Semantic search
From Bioblast
Year | Reference | Coupling | Pathway | Preparation | Organism | Tissue;cell | |
---|---|---|---|---|---|---|---|
Reda 2019 Sci Rep | 2019 | Reda A, Refaat A, Abd-Rabou AA, Mahmoud AM, Adel M, Sabet S, Ali SS (2019) Role of mitochondria in rescuing glycolytically inhibited subpopulation of triple negative but not hormone-responsive breast cancer cells. Sci Rep 9:13748. | LEAK OXPHOS | N S CIV ROX | Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell |
Skrivergaard 2019 Viruses | 2019 | Skrivergaard S, Jensen MS, Rolander TB, Nguyen TBN, Bundgaard A, Nejsum LN, Martensen PM (2019) The cellular localization of the p42 and p46 oligoadenylate synthetase 1 isoforms and their impact on mitochondrial respiration. Viruses 11:E1122. | LEAK ROUTINE OXPHOS ET | N S ROX | Permeabilized cells Intact cells | Human | Other cell lines HeLa |
D'Amico 2019 Mol Cell | 2019 | D'Amico D, Mottis A, Potenza F, Sorrentino V, Li H, Romani M, Lemos V, Schoonjans K, Zamboni N, Knott G, Schneider BL, Auwerx J (2019) The RNA-binding protein PUM2 impairs mitochondrial dynamics and mitophagy during aging. Mol Cell 73:775-87. | OXPHOS | S NS ROX | Homogenate | Mouse | Skeletal muscle |
Detaille 2019 PLoS One | 2019 | Detaille D, Pasdois P, Sémont A, Dos Santos P, Diolez P (2019) An old medicine as a new drug to prevent mitochondrial complex I from producing oxygen radicals. PLoS One 14:e0216385. | LEAK OXPHOS | N S NS ROX | Isolated mitochondria | Rat | Heart |
Brunetta 2019 J Funct Foods | 2019 | Brunetta HS, de Paula GC, Fritzen M, Cecchini MS, dos Santos GJ, Nazari EM, Rafacho A, de Bem AF, Nunes EA (2019) Leucine increases muscle mitochondrial respiration and attenuates glucose intolerance in diet-induced obesity in Swiss mice. J Funct Foods 62:103544. | LEAK OXPHOS | N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Gonzalez-Mariscal 2019 FASEB J | 2019 | González-Mariscal I, Montoro RA, O'Connell JF, Kim Y, Gonzalez-Freire M, Liu QR, Alfaras I, Carlson OD, Lehrmann E, Zhang Y, Becker KG, Hardivillé S, Ghosh P, Egan JM (2019) Muscle cannabinoid 1 receptor regulates Il-6 and myostatin expression, governing physical performance and whole-body metabolism. FASEB J 33:5850-63. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Electron-transfer-pathway state | 2019 | Gnaiger E (2019) ET-pathway states. Mitochondr Physiol Network 2019-06-11 (last edit since 2016-11-08). | LEAK OXPHOS ET | F N S Gp CIV NS Other combinations | Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria SMP | ||
Cesnekova 2019 Thesis | 2019 | Cesnekova J (2019) Functional characterization of LACE1 APTase and mitochondrial AAA proteases YME1L and AFG3L2 in mitochondrial protein homeostasis. PhD Thesis 133. | OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Human | HEK |
Dall 2019 J Biol Chem | 2019 | Dall M, Trammell SAJ, Asping M, Hassing AS, Agerholm M, Vienberg SG, Gillum MP, Larsen S, Treebak JT (2019) Mitochondrial function in liver cells is resistant to perturbations in NAD+ salvage capacity. J Biol Chem 294:13304-26. | LEAK OXPHOS ET | F N S | Intact cells | Mouse | Liver |
Dilberger 2019 Oxid Med Cell Longev | 2019 | Dilberger B, Baumanns S, Schmitt F, Schmiedl T, Hardt M, Wenzel U, Eckert GP (2019) Mitochondrial oxidative stress impairs energy metabolism and reduces stress resistance and longevity of C. elegans. Oxid Med Cell Longev 2019:6840540. | LEAK ROUTINE ET | N S CIV NS | Isolated mitochondria | Caenorhabditis elegans | |
Chiba 2019 J Am Soc Nephrol | 2019 | Chiba T, Peasley KD, Cargill KR, Maringer KV, Bharathi SS, Mukherjee E, Zhang Y, Holtz A, Basisty N, Yagobian SD, Schilling B, Goetzman ES, Sims-Lucas S (2019) Sirtuin 5 regulates proximal tubule fatty acid oxidation to protect against AKI. J Am Soc Nephrol 30:2384-98. | OXPHOS | N S | Homogenate | Mouse | Kidney |
