donors''' are reduced fuel compounds ''S''<sub>red</sub> that are oxidized to an oxidized product ''P''<sub>ox</sub> during H<sup>+</sup>-linked electron transfer, ''S''<sub>red</sub> β†’ ''P''<sub>ox</sub> + 2{H<sup>+</sup> + e<sup>-</sup>}. Mitochondrial respiration depends on a continuous flow of electron-supplying substrates across the mitochondrial membranes into the matrix space. Many substrates are strong anions that cannot permeate lipid membranes and hence require carriers.
|info=Gnaiger E (2023) Complex II ambiguities ― FADH2 in the electron transfer system. MitoFit Preprints 2023.3.v3. https://doi.org/10.26124/mitofit:2023-0003.v3
}}
}}
{{MitoPedia methods
{{Template:Keywords: Substrates and cofactors}}
|mitopedia method=Respirometry
{{MitoPedia topics
|type=Respiration
|mitopedia topic=Substrate and metabolite
}}
{{MitoPedia topics|type=Respiration
}}
{{Labeling
|discipline=Mitochondrial Physiology
|topics=Respiration; OXPHOS; ETS Capacity
}}
}}

Latest revision as of 19:00, 7 May 2023


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Substrates as electron donors

Description

Substrates as electron donors are reduced fuel compounds Sred that are oxidized to an oxidized product Pox during H+-linked electron transfer, Sred β†’ Pox + 2{H+ + e-}. Mitochondrial respiration depends on a continuous flow of electron-supplying substrates across the mitochondrial membranes into the matrix space. Many substrates are strong anions that cannot permeate lipid membranes and hence require carriers.

Abbreviation: Sred

Reference: Gnaiger E (2023) Complex II ambiguities ― FADH2 in the electron transfer system. MitoFit Preprints 2023.3.v3. https://doi.org/10.26124/mitofit:2023-0003.v3


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Substrate
Β» Substrate
Β» Product
Β» Substrates as electron donors
Β» Cellular substrates
Β» MitoPedia: Substrates and metabolites
Β» Substrate-uncoupler-inhibitor titration
Cofactor
Β» Cofactor
Β» Coenzyme, cosubstrate
Β» Nicotinamide adenine dinucleotide
Β» Coenzyme Q2
Β» Prosthetic group
Β» Flavin adenine dinucleotide
Referennces
Β» Gnaiger E (2023) Complex II ambiguities ― FADH2 in the electron transfer system. MitoFit Preprints 2023.3.v6. https://doi.org/10.26124/mitofit:2023-0003.v6


MitoPedia topics: Substrate and metabolite