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Difference between revisions of "Template:Current week ecosystem agenda"

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{{Template:Science for Ukraine}}
{{Template:Science for Ukraine}}
  2024 Week 06
  2024 Week 16


* '''Feb-05 Mo'''
* '''Apr-15 Mo'''  
:{|
:{|
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]
|'''"We demonstrated deficient platelet mitochondrial respiratory chain functions, oxidative phosphorylation (OXPHOS), and electron transfer (ET) capacity with complex I (CI)-linked substrates, and reduced [...] endogenous platelet coenzyme Q10 (CoQ10) concentration in UC [urothelial carcinoma] patients."''' <br>
|'''Do you observe either a zero or low raw O<sub>2</sub> signal when starting a measurement?'''<br>
* Palacka P, Gvozdjáková A, Rausová Z, Kucharská J, Slopovský J, Obertová J, Furka D, Furka S, Singh KK, Sumbalová Z (2021) Platelet mitochondrial bioenergetics reprogramming in patients with urothelial carcinoma. [[Palacka 2021 Int J Mol Sci|»Bioblast link«]]
Perform a test to evaluate whether this is related to an improperly positioned chamber or a faulty connection between the OroboPOS and the OroboPOS-Connector. <br>
:from the O2k-Network »[[SK Bratislava Sumbalova Z]]«
- »'''[https://wiki.oroboros.at/index.php/Oxygen_signal#Raw_signal Oxygen signal]'''«<br>
- communicated by »[[Grings Mateus]]« and »[[Schmitt Sabine]]«
|}
|}
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* '''Feb-06 Tu'''  
* '''Apr-16 Tu'''  
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* '''Feb-07 We'''  
* '''Apr-17 We'''  
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* '''Feb-08 Th'''  
* '''Apr-18 Th'''  
 
:{|
:{|
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]
|'''Can I use the same stock solutions for all reagents for different O2k-chamber volumes?'''<br>
|''' How to store the POS overnight and up to several months? '''<br>
"For some reagents, the concentration of the stock solution differs between the 2.0-mL and the 0.5-mL chamber (O2k-sV-Module) to facilitate a precise volume titration."<br>
With the POS still in place, fill the O2k-chamber and receptacle of the loosely inserted stopper with 70 % EtOH, add the Cover-slip and switch off the O2K. <br>
-»'''[[MiPNet09.12 O2k-Titrations]]'''«<br>
- »'''[[MiPNet19.03 O2k-cleaning and ISS]]'''«<br>
- communicated by »[[Timon-Gomez Alba]]« and »[[Leo Elettra]]«
- communicated by »[[Leo Elettra]]« and »[[Grings Mateus]]«
|}
|}
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* '''Feb-09 Fr'''  
* '''Apr-19 Fr'''
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'''<big>Next Week</big>'''
'''<big>Next Week</big>'''
  2024 Week 07
  2024 Week 17


