Triethyltin bromide: Difference between revisions
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{{MitoPedia | {{MitoPedia | ||
|abbr=TET | |abbr=TET | ||
|description=Triethyltin bromide (TET) is a lipophilic [1] inhibitor of the mitochondrial | |description=Triethyltin bromide (TET) is a lipophilic [1] inhibitor of the mitochondrial [[ATP synthase]] [2] which is used to induce [[LEAK state]] in [[living cells]] of ''Saccharomyces cerevisiae''. | ||
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Contributed by [[Kandolf G]] 2016-02-08 | |||
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Chemical formula: (C<sub>2</sub>H<sub>5</sub>)<sub>3</sub>SnBr Β | |||
Synonym: Bromotriethylstannane Β | Synonym: Bromotriethylstannane Β | ||
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#Cain K, Griffiths DE (1977) Studies of energy-linked reactions. Localization of the site of action of trialkyltin in yeast mitochondria. Biochem J 162:575-80. [http://www.biochemj.org/content/162/3/575.full-text.pdf Open Access]] | #Cain K, Griffiths DE (1977) Studies of energy-linked reactions. Localization of the site of action of trialkyltin in yeast mitochondria. Biochem J 162:575-80. [http://www.biochemj.org/content/162/3/575.full-text.pdf Open Access]] | ||
#Also see: Sundaram V, Petkova MI, Pujol-Carrion N, Boada J, de la Torre-Ruiz MA (2015) Tor1, Sch9 and PKA downregulation in quiescence rely on Mtl1 to preserve mitochondrial integrity and cell survival. Mol Microbiol 97:93-109. [[Sundaram 2015 Mol Microbiol|Bioblast Link]] | #Also see: Sundaram V, Petkova MI, Pujol-Carrion N, Boada J, de la Torre-Ruiz MA (2015) Tor1, Sch9 and PKA downregulation in quiescence rely on Mtl1 to preserve mitochondrial integrity and cell survival. Mol Microbiol 97:93-109. [[Sundaram 2015 Mol Microbiol|Bioblast Link]] | ||
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Latest revision as of 10:37, 11 September 2020
Description
Triethyltin bromide (TET) is a lipophilic [1] inhibitor of the mitochondrial ATP synthase [2] which is used to induce LEAK state in living cells of Saccharomyces cerevisiae.
Abbreviation: TET
Contributed by Kandolf G 2016-02-08
Chemical formula: (C2H5)3SnBr
Synonym: Bromotriethylstannane
References
- Aguilaniu H, Gustafsson L, Rigoulet M, NystrΓΆm T (2001) Protein oxidation in G0 cells of Saccharomyces cerevisiae depends on the state rather than rate of respiration and is enhanced in pos9 but not yap1 mutants. J Biol Chem 276:35396-404. Bioblast Link
- Cain K, Griffiths DE (1977) Studies of energy-linked reactions. Localization of the site of action of trialkyltin in yeast mitochondria. Biochem J 162:575-80. Open Access]
- Also see: Sundaram V, Petkova MI, Pujol-Carrion N, Boada J, de la Torre-Ruiz MA (2015) Tor1, Sch9 and PKA downregulation in quiescence rely on Mtl1 to preserve mitochondrial integrity and cell survival. Mol Microbiol 97:93-109. Bioblast Link
MitoPedia topics:
Inhibitor