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Revision as of 09:17, 28 August 2023

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2023 Week 35

Aug- 28 Mo

Can I compare data sets recorded with different sensor gain settings?

Oxygen signals obtained after proper calibration are independent of the gain settings, therefore oxygen concentrations (and fluxes) can be compared, as long as the corresponding air and zero calibrations are applied.
- »Gain of the O2 channel«
- communicated by »Baglivo Eleonora« and »Leo Elettra«

Aug- 29 Tu

"Altogether, our results show that chronic hypoxia optimizes the efficiency of mitochondrial ATP synthesis in the retrosplenial cortex of mice. Contrastingly, rats sustain the production of ATP only by increasing mitochondrial content and altering mitochondrial dynamics, suggesting drastic mitochondrial malfunctions."

Arias-Reyes C, Aliaga-Raduán F, Pinto-Aparicio R, Joseph V, Soliz J (2023) Mitochondrial plasticity in the retrosplenial cortex enhances ATP synthesis during acclimatization to hypoxia in mice but not in rats. MitoFit Preprints 2023.6. https://doi.org/10.26124/mitofit:2023-0006

from the O2k-Network »CA Quebec Soliz J«

Aug- 30 We

Aug- 31 Th

"Our study showed that salinity modulates the mitochondrial responses to long-term and acute hypoxia exposure in an euryhaline intertidal bivalve C. gigas."

Steffen JBM, Sokolov EP, Sokolova IM (2023) Combined effects of salinity and intermittent hypoxia on mitochondrial capacity and reactive oxygen species efflux in the Pacific oyster, Crassostrea gigas »Bioblast link«

from the O2k-Network »DE Rostock Sokolova I«

Sep- 01 Fr

@@ Line 1: / Line 1: @@
 {{Template:Science for Ukraine}}
-Week 34
+Week 35
-*'''Aug- 21 Mo'''
+*'''Aug- 28 Mo'''
+:{|
+| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]
+|''' Can I compare data sets recorded with different sensor gain settings? '''<br>
+Oxygen signals obtained after proper calibration are independent of the gain settings, therefore oxygen concentrations (and fluxes) can be compared, as long as the corresponding air and zero calibrations are applied.
+<br>
+- »'''[[Gain#Gain: O2 channel of the O2k|Gain of the O2 channel]]'''«<br>
+- communicated by »[[Baglivo Eleonora]]« and »[[Leo Elettra]]«
+|}
 ----
-*'''Aug- 22 Tu'''
+*'''Aug- 29 Tu'''
 :{|
-| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]
+| width="100" align="center" |[[File:MitoFit Preprints.png|100px|link=https://wiki.oroboros.at/images/1/19/Arias-Reyes_2023_MitoFit.pdf |MitoFit pdf]]
-|''' Are pyruvate, glutamate, and malate substrates of Complex I?'''<br>
+|'''"Altogether, our results show that chronic hypoxia optimizes the efficiency of mitochondrial ATP synthesis in the retrosplenial cortex of mice. Contrastingly, rats sustain the production of ATP only by increasing mitochondrial content and altering mitochondrial dynamics, suggesting drastic mitochondrial malfunctions."'''<br>
-No, NADH is a Complex I substrate. However, pyruvate, glutamate and malate are used in high-resolution respirometry as substrates for mitochondrial dehydrogenases to generate NADH in the mitochondrial matrix because NADH cannot cross the mitochondrial inner membrane. <br>
+* Arias-Reyes C, Aliaga-Raduán F, Pinto-Aparicio R, Joseph V, Soliz J (2023) Mitochondrial plasticity in the retrosplenial cortex enhances ATP synthesis during acclimatization to hypoxia in mice but not in rats. MitoFit Preprints 2023.6. https://doi.org/10.26124/mitofit:2023-0006
-- »'''[[NADH electron transfer-pathway state]]'''« and »'''[[Complex I]]'''« <br>
+:from the O2k-Network »[[CA Quebec Soliz J]]«
-- communicated by »[[Cardoso Luiza]]« and »[[Grings Mateus]]«
 |}
 ----
-*'''Aug- 23 We'''
+*'''Aug- 30 We'''
 ----
-*'''Aug- 24 Th'''
+*'''Aug- 31 Th'''
 :{|
-| width="100" align="center" |[[File:FAT4BRAIN logo.png|80px|link=https://wiki.oroboros.at/index.php/FAT4BRAIN |FAT4BRAIN]]
+| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]
-|'''"Understanding acylcarnitine metabolic and signaling pathways provides a better rationale for selecting targets for therapeutic interventions."''' <br>
+|'''"Our study showed that salinity modulates the mitochondrial responses to long-term and acute hypoxia exposure in an euryhaline intertidal bivalve ''C. gigas''."''' <br>
-* Dambrova M, Makrecka-Kuka M, Kuka J, Vilskersts R, Nordberg D, Attwood MM, Smesny S, Sen ZD, Guo AC, Oler E, Tian S, Zheng J, Wishart DS, Liepinsh E, Schioth HB. (2022) Acylcarnitines: Nomenclature, Biomarkers, Therapeutic Potential, Drug Targets, and Clinical Trials.  [[Dambrova 2022 Pharmacol Rev|»Bioblast link«]]
+*Steffen JBM, Sokolov EP, Sokolova IM (2023) Combined effects of salinity and intermittent hypoxia on mitochondrial capacity and reactive oxygen species efflux in the Pacific oyster, ''Crassostrea gigas''  [[Steffen 2023 J Exp Biol|»Bioblast link«]]
-:from the O2k-Network »[[LV Riga Liepins E]]«
+:from the O2k-Network »[[DE Rostock Sokolova I]]«
 |}
 ----
-*'''Aug- 25 Fr'''
+*'''Sep- 01 Fr'''
 ----