Garrido-Maraver 2019 Cell Death Dis | 2019 | Garrido-Maraver J, Celardo I, Costa AC, Lehmann S, Loh SHY, Martins LM (2019) Enhancing folic acid metabolism suppresses defects associated with loss of Drosophila mitofusin. Cell Death Dis 10:288. | OXPHOS ET | N S | Permeabilized tissue | Drosophila | |
Dannheisig 2019 Cells | 2019 | Dannheisig DP, Beck E, Calzia E, Walther P, Behrends C, Pfister AS (2019) Loss of Peter Pan (PPAN) affects mitochondrial homeostasis and autophagic flux. Cells 8:E894. | LEAK ROUTINE ET | N S CIV NS ROX | Intact cells Permeabilized cells | Human | HeLa |
Nold 2019 Psychoneuroendocrinology | 2019 | Nold V, Sweatman C, Karabatsiakis A, Böck C, Bretschneider T, Lawless N, Fundel-Clemens K, Kolassa IT, Allers KA (2019) Activation of the kynurenine pathway and mitochondrial respiration to face allostatic load in a double-hit model of stress. Psychoneuroendocrinology 107:148-59. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Homogenate | Rat | Nervous system |
Perry 2019 J Mol Cell Cardiol | 2019 | Perry JB, Davis GN, Allen ME, Makrecka-Kuka M, Dambrova M, Grange RW, Shaikh SR, Brown DA (2019) Cardioprotective effects of idebenone do not involve ROS scavenging: Evidence for mitochondrial complex I bypass in ischemia/reperfusion injury. J Mol Cell Cardiol 135:160-171. | LEAK OXPHOS | N S ROX | Isolated mitochondria Permeabilized cells | Rat | Heart |
Berg 2019 Front Physiol | 2019 | Berg J, Undebakke V, Rasch-Halvorsen Ø, Aakerøy L, Sandbakk Ø, Tjønna AE (2019) Comparison of mitochondrial respiration in M. triceps brachii and M. vastus lateralis between elite cross-country skiers and physically active controls. Front Physiol 10:365. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Woodman 2019 Cardiovasc Res | 2019 | Woodman AG, Mah R, Keddie DL, Noble RMN, Holody CD, Panahi S, Gragasin FS, Lemieux H, Bourque SL (2019) Perinatal iron deficiency and a high salt diet cause long-term kidney mitochondrial dysfunction and oxidative stress. Cardiovasc Res 116:183-92. | LEAK OXPHOS ET | N S CIV NS | Homogenate | Rat | Kidney |
Long 2019 Methods Mol Biol | 2019 | Long Q, Huang L, Huang K, Yang Q (2019) Assessing mitochondrial bioenergetics in isolated mitochondria from mouse heart tissues using Oroboros Oxygraph-2k. Methods Mol Biol 1966:237-46. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Heart |
Latham 2019 J Anim Sci | 2019 | Latham CM, Fenger CK, White SH (2019) Rapid Communication: Differential skeletal muscle mitochondrial characteristics of weanling racing-bred horses. J Anim Sci [Epub ahead of print]. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Horse | Skeletal muscle |
Bianco 2019 PLoS One | 2019 | Bianco M, Lopes JA, Beiral HJV, Filho JDD, Frankenfeld SP, Fortunato RS, Gattass CR, Vieyra A, Takiya CM (2019) The contralateral kidney presents with impaired mitochondrial functions and disrupted redox homeostasis after 14 days of unilateral ureteral obstruction in mice. PLoS One 14:e0218986. | LEAK OXPHOS ET | N S | Isolated mitochondria | Mouse | Kidney |
Ferreira 2019 EMBO J | 2019 | Ferreira N, Perks KL, Rossetti G, Rudler DL, Hughes LA, Ermer JA, Scott LH, Kuznetsova I, Richman TR, Narayana VK, Abudulai LN, Shearwood AJ, Cserne Szappanos H, Tull D, Yeoh GC, Hool LC, Filipovska A, Rackham O (2019) Stress signaling and cellular proliferation reverse the effects of mitochondrial mistranslation. EMBO J 38:e102155. | LEAK OXPHOS ET | N S | Isolated mitochondria | Mouse | Heart Liver |
Yan 2019 Int Immunopharmacol | 2019 | Yan M, Yu Y, Mao X, Feng J, Wang Y, Chen H, Xie K, Yu Y (2019) Hydrogen gas inhalation attenuates sepsis-induced liver injury in a FUNDC1-dependent manner. Int Immunopharmacol 71:61-7. | LEAK OXPHOS | S | Isolated mitochondria | Mouse | Liver |
Lozano 2019 Oxid Med Cell Longev | 2019 | Lozano O, Lázaro-Alfaro A, Silva-Platas C, Oropeza-Almazán Y, Torres-Quintanilla A, Bernal-Ramírez J, Alves-Figueiredo H, García-Rivas G (2019) Nanoencapsulated quercetin improves cardioprotection during hypoxia-reoxygenation injury through preservation of mitochondrial function. Oxid Med Cell Longev 2019:7683051. | ET | S | Permeabilized cells | Rat | Skeletal muscle |