* '''Feb-12 Mo'''
* '''Apr-22 Mo'''
:{|
:{|
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]
|''' What is the O<sub>2</sub> solubility factor of the medium (''F''<sub>M</sub>) and why is it important? '''<br>
|'''How can I evaluate the effect of one specific titration of a complex SUIT protocol?'''<br>
''F''<sub>M</sub> expresses the effect of the salt concentration on oxygen solubility relative to pure water, and varies depending on the temperature and composition of the medium. The correct ''F''<sub>M</sub> needs to be entered in DatLab when performing an air calibration. <br>
Flux control efficiencies express the change in respiration after a single step, in which there is a change in a metabolic control variable.<br>
- »'''[[Oxygen solubility factor]]'''« , »'''[[Oxygen_calibration_-_DatLab#Air_calibration_in_DatLab|Air calibration in DatLab]]'''« <br>
- »'''[[Flux control efficiency]]'''«, »'''[[Metabolic control variable]]'''«<br>
- communicated by »[[Baglivo Eleonora]]« and »[[Timon-Gomez Alba]]«  
- communicated by »[[Cardoso Luiza]]« and »[[Baglivo Eleonora]]«  
|}
|}
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* '''Feb-13 Tu'''  
* '''Apr-23 Tu'''  
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* '''Feb-14 We'''  
* '''Apr-24 We'''  
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* '''Feb-15 Th''' - International Childhood Cancer Day
* '''Apr-25 Th'''
:{|
:{|
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]
|'''"Deleterious mtDNA mutations contribute significantly to the tumorigenesis of pediatric cancers"''' <br>
|'''"Our results further enhance the understanding and relevance of bioenergetic function in liver ischemia and transplantation and provide the basis for further consideration of these parameters as biomarkers in LT [liver transplantation]."''' <br>
* Triska P, Kaneva K, Merkurjev D, Sohail N, Falk MJ, Triche TJ Jr, Biegel JA, Gai X (2019) Landscape of germline and somatic mitochondrial DNA mutations in pediatric malignancies. [[Triska 2019 Cancer Res|»Bioblast link«]]
* Meszaros AT, Weissenbacher A, Schartner M, Egelseer-Bruendl T, Hermann M, Unterweger J, Mittelberger C, Reyer BA, Hofmann J, Zelger BG, Hautz T, Resch T, Margreiter C, Maglione M, Komlódi T, Ulmer H, Cardini B, Troppmair J, Öfner D, Gnaiger E, Schneeberger S, Oberhuber R (2024) The predictive value of graft viability and bioenergetics testing towards the outcome in liver transplantation. [[Meszaros_2024_Transpl_Int|»Bioblast link«]]
:from the O2k-Network »[[US_PA_Philadelphia_Falk_MJ]]«
:from the O2k-Network »[[AT Innsbruck Schneeberger S]] and [[AT Innsbruck Oroboros]]«
|}
|}  
 
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* '''Feb-16 Fr'''  
* '''Apr-26 Fr'''
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Revision as of 14:02, 15 April 2024

Gentle Science
Oroboros declares solidarity against the Russian aggression-war in Ukraine and against all aggression-wars worldwide. -  »More details
A future for Ukraine is the future of its science
2024 Week 16
  • Apr-15 Mo
O2k-Open SupportInfo: improve Do you observe either a zero or low raw O2 signal when starting a measurement?

Perform a test to evaluate whether this is related to an improperly positioned chamber or a faulty connection between the OroboPOS and the OroboPOS-Connector.
- »Oxygen signal«
- communicated by »Grings Mateus« and »Schmitt Sabine«


  • Apr-16 Tu

  • Apr-17 We

  • Apr-18 Th
O2k-Open SupportInfo: improve How to store the POS overnight and up to several months?

With the POS still in place, fill the O2k-chamber and receptacle of the loosely inserted stopper with 70 % EtOH, add the Cover-slip and switch off the O2K.
- »MiPNet19.03 O2k-cleaning and ISS«
- communicated by »Leo Elettra« and »Grings Mateus«


  • Apr-19 Fr

Next Week

2024 Week 17
  • Apr-22 Mo
MitoPedia
How can I evaluate the effect of one specific titration of a complex SUIT protocol?

Flux control efficiencies express the change in respiration after a single step, in which there is a change in a metabolic control variable.
- »Flux control efficiency«, »Metabolic control variable«
- communicated by »Cardoso Luiza« and »Baglivo Eleonora« 


  • Apr-23 Tu

  • Apr-24 We

  • Apr-25 Th
O2k-Publications in the MiPMap "Our results further enhance the understanding and relevance of bioenergetic function in liver ischemia and transplantation and provide the basis for further consideration of these parameters as biomarkers in LT [liver transplantation]."
  • Meszaros AT, Weissenbacher A, Schartner M, Egelseer-Bruendl T, Hermann M, Unterweger J, Mittelberger C, Reyer BA, Hofmann J, Zelger BG, Hautz T, Resch T, Margreiter C, Maglione M, Komlódi T, Ulmer H, Cardini B, Troppmair J, Öfner D, Gnaiger E, Schneeberger S, Oberhuber R (2024) The predictive value of graft viability and bioenergetics testing towards the outcome in liver transplantation. »Bioblast link«
from the O2k-Network »AT Innsbruck Schneeberger S and AT Innsbruck Oroboros«

  • Apr-26 Fr