Difference between revisions of "Template:Current week ecosystem agenda"

Revision as of 08:15, 14 September 2020

2020 Week 38

Sep-14 Mo

World Mitochondrial Disease Week – Sep 13-19

World Mitochondrial Disease Week raises awareness of mitochondrial disease through educational, fundraising and advocacy activities.

See what is happening near you - »https://mitochondrialdiseaseweek.org/events/

Sep-15 Tu - World Lymphoma Awareness Day

OXPHOS as a potential therapeutic target in classical Hodgkin lymphoma

from the O2k-Network »DE Frankfurt Droese S«, »DE Frankfurt Wittig I« and »NL Nijmegen Brandt U«

Birkenmeier K, Droese S, Wittig I, Winkelmann R, Käfer V, Doering C, Hartmann S, Wenz T, Reichert AS, Brandt U, Hansmann ML (2016) Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma are highly dependent on oxidative phosphorylation. Int J Cancer 138:2231-46. »Bioblast link«

Sep-16 We

Why are permeabilized muscle fibers (pfi) a poor sample type for studying reactive oxygen species (ROS) production?

In experiments with pfi, high oxygen concentrations are needed to avoid oxygen limitation. However, the high oxygen pressures used may artificially increase ROS, including H₂O₂ production, making pfi a less optimal model for ROS production studies.
- »Oxygen dependence of ROS production in pfi«
- communicated by »Komlodi Timea« and »Cardoso Luiza«

Sep-17 Th

Did you know that you can measure the respiratory activity available for phosphorylation of ADP to ATP in living cells?

SUIT protocols from the SUIT-003 family will guide you through the titrations needed to analyze free ROUTINE activity.
- »SUIT-003 O2 ce D009« and »SUIT-003 O2 ce-pce D020«
- communicated by »Cardoso Luiza« and »Komlodi Timea«