Bittel 2019 Diabetologia | 2019 | Bittel AJ, Bittel DC, Mittendorfer B, Patterson BW, Okunade AL, Yoshino J, Porter LC, Abumrad NA, Reeds DN, Cade WT (2019) A single bout of resistance exercise improves postprandial lipid metabolism in overweight/obese men with prediabetes. Diabetologia 63:611-23. | LEAK OXPHOS ET | F N S NS | Permeabilized tissue | Human | Skeletal muscle |
Campos 2019 Thesis | 2019 | Campos DF (2019) Os peixes amazônicos vivem perto dos seus limites térmicos? O efeito das mudanças climáticas sobre a ecofisiologia de peixes de Igarapé da Amazônia Central. PhD Thesis 106. | LEAK OXPHOS ET | N S CIV NS ROX | Intact cells | Fishes | Lung;gill |
Mazaki 2019 Biochem Biophys Res Commun | 2019 | Mazaki Y, Takada S, Nio-Kobayashi J, Maekawa S, Higashi T, Onodera Y, Sabe H (2019) Mitofusin 2 is involved in chemotaxis of neutrophil-like differentiated HL-60 cells. Biochem Biophys Res Commun 513:708-13. | OXPHOS | N S | Permeabilized cells | Human | Blood cells |
De Moura Escobar 2019 Toxicol In Vitro | 2019 | de Moura Escobar SJ, Simone M, de Oliveira Ribeiro CA, Martinez GR, Winnischofer SMB, Witting PK, Rocha MEM (2019) Cytotoxic effects of 4'-hydroxychalcone on human neuroblastoma cells (SH-SY5Y). Toxicol In Vitro 61:104640. | LEAK OXPHOS | N S ROX | Permeabilized cells | Human | Neuroblastoma |
Weinstein 2019 bioRxiv | 2019 | Weinstein RN, Crawford DL (2019) Effect of EBV-transformation on oxidative phosphorylation physiology in human cell lines. bioRxiv doi: https://doi.org/10.1101/2019.12.16.878025 . | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Human | Other cell lines Lymphocyte |
Hedges 2019 Comp Biochem Physiol A Mol Integr Physiol | 2019 | Hedges CP, Wilkinson RT, Devaux JBL, Hickey AJR (2019) Hymenoptera flight muscle mitochondrial function: Increasing metabolic power increases oxidative stress. Comp Biochem Physiol A Mol Integr Physiol 230:115-21. | OXPHOS ET LEAK | N S Gp CIV NS ROX | Permeabilized tissue | Other invertebrates | Skeletal muscle |
Robinson 2019 Am J Physiol Cell Physiol | 2019 | Robinson MM, Sather BK, Burney ER, Ehrlicher SE, Stierwalt HD, Franco MC, Newsom SA (2019) Robust intrinsic differences in mitochondrial respiration and H2O2 emission between L6 and C2C12 cells. Am J Physiol Cell Physiol 317:C339-C347. | LEAK OXPHOS ET | F N S Gp NS Other combinations ROX | Permeabilized cells | Mouse Rat | Skeletal muscle |
Mayeuf-Louchart 2019 Cell Rep | 2019 | Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H (2019) Glycogen dynamics drives lipid droplet biogenesis during brown adipocyte differentiation. Cell Rep 29:1410-18. | LEAK OXPHOS | F N S NS | Permeabilized cells | Mouse | Fat |
Havird 2019 Mitochondrion | 2019 | Havird JC, Noe GR, Link L, Torres A, Logan DC, Sloan DB, Chicco AJ (2019) Do angiosperms with highly divergent mitochondrial genomes have altered mitochondrial function? Mitochondrion 49:1-11. | LEAK OXPHOS | N S CIV NS ROX | Isolated mitochondria | Plants | |
Chroeis 2019 Basic Clin Pharmacol Toxicol | 2019 | Chroeis KM, Larsen S, Pedersen JS, Rygg MO, Boilsen AEB, Bendtsen F, Dela F (2019) Acetaminophen toxicity induces mitochondrial complex I inhibition in human liver tissue. https://doi.org/10.1111/bcpt.13304 | LEAK OXPHOS | N S ROX | Intact cells | Human | Liver |
Devaux 2019 J Exp Biol | 2019 | Devaux JBL, Hickey AJR, Renshaw GMC (2019) Mitochondrial plasticity in the cerebellum of two anoxia-tolerant sharks: contrasting responses to anoxia/reoxygenation. J Exp Biol 222:jeb191353. | LEAK ROUTINE OXPHOS ET | N S NS | Homogenate | Fishes | Nervous system |
