Template:Keywords: Coupling control: Difference between revisions
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== Mitochondrial and cellular respiratory rates in coupling control states == | == Mitochondrial and cellular respiratory rates in coupling control states == | ||
:::: [[File:P.jpg |link=OXPHOS capacity]] [[OXPHOS capacity]] ''P'' | :::: [[File:P.jpg |link=OXPHOS-capacity]] [[OXPHOS-capacity]] ''P'' | ||
:::: [[File:R.jpg |link=ROUTINE respiration]] [[ROUTINE respiration]] ''R'' | :::: [[File:R.jpg |link=ROUTINE-respiration]] [[ROUTINE-respiration]] ''R'' | ||
:::: [[File:E.jpg |link=ET capacity]] [[ET capacity]] ''E'' | :::: [[File:E.jpg |link=ET-capacity]] [[ET-capacity]] ''E'' | ||
:::: [[File:L.jpg |link=LEAK respiration]] [[LEAK respiration]] ''L'' | :::: [[File:L.jpg |link=LEAK-respiration]] [[LEAK-respiration]] ''L'' | ||
:::: [[File:ROX.jpg |link=Residual oxygen consumption]] [[Residual oxygen consumption]] ''Rox'' | :::: [[File:ROX.jpg |link=Residual oxygen consumption]] [[Residual oxygen consumption]] ''Rox'' | ||
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== General == | == General == | ||
::::» [[Basal respiration]] | |||
::::» [[Dyscoupling]] | |||
::::» [[ET-coupling efficiency]] | ::::» [[ET-coupling efficiency]] | ||
::::» [[Flux control efficiency]] | ::::» [[Flux control efficiency]] | ||
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::::» [[Oxygen flow]] | ::::» [[Oxygen flow]] | ||
::::» [[Oxygen flux]] | ::::» [[Oxygen flux]] | ||
::::» [[Permeabilized cells]] | |||
::::» [[Respiratory acceptor control ratio]] RCR | ::::» [[Respiratory acceptor control ratio]] RCR | ||
::::» [[Uncoupling]] | ::::» [[Uncoupling]] | ||
Revision as of 01:53, 9 November 2020
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Mitochondrial and cellular respiratory rates in coupling control states
- L/P coupling control ratio, L/P
- L/R coupling control ratio, L/R
- LEAK-control ratio, L/E
- OXPHOS-control ratio, P/E
- ROUTINE-control ratio, R/E
- Net OXPHOS-control ratio, (P-L)/E
- Net ROUTINE-control ratio, (R-L)/E
Net, excess, and reserve capacities of respiration
- Net OXPHOS-capacity P-L, P-L
- Net ROUTINE-activity R-L, R-L
- Net ET-capacity E-L, E-L
- ET-excess capacity E-P, E-P
- ET-reserve capacity E-R, E-R
- OXPHOS-coupling efficiency P-L, (P-L)/P = 1-L/P
- ROUTINE-coupling efficiency R-L, (R-L)/R = 1-L/R
- ET-coupling efficiency E-L, (E-L)/E = 1-L/E
- ET-excess control efficiency E-P, (E-P)/E = 1-P/E
- ET-reserve control efficiency E-R, (E-R)/E = 1-R/E
General
The Blue Book 2020
OXPHOS-, ROUTINE-, ET-, and LEAK states; respiratory capacities (P, R, E, L) corrected for residual oxygen consumption Rox.
4-compartmental OXPHOS model. (1) ET capacity E of the noncoupled electron transfer system ETS. OXPHOS capacity P is partitioned into (2) the dissipative LEAK component L, and (3) ADP-stimulated P-L net OXPHOS capacity. (4) If P-L is kinetically limited by a low capacity of the phosphorylation system to utilize the protonmotive force pmF, then the apparent E-P excess capacity is available to drive coupled processes other than phosphorylation P» (ADP to ATP) without competing with P».
(P-L)/P is the OXPHOS P-L control efficiency. The biochemical coupling efficiency is independent of kinetic control by the phosphorylation system when expressed as the E-L coupling efficiency, (E-L)/E. (E-P)/E is the kinetic E-P control efficiency.
