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Template:Correction FADH2 and S-pathway

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Revision as of 13:15, 19 March 2023 by Gnaiger Erich (talk | contribs) (Created page with "== Correction: FADH<sub>2</sub> and S-pathway == :::Β» Complex II ambiguities :::: A commonly found error on FADH<sub>2</sub> in the S-pathway requires correction. For cl...")
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Correction: FADH2 and S-pathway

Β» Complex II ambiguities
A commonly found error on FADH2 in the S-pathway requires correction. For clarification, see page 48 in Gnaiger (2020)
  • Quote (p 48): "The substrate of CII is succinate, which is oxidized forming fumarate while reducing flavin adenine dinucleotide FAD to FADH2, with further electron transfer to the quinone pool. Whereas reduced NADH is a substrate of Complex I linked to dehydrogenases of the TCA cycle and mt-matrix upstream of CI, reduced FADH2 is a product of Complex II with downstream electron flow from CII to Q."
Gnaiger E (2020) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 5th ed. Bioenerg Commun 2020.2. https://doi.org/10.26124/bec:2020-0002