Heden 2019 Sci Adv | 2019 | Heden TD, Johnson JM, Ferrara PJ, Eshima H, Verkerke ARP, Wentzler EJ, Siripoksup P, Narowski TM, Coleman CB, Lin CT, Ryan TE, Reidy PT, de Castro Brás LE, Karner CM, Burant CF, Maschek JA, Cox JE, Mashek DG, Kardon G, Boudina S, Zeczycki TN, Rutter J, Shaikh SR, Vance JE, Drummond MJ, Neufer PD, Funai K (2019) Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity. Sci Adv 5:eaax8352. | LEAK OXPHOS | F N S DQ CIV NS ROX | Permeabilized tissue Isolated mitochondria | Mouse | Skeletal muscle |
Svab 2019 Neurochem Res | 2019 | Svab G, Doczi J, Gerencser AA, Ambrus A, Gallyas F, Sümegi B, Tretter L (2019) The mitochondrial targets of neuroprotective drug vinpocetine on primary neuron cultures, brain capillary endothelial cells, synaptosomes, and brain mitochondria. Neurochem Res 44:2435-47. | LEAK OXPHOS ET | N S | Isolated mitochondria Intact cells | Guinea pig | Nervous system |
Zhu 2019 Aging Cell | 2019 | Zhu B, Li Y, Xiang L, Zhang J, Wang L, Guo B, Liang M, Chen L, Xiang L, Dong J, Liu M, Mei W, Li H, Xiang G (2019) Alogliptin improves survival and health of mice on a high-fat diet. Aging Cell 18:e12883. | LEAK OXPHOS ET | N NS S ROX | Isolated mitochondria | Mouse | Liver |
Crescenzo 2019 Mol Neurobiol | 2019 | Crescenzo R, Spagnuolo MS, Cancelliere R, Iannotta L, Mazzoli A, Gatto C, Iossa S, Cigliano L (2019) Effect of initial aging and high-fat/high-fructose diet on mitochondrial bioenergetics and oxidative status in rat brain. Mol Neurobiol 56:7651-63. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Rat | Nervous system |
Miranda-Silva 2019 Acta Physiologica | 2019 | Miranda-Silva D, Wüst RCI, Conceição G, Gonçalves-Rodrigues P, Gonçalves N, Gonçalves A, Kuster DWD, Leite-Moreira AF, van der Velden J, de Sousa Beleza JM, Magalhães J, Stienen GJM, Falcão-Pires I (2019) Disturbed cardiac mitochondrial and cytosolic calcium handling in a metabolic risk-related rat model of heart failure with preserved ejection fraction. Acta Physiol e13378. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact organ Permeabilized tissue Isolated mitochondria | Rat | Heart |
Holsgrove 2019 Thesis | 2019 | Holsgrove A (2019) The effect of temperature on cardiac energetics in the rainbow trout, Onchorhynchus mykiss. Phd Thesis 166. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Fishes | Heart |
Ahn 2019 J Cachexia Sarcopenia Muscle | 2019 | Ahn B, Ranjit R, Premkumar P, Pharaoh G, Piekarz KM, Matsuzaki S, Claflin DR, Riddle K, Judge J, Bhaskaran S, Satara Natarajan K, Barboza E, Wronowski B, Kinter M, Humphries KM, Griffin TM, Freeman WM, Richardson A, Brooks SV, Van Remmen H (2019) Mitochondrial oxidative stress impairs contractile function but paradoxically increases muscle mass via fiber branching. J Cachexia Sarcopenia Muscle 10:411-28. | OXPHOS LEAK | N S CIV NS ROX | Isolated mitochondria | Mouse | Skeletal muscle |
Hirschi 2019 Biol Reprod | 2019 | Hirschi KM, Tsai KYF, Davis T, Clark JC, Knowlton MN, Bikman BT, Reynolds PR, Arroyo JA (2019) Growth arrest specific protein (Gas)-6/AXL signaling induces preeclampsia (PE) in rats. Biol Reprod 102:199-210. | LEAK OXPHOS ET | N S NS | Permeabilized cells Permeabilized tissue | Rat | Genital |
Nunes 2019 Oxid Med Cell Longev | 2019 | Nunes MEM, Schimith LE, da Costa-Silva DG, Lopes AR, Leandro LP, Martins IK, de Mello RS, Hartmann DD, de Carvalho NR, Carvalho da Rosa P, Trevisan R, Di Giulio RT, Posser T, Franco JL (2019) Acute exposure to permethrin modulates behavioral functions, redox, and bioenergetics parameters and induces DNA damage and cell death in larval zebrafish. Oxid Med Cell Longev 2019:9149203. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Homogenate | Zebrafish | |
Chang 2019 Br J Anaesth | 2019 | Chang L, Daly C, Miller DM, Allen PD, Boyle JP, Hopkins PM, Shaw MA (2019) Permeabilised skeletal muscle reveals mitochondrial deficiency in malignant hyperthermia-susceptible individuals. Br J Anaesth 122:613-21. | LEAK OXPHOS ET | N S CIV NS ROX | Human | Skeletal muscle | |
