Difference between revisions of "Template:Current week ecosystem agenda"

Revision as of 14:02, 15 April 2024

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-» A future for Ukraine is the future of its science

2024 Week 16

Apr-15 Mo

Do you observe either a zero or low raw O₂ signal when starting a measurement?

Perform a test to evaluate whether this is related to an improperly positioned chamber or a faulty connection between the OroboPOS and the OroboPOS-Connector.
- »Oxygen signal«
- communicated by »Grings Mateus« and »Schmitt Sabine«

Apr-16 Tu

Apr-17 We

Apr-18 Th

How to store the POS overnight and up to several months?

With the POS still in place, fill the O2k-chamber and receptacle of the loosely inserted stopper with 70 % EtOH, add the Cover-slip and switch off the O2K.
- »MiPNet19.03 O2k-cleaning and ISS«
- communicated by »Leo Elettra« and »Grings Mateus«

Apr-19 Fr

Next Week

2024 Week 17

Apr-22 Mo

How can I evaluate the effect of one specific titration of a complex SUIT protocol?

Flux control efficiencies express the change in respiration after a single step, in which there is a change in a metabolic control variable.
- »Flux control efficiency«, »Metabolic control variable«
- communicated by »Cardoso Luiza« and »Baglivo Eleonora«

Apr-23 Tu

Apr-24 We

Apr-25 Th

"Our results further enhance the understanding and relevance of bioenergetic function in liver ischemia and transplantation and provide the basis for further consideration of these parameters as biomarkers in LT [liver transplantation]."

Meszaros AT, Weissenbacher A, Schartner M, Egelseer-Bruendl T, Hermann M, Unterweger J, Mittelberger C, Reyer BA, Hofmann J, Zelger BG, Hautz T, Resch T, Margreiter C, Maglione M, Komlódi T, Ulmer H, Cardini B, Troppmair J, Öfner D, Gnaiger E, Schneeberger S, Oberhuber R (2024) The predictive value of graft viability and bioenergetics testing towards the outcome in liver transplantation. »Bioblast link«