Sep-18 Fr

Sep-19 Sa

Sep-20 So

ESCI 2020 Virtual Event Sep 20-30

@@ Line 1: / Line 1: @@
-Week 37
+Week 38
-* '''Sep-07 Mo'''
+* '''Sep-14 Mo'''
 :{|
-| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]] [[File:Yellow-take care.png|25px|Take care]]
+| width="100" align="center" | [[Image:MitoGlobal.jpg|45px|link=https://www.mitoglobal.org/index.php/MitoGlobal_Events|MitoGlobal Events]]
-| '''Why it is necessary to perform multiple H<sub>2</sub>O<sub>2</sub> calibrations when using the [[Amplex UltraRed]] (AmR) assay?'''<br>
+| '''World Mitochondrial Disease Week''' – Sep 13-19
-The sensitivity to H<sub>2</sub>O<sub>2</sub> of the Amplex UltraRed assay changes during the experiment, thus requires multiple calibrations. These sensitivity changes may be the function of: 1) experimental time, 2) changes in the optical properties of the respiration medium due to sample/chemical titration, 3) the radical scavenging capacity of the sample, and 4) the concentration of accumulating resorufin (UltroxRed in the case of Amplex UltraRed). Therefore, it is recommended to perform H<sub>2</sub>O<sub>2</sub> calibration before sample addition, after sample addition and multiple times during the experiment.  <br>
+World Mitochondrial Disease Week raises awareness of mitochondrial disease through educational, fundraising and advocacy activities.
-- »[[Komlodi 2018 Methods Mol Biol]]« <br>
-The DLPs for AmR [[SUIT]] protocols already come with multiple steps of H<sub>2</sub>O<sub>2</sub> calibrations implemented. <br>
+See what is happening near you - »[https://mitochondrialdiseaseweek.org/events/ https://mitochondrialdiseaseweek.org/events/]
-- » [https://www.bioblast.at/index.php/SUITbrowser SUITbrowser]« <br>
-- communicated by »[[Komlodi Timea]]« and »[[Cardoso Luiza]]«
 |}
 ----
-* '''Sep-08 Tu'''
+* '''Sep-15 Tu''' - World Lymphoma Awareness Day
 :{|
 | width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]
-|'''Alternative oxidase (AOX) can prevent acute hypoxic pulmonary vasoconstriction in mouse lung'''<br>
+|'''OXPHOS as a potential therapeutic target in classical Hodgkin lymphoma'''<br>
-:from the O2k-Network »[[DE Giessen Weissmann N]]«, »[[ FI Tampere Dufour E]]«, »[[FI Helsinki Jacobs HT]]« and »[[DE Jena Szibor M]]«
+:from the O2k-Network »[[DE Frankfurt Droese S]]«, »[[DE Frankfurt Wittig I]]« and »[[NL Nijmegen Brandt U]]«
-*Sommer N, Alebrahimdehkordi N, Pak O, Knoepp F, Strielkov I, Scheibe S, Dufour E, Andjelekovic A, Sydykov A, Saraji A, Petrovic A, Quanz K, Hecker M, Kumar M, Wahl J, Kraut S, Seeger W, Schermuly RT, Ghofrani HA, Ramser K, Braun T, Jacobs HT, Weissmann N, Szibor M (2020) Bypassing mitochondrial complex III using alternative oxidase inhibits acute pulmonary oxygen sensing. Sci Adv 6:eaba0694. [[Sommer 2020 Sci Adv|»Bioblast link«]]
+*Birkenmeier K, Droese S, Wittig I, Winkelmann R, Käfer V, Doering C, Hartmann S, Wenz T, Reichert AS, Brandt U, Hansmann ML (2016) Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma are highly dependent on oxidative phosphorylation. Int J Cancer 138:2231-46. [[Birkenmeier 2016 Int J Cancer|»Bioblast link«]]
 |}
 ----
-* '''Sep-09 We'''
+* '''Sep-16 We'''
+:{|
+| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]
+|''' Why are permeabilized muscle fibers (pfi) a poor sample type for studying reactive oxygen species (ROS) production?  '''<br>
+In experiments with pfi, high oxygen concentrations are needed to avoid oxygen limitation. However, the high oxygen pressures used may artificially increase ROS, including H<sub>2</sub>O<sub>2</sub> production, making pfi a less optimal model for ROS production studies. <br>
+- »'''[[Permeabilized_muscle_fibers#Oxygen_dependence_of_ROS_production_-_are_permeabilized_fibers_a_valid_model.3F|Oxygen dependence of ROS production in pfi]]'''« <br>
+- communicated by »[[Komlodi Timea]]« and »[[Cardoso Luiza]]«
+|}
 ----
-* '''Sep-10 Th'''
+* '''Sep-17 Th'''
 :{|
-| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]
+| width="110" align="center" | [[Image:SUIT icon.jpg|80px|link=https://wiki.oroboros.at/index.php/MitoPedia:_SUIT |MitoPedia: SUIT]]
-|''' What is the limitation of State 3 respiration compared to [[OXPHOS capacity]]? '''<br>
+|''' Did you know that you can measure the respiratory activity available for phosphorylation of ADP to ATP in living cells?'''<br>
-OXPHOS capacity is defined as the maximal respiratory capacity in the OXPHOS state in the presence of kinetically-saturating concentration of ADP, P<sub>i</sub>, fuel substrates and O<sub>2</sub>. However, State 3 as defined by Chance and Williams (1955) can lead to underestimation of OXPHOS capacity and overestimation of [[excess E-P capacity]] due to kinetic limitations of the phosphorylation system. <br>
+SUIT protocols from the [[SUIT-003]] family will guide you through the titrations needed to analyze [[free ROUTINE activity]].<br>
-- »'''[[BEC_2020.1_doi10.26124bec2020-0001.v1|BEC: Mitochondrial physiology]]'''« - Table 3 and several figures. <br>
+- »'''[[SUIT-003 O2 ce D009]]'''« and '''»[[SUIT-003 O2 ce-pce D020]]'''« <br>
-- communicated by » [[Cecatto Cristiane]] « and » [[Komlodi Timea]] «
+- communicated by »[[Cardoso Luiza]]« and »[[Komlodi Timea]]«
 |}
+----
+* '''Sep-18 Fr'''
+----
+* '''Sep-19 Sa'''
+----
+* '''Sep-20 So'''
+:::: [[File:ESCI.JPG|100px|link=https://wiki.oroboros.at/index.php/ESCI_2020_Virtual_Event]] <big>'''[[ESCI 2020 Virtual Event]]'''</big> Sep 20-30
 ----
-* '''Sep-11 Fr'''