Dilberger 2019 Nutrients | 2019 | Dilberger B, Passon M, Asseburg H, Silaidos CV, Schmitt F, Schmiedl T, Schieber A, Eckert GP (2019) Polyphenols and metabolites enhance survival in rodents and nematodes-impact of mitochondria. Nutrients 11:E1886. | LEAK OXPHOS ET | N S CIV NS | Isolated mitochondria | Caenorhabditis elegans | |
Halle 2019 Am J Physiol Regul Integr Comp Physiol | 2019 | Halle JL, Pena GS, Paez HG, Castro AJ, Rossiter HB, Visavadiya NP, Whitehurst MA, Khamoui AV (2019) Tissue-specific dysregulation of mitochondrial respiratory capacity and coupling control in colon-26 tumor-induced cachexia. Am J Physiol Regul Integr Comp Physiol 317:R68-R82. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue Intact cells | Mouse | Skeletal muscle Liver Fat |
Liu 2019 J Ethnopharmacol | 2019 | Liu M, Yu S, Wang J, Qiao J, Liu Y, Wang S, Zhao Y (2019) Ginseng protein protects against mitochondrial dysfunction and neurodegeneration by inducing mitochondrial unfolded protein response in Drosophila melanogaster PINK1 model of Parkinson's disease. J Ethnopharmacol 247:112213. | OXPHOS | N S | Homogenate | Drosophila | |
Gregg 2019 J Biol Chem | 2019 | Gregg T, Sdao SM, Dhillon RS, Rensvold JW, Lewandowski SL, Pagliarini DJ, Denu JM, Merrins MJ (2019) Obesity-dependent CDK1 signaling stimulates mitochondrial respiration at Complex I in pancreatic β-cells. J Biol Chem 294:4656-66. | OXPHOS ET LEAK | N S NS ROX | Permeabilized tissue | Mouse | Islet cell;pancreas;thymus |
Paradis 2019 Antioxidants (Basel) | 2019 | Paradis S, Charles AL, Georg I, Goupilleau F, Meyer A, Kindo M, Laverny G, Metzger D, Geny B (2019) Aging exacerbates ischemia-reperfusion-induced mitochondrial respiration impairment in skeletal muscle. Antioxidants (Basel) 8:E168. | LEAK OXPHOS | N S CIV | Permeabilized tissue | Mouse | Skeletal muscle |
Tomasic 2019 Biochim Biophys Acta Mol Basis Dis | 2019 | Tomašić N, Kotarsky H, de Oliveira Figueiredo R, Hansson E, Mörgelin M, Tomašić I, Kallijärvi J, Elmér E, Jauhiainen M, Eklund EA, Fellman V (2019) Fasting reveals largely intact systemic lipid mobilization mechanisms in respiratory chain complex III deficient mice. Biochim Biophys Acta Mol Basis Dis 1866:165573. | LEAK OXPHOS ET | N S NS | Isolated mitochondria | Mouse | Liver |
Zhao 2019 Basic Res Cardiol | 2019 | Zhao J, Gao JL, Zhu JX, Zhu HB, Peng X, Jiang M, Fu Y, Xu J, Mao XH, Hu N, Ma MH, Dong DL (2019) The different response of cardiomyocytes and cardiac fibroblasts to mitochondria inhibition and the underlying role of STAT3. Basic Res Cardiol 114:12. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact cells Permeabilized cells | Rat | Heart Fibroblast |
Kopinski 2019 Proc Natl Acad Sci U S A | 2019 | Kopinski PK, Janssen KA, Schaefer PM, Trefely S, Perry CE, Potluri P, Tintos-Hernandez JA, Singh LN, Karch KR, Campbell SL, Doan MT, Jiang H, Nissim I, Nakamaru-Ogiso E, Wellen KE, Snyder NW, Garcia BA, Wallace DC (2019) Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy. Proc Natl Acad Sci U S A 116:16028-35. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells | Human | Other cell lines |
Penniman 2019 Mol Metab | 2019 | Penniman CM, Suarez Beltran PA, Bhardwaj G, Junck TL, Jena J, Poro K, Hirshman MF, Goodyear LJ, O'Neill BT (2019) Loss of FoxOs in muscle reveals sex-based differences in insulin sensitivity but mitigates diet-induced obesity. Mol Metab 30:203-220. | LEAK OXPHOS ET | F N S NS | Permeabilized tissue Isolated mitochondria | Mouse | Skeletal muscle |
Ferey 2019 Am J Physiol Heart Circ Physiol | 2019 | Ferey J, Boudoures AL, Reid M, Drury A, Scheaffer S, Modi Z, Kovacs A, Pietka T, DeBosch BJ, Thompson MD, Diwan A, Moley KH (2019) Maternal high-fat, high-sucrose diet induces transgenerational cardiac mitochondrial dysfunction independent of maternal mitochondrial inheritance. Am J Physiol Heart Circ Physiol 316:H1202-H1210. | LEAK OXPHOS | N S NS | Permeabilized tissue | Mouse | Heart |
Ling 2019 Am J Clin Nutr | 2019 | Ling Y, Carayol J, Galusca B, Canto C, Montaurier C, Matone A, Vassallo I, Minehira K, Alexandre V, Cominetti O, Núñez Galindo A, Corthésy J, Dayon L, Charpagne A, Métairon S, Raymond F, Descombes P, Casteillo F, Peoc'h M, Palaghiu R, Féasson L, Boirie Y, Estour B, Hager J, Germain N, Gheldof N (2019) Persistent low body weight in humans is associated with higher mitochondrial activity in white adipose tissue. Am J Clin Nutr 110:605-16. | LEAK OXPHOS ET | N S NS | Permeabilized tissue | Human | Skeletal muscle Fat |
Monteiro 2019 J Bioenerg Biomembr | 2019 | Monteiro J, Assis-de-Lemos G, de-Souza-Ferreira E, Marques AM, Neves GA, Silveira MS, Galina A (2019) Energization by multiple substrates and calcium challenge reveal dysfunctions in brain mitochondria in a model related to acute psychosis. J Bioenerg Biomembr 52:1-15. | LEAK OXPHOS | N S NS ROX | Isolated mitochondria | Mouse | Nervous system |
Ng 2019 J Biol Chem | 2019 | Ng J, Kaur H, Collier T, Chang K, Brooks AES, Allison JR, Brimble MA, Hickey A, Birch NP (2019) Site-specific glycations of Aβ1-42 affect fibril formation and are neurotoxic. J Biol Chem 294:8806-18. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Human | Neuroblastoma |
Chabi 2019 MitoFit Preprint Arch EA | 2019 | Chabi Béatrice, Ost M, Gama-Perez P, Dahdah N, Lemieux H, Holody CD, Carpenter RG, Tepp K, Puurand M, Kaambre T, Dubouchaud H, Cortade F, Pesta D, Calabria E, Casado M, Fernandez-Ortiz M, Acuña-Castroviejo D, Villena JA, Grefte S, Keijer J, O'Brien K, Sowton A, Murray AJ, Campbell MD, Marcinek DJ, Nollet E, Wüst R, Dayanidhi S, Gnaiger E, Doerrier C, Garcia-Roves PM (2019) Generating reference values on mitochondrial respiration in permeabilized muscle fibers. https://doi.org/10.26124/mitofit:ea19.MitoEAGLE.0001 | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Lemieux 2019 bioRxiv | 2019 | Lemieux H, Subarsky P, Doblander C, Wurm M, Troppmair J, Gnaiger E (2019) Mitochondrial respiratory function as an early biomarker of apoptosis induced by growth factor removal. bioRxiv doi: https://doi.org/10.1101/151480 . | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Mouse | Blood cells |
Belosludtsev 2019 Cells | 2019 | Belosludtsev KN, Talanov EY, Starinets VS, Agafonov AV, Dubinin MV, Belosludtseva NV (2019) Transport of Ca2+ and Ca2+-dependent permeability transition in rat liver mitochondria under the streptozotocin-induced type I Diabetes. Cells 8:E1014. | LEAK | S | Isolated mitochondria | Rat | Liver |
Powers 2019 Neurourol Urodyn | 2019 | Powers SA, Ryan TE, Pak ES, Fraser MO, McClung JM, Hannan JL (2019) Chronic high-fat diet decreased detrusor mitochondrial respiration and increased nerve-mediated contractions. Neurourol Urodyn 38:1524-32. | LEAK OXPHOS | N S CIV NS | Homogenate | Mouse | Other cell lines |
Doig 2019 bioRxiv | 2019 | Doig CD, Zelinska AE, Oakey LA, Fletcher RS, El Hassan Y, Garten A, Cartwright D, Heising S, Tennant DA, Watson D, Adamski J, Lavery GG (2019) Induction of the nicotinamide riboside kinase NAD+ salvage pathway in skeletal muscle of H6PDH KO mice. bioRxiv doi: https://doi.org/10.1101/567297 . | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Scavuzzo 2019 J Neurophysiol | 2019 | Scavuzzo CJ, Leblancq MJ, Nargang F, Lemieux H, Hamilton TJ, Dickson CT (2019) The amnestic agent anisomycin disrupts intrinsic membrane properties of hippocampal neurons via a loss of cellular energetics. J Neurophysiol 122:1123-35. | LEAK OXPHOS | N S CIV NS ROX | Homogenate | Rat | Nervous system |
Hsu 2019 J Clin Med | 2019 | Hsu CC, Tsai HH, Fu TC, Wang JS (2019) Exercise training enhances platelet mitochondrial bioenergetics in stroke patients: a randomized controlled trial. J Clin Med 8:E2186. | LEAK OXPHOS ET | F N S Gp NS ROX | Permeabilized cells | Human | Platelet Blood cells |