from the O2k-Network »AT Innsbruck Schneeberger S and AT Innsbruck Oroboros«

Apr-26 Fr

@@ Line 1: / Line 1: @@
 {{Template:Science for Ukraine}}
-Week 10
+Week 16
-* '''Mar-04 Mo'''
+* '''Apr-15 Mo'''
 :{|
 | width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]
-|''' Do you observe an unstable O<sub>2</sub> slope negative following TIP2k titrations during an instrumental O<sub>2</sub> background test?  '''<br>
+|'''Do you observe either a zero or low raw O<sub>2</sub> signal when starting a measurement?'''<br>
-Incorrect placement of TIP2k Filter Papers can lead to liquid accumulation and convective oxygen backdiffusion. Check for proper placement by confirming they are fully in contact with the stopper receptacle.
+Perform a test to evaluate whether this is related to an improperly positioned chamber or a faulty connection between the OroboPOS and the OroboPOS-Connector. <br>
-<br>
+- »'''[https://wiki.oroboros.at/index.php/Oxygen_signal#Raw_signal Oxygen signal]'''«<br>
-- »'''[[MiPNet14.06_Instrumental_O2_background|Instrumental O<sub>2</sub> background]]'''«, »'''[https://wiki.oroboros.at/index.php/Oxygen_flux_-_instrumental_background#Unstable_O2_slope_neg._in_instrumental_background_test Unstable O<sub>2</sub> slope negative]'''«<br>
+- communicated by »[[Grings Mateus]]« and »[[Schmitt Sabine]]«
-- communicated by »[[Grings Mateus]]« and »[[Baglivo Eleonora]]«
 |}
 ----
-* '''Mar-05 Tu'''
+* '''Apr-16 Tu'''
 ----
-* '''Mar-06 We'''
+* '''Apr-17 We'''
-:{|
-| width="100" align="center" |[[File:BEC2024.1.jpg|right|150px|link=https://doi.org/10.26124/bec:2024-0001 |Gross 2024 BEC]]
-|'''The tale of two “best-friends,” proteins BID & MTCH2, pivotal regulators of the apoptosis and metabolism programs at the mitochondria.''' <br>
-* Gross A, (2024) A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part? Bioenerg Commun 2024.1. https://doi.org/10.26124/bec:2024-0001
-|}
 ----
-* '''Mar-07 Th'''
+* '''Apr-18 Th'''
 :{|
 | width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]
-|''' Which medium can be used for the instrumental background test?'''<br>
+|''' How to store the POS overnight and up to several months? '''<br>
-When using dithionite, the instrumental background test should be performed in mitochondrial respiration medium MiR05, MiR05-Kit or MiR06; or alternatively, in a strong alkaline phosphate buffer (>100 mM; >pH 8), to avoid side reactions that might interfere with the test.<br>
+With the POS still in place, fill the O2k-chamber and receptacle of the loosely inserted stopper with 70 % EtOH, add the Cover-slip and switch off the O2K. <br>
-- »'''[[MiPNet14.06_Instrumental_O2_background]]'''«<br>
+- »'''[[MiPNet19.03 O2k-cleaning and ISS]]'''«<br>
-- communicated by »[[Schmitt Sabine]]« and »[[Timon-Gomez Alba]]«
+- communicated by »[[Leo Elettra]]« and »[[Grings Mateus]]«
 |}
 ----
-* '''Mar-08 Fr'''
+* '''Apr-19 Fr'''
 ----
 '''<big>Next Week</big>'''
-Week 11
+Week 17
-* '''Mar-11 Mo'''
+* '''Apr-22 Mo'''
 :{|
 | width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]
-|''' Why is it important to perform respirometry with permeabilized muscle fibers (pfi) under a high [O<sub>2</sub>] regime? '''<br>
+|'''How can I evaluate the effect of one specific titration of a complex SUIT protocol?'''<br>
-Long diffusion distances in the pfi result in an O<sub>2</sub> diffusion limitation, which is overcome by increasing the O<sub>2</sub> partial pressure inside the chamber. Proper instrumental background correction is a must and O<sub>2</sub> dependence of ROS production should be considered.   <br>
+Flux control efficiencies express the change in respiration after a single step, in which there is a change in a metabolic control variable.<br>
-- »'''[[Permeabilized muscle fibers]]'''«, »'''[[Oxygen flux - instrumental background]]'''« <br>
+- »'''[[Flux control efficiency]]'''«, »'''[[Metabolic control variable]]'''«<br>
-- communicated by »[[Grings Mateus]]« and »[[Cardoso Luiza]]«
+- communicated by »[[Cardoso Luiza]]« and »[[Baglivo Eleonora]]«
 |}
 ----
-* '''Mar-12 Tu'''
+* '''Apr-23 Tu'''
 ----
-* '''Mar-13 We'''
+* '''Apr-24 We'''
-:{|
-| width="100" align="center" |[[Image:BEC-logo.png|100px|link=https://www.bioenergetics-communications.org/index.php/bec |Bioenergetics Communications]]
-|'''''Rewarded'' Open Access - compensating authors..'''<br>
-Together with the MiP''society'', BEC is raising funds to reward the first 10 papers accepted for publication in BEC in 2024: 600 EUR to attend EBEC2024 and 2-year MiP''membership''.
--»[https://whydonate.com/en/fundraising/BEC Support open access in science]«<br>
-- »[https://www.bioenergetics-communications.org/index.php/bec/about/submissions Submit a manuscript]«
-|}
 ----
-* '''Mar-14 Th'''
+* '''Apr-25 Th'''
 :{|
 | width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]
-|'''Mitochondrial ultrastructure and respiration are affected during EDL [''Extensor digitorum longus'' muscle] aging.''' <br>
+|'''"Our results further enhance the understanding and relevance of bioenergetic function in liver ischemia and transplantation and provide the basis for further consideration of these parameters as biomarkers in LT [liver transplantation]."''' <br>
-* Fernando R, Shindyapina AV, Ost M, Santesmasses D, Hu Y, Tyshkovskiy A, Yim SH, Weiss J, Gladyshev VN, Grune T, Castro JP (2023) Downregulation of mitochondrial metabolism is a driver for fast skeletal muscle loss during mouse aging.  [[Fernando 2023 Commun Biol|»Bioblast link«]]
+* Meszaros AT, Weissenbacher A, Schartner M, Egelseer-Bruendl T, Hermann M, Unterweger J, Mittelberger C, Reyer BA, Hofmann J, Zelger BG, Hautz T, Resch T, Margreiter C, Maglione M, Komlódi T, Ulmer H, Cardini B, Troppmair J, Öfner D, Gnaiger E, Schneeberger S, Oberhuber R (2024) The predictive value of graft viability and bioenergetics testing towards the outcome in liver transplantation.  [[Meszaros_2024_Transpl_Int|»Bioblast link«]]
-:from the O2k-Network »[[DE Leipzip Ost M]]«
+:from the O2k-Network »[[AT Innsbruck Schneeberger S]] and [[AT Innsbruck Oroboros]]«
 |}
 ----
-* '''Mar-15 Fr'''
+* '''Apr-26 Fr'''
 ----