Baekkerud 2019 Cardiovasc Toxicol | 2019 | Bækkerud FH, Salerno S, Ceriotti P, Morland C, Storm-Mathisen J, Bergersen LH, Høydal MA, Catalucci D, Stølen TO (2019) High intensity interval training ameliorates mitochondrial dysfunction in the left ventricle of mice with type 2 diabetes. Cardiovasc Toxicol 19:422-31. | LEAK OXPHOS | N S CIV NS ROX | Permeabilized tissue | Mouse | Heart |
Sambeat 2019 Nat Commun | 2019 | Sambeat A, Ratajczak J, Joffraud M, Sanchez-Garcia JL, Giner MP, Valsesia A, Giroud-Gerbetant J, Valera-Alberni M, Cercillieux A, Boutant M, Kulkarni SS, Moco S, Canto C (2019) Endogenous nicotinamide riboside metabolism protects against diet-induced liver damage. Nat Commun 10:4291. | LEAK OXPHOS ET | N S NS | Permeabilized tissue Homogenate | Mouse | Skeletal muscle Liver |
Mann 2019 Oncogene | 2019 | Mann J, Githaka JM, Buckland TW, Yang N, Montpetit R, Patel N, Li L, Baksh S, Godbout R, Lemieux H, Goping IS (2019) Non-canonical BAD activity regulates breast cancer cell and tumor growth via 14-3-3 binding and mitochondrial metabolism. Oncogene 38:3325-39. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX F | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell |
Jiang 2019 EMBO Rep | 2019 | Jiang S, Koolmeister C, Misic J, Siira S, Kühl I, Silva Ramos E, Miranda M, Jiang M, Posse V, Lytovchenko O, Atanassov I, Schober FA, Wibom R, Hultenby K, Milenkovic D, Gustafsson CM, Filipovska A, Larsson NG (2019) TEFM regulates both transcription elongation and RNA processing in mitochondria. EMBO Rep 20:e48101. | LEAK OXPHOS ET | N S | Isolated mitochondria | Mouse | Heart |
Poudel 2019 Can J Physiol Pharmacol | 2019 | Poudel A, Zhou JY, Mekala N, Welchko R, Rosca MG, Li L (2019) Berberine hydrochloride protects against cytokine-induced inflammation through multiple pathways in undifferentiated C2C12 myoblast cells. Can J Physiol Pharmacol 97:699-707. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells | Mouse | Skeletal muscle |
Magga 2019 Mol Ther | 2019 | Magga J, Vainio L, Kilpiö T, Hulmi JJ, Taponen S, Lin R, Räsänen M, Szabó Z, Gao E, Rahtu-Korpela L, Alakoski T, Ulvila J, Laitinen M, Pasternack A, Koch WJ, Alitalo K, Kivelä R, Ritvos O, Kerkelä R (2019) Systemic blockade of ACVR2B ligands protects myocardium from acute ischemia-reperfusion injury. Mol Ther 27:600-10. | LEAK OXPHOS ET | N S NS | Homogenate | Mouse | Heart |
Teh 2019 Mol Cancer Ther | 2019 | Teh JT, Zhu WL, Newgard CB, Casey PJ, Wang M (2019) Respiratory capacity and reserve predict cell sensitivity to mitochondria inhibitors: mechanism-based markers to identify metformin-responsive cancers. Mol Cancer Ther 18:693-705. | LEAK ROUTINE OXPHOS ET | N S DQ ROX | Intact cells Permeabilized cells Permeabilized tissue | Human Mouse | Other cell lines |
Andreazza 2019 Nat Commun | 2019 | Andreazza S, Samstag CL, Sanchez-Martinez A, Fernandez-Vizarra E, Gomez-Duran A, Lee JJ, Tufi R, Hipp MJ, Schmidt EK, Nicholls TJ, Gammage PA, Chinnery PF, Minczuk M, Pallanck LJ, Kennedy SR, Whitworth AJ (2019) Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila. https://doi.org/10.1038/s41467-019-10857-y | OXPHOS | N S | Homogenate | Drosophila | |
Qaed 2019 Oxid Med Cell Longev | 2019 | Qaed E, Wang J, Almoiliqy M, Song Y, Liu W, Chu P, Alademi S, Alademi M, Li H, Alshwmi M, Al-Azab M, Ahsan A, Mahdi S, Han G, Niu M, Ali A, Shopit A, Wang H, Li X, Qaid A, Ma X, Li T, Peng J, Ma J, Zhang J, Tang Z (2019) Phosphocreatine improves cardiac dysfunction by normalizing mitochondrial respiratory function through JAK2/STAT3 signaling pathway in vivo and in vitro. Oxid Med Cell Longev 2019:6521218. | LEAK OXPHOS ET ROUTINE | N S NS ROX | Homogenate Isolated mitochondria Permeabilized cells Intact cells | Rat | Heart |
Chao 2019 J Appl Physiol (1985) | 2019 | Chao T, Burmeister DM, Corona BT, Greising SM (2019) Oxidative pathophysiology following volumetric muscle loss injury in a porcine model. J Appl Physiol (1985) 126:1541-49. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Pig | Skeletal muscle |
Bouitbir 2019 Toxicology | 2019 | Bouitbir J, Alshaikhali A, Panajatovic MV, Abegg VF, Paech F, Krähenbühl S (2019) Mitochondrial oxidative stress plays a critical role in the cardiotoxicity of sunitinib. Toxicology 426:152281. | LEAK OXPHOS | N S CIV NS ROX | Permeabilized cells Permeabilized tissue | Rat Mouse | Heart |
Isei 2019 Free Radic Biol Med | 2019 | Isei MO, Kamunde C (2019) Effects of copper and temperature on heart mitochondrial hydrogen peroxide production. Free Radic Biol Med 147:114-28. | N S ROX | Isolated mitochondria | Fishes | Heart | |
Ma 2019 Biochem Biophys Res Commun | 2019 | Ma T, Lin S, Wang B, Wang Q, Xia W, Zhang H, Cui Y, He C, Wu H, Sun F, Zhao Z, Gao P, Zhu Z, Liu D (2019) TRPC3 deficiency attenuates high salt-induced cardiac hypertrophy by alleviating cardiac mitochondrial dysfunction. Biochem Biophys Res Commun 519:674-81. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells | Mouse | Heart |
Haberman 2019 Nat Commun | 2019 | Haberman Y, Karns R, Dexheimer PJ, Schirmer M, Somekh J, Jurickova I, Braun T, Novak E, Bauman L, Collins MH, Mo A, Rosen MJ, Bonkowski E, Gotman N, Marquis A, Nistel M, Rufo PA, Baker SS, Sauer CG, Markowitz J, Pfefferkorn MD, Rosh JR, Boyle BM, Mack DR, Baldassano RN, Shah S, Leleiko NS, Heyman MB, Grifiths AM, Patel AS, Noe JD, Aronow BJ, Kugathasan S, Walters TD, Gibson G, Thomas SD, Mollen K, Shen-Orr S, Huttenhower C, Xavier RJ, Hyams JS, Denson LA (2019) Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response. Nat Commun 10:38. | OXPHOS ET | N S NS | Homogenate | Human | Endothelial;epithelial;mesothelial cell |
Hafen 2019 J Appl Physiol (1985) | 2019 | Hafen PS, Abbott K, Bowden JA, Lopiano R, Hancock CR, Hyldahl RD (2019) Daily heat treatment maintains mitochondrial function and attenuates atrophy in human skeletal muscle subjected to immobilization. J Appl Physiol (1985) 127:47-57. https://doi.org/10.1152/japplphysiol.01098.2018 | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Ederle 2019 J Clin Med | 2019 | Ederle C, Charles AL, Khayath N, Poirot A, Meyer A, Clere-Jehl R, Andres E, De Blay F, Geny B (2019) Mitochondrial function in peripheral blood mononuclear cells (PBMC) is enhanced, together with increased reactive oxygen species, in severe asthmatic patients in exacerbation. J Clin Med 8:E1613. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Human | Blood cells |
Tyrrell 2019 Circ Res | 2019 | Tyrrell DJ, Blin M, Song J, Wood S, Zhang M, Beard DA, Goldstein D (2019) Age-associated mitochondrial dysfunction accelerates atherogenesis. Circ Res 126:298–314. | OXPHOS ET | N S NS ROX | Mouse | Endothelial;epithelial;mesothelial cell | |
Desquiret-Dumas 2019 Biochim Biophys Acta Mol Basis Dis | 2019 | Desquiret-Dumas V, Leman G, Wetterwald C, Chupin S, Lebert A, Khiati S, Le Mao M, Geffroy G, Kane MS, Chevrollier A, Goudenege D, Gadras C, Tessier L, Barth M, Leruez S, Amati-Bonneau P, Henrion D, Bonneau D, Procaccio V, Reynier P, Lenaers G, Gueguen N (2019) Warburg-like effect is a hallmark of complex I assembly defects. Biochim Biophys Acta Mol Basis Dis 1865:2475-89. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
Kumari 2019 Am J Physiol Heart Circ Physiol | 2019 | Kumari S, Braun RK, Tetri L, Barton GP, Hacker TA, Goss KN (2019) Bimodal right ventricular dysfunction after postnatal hyperoxia exposure: implications for the preterm heart. Am J Physiol Heart Circ Physiol 317:H1272-81. | LEAK OXPHOS ET | N S CIV ROX | Permeabilized tissue | Rat | Heart |
Cedrone 2019 Thesis | 2019 | Cedrone M (2019) Low birth weight and post-natal diet induced alterations in skeletal muscle oxygen consumption and fiber type composition. Master's Thesis 83. | LEAK OXPHOS | N S | Permeabilized tissue Intact cells | Guinea pig Mouse | Skeletal muscle |
Rose 2019 Am J Physiol Endocrinol Metab | 2019 | Rose S, Carvalho E, Diaz EC, Cotter M, Bennuri SC, Azhar G, Frye RE, Adams SH, Børsheim E (2019) A comparative study of mitochondrial respiration in circulating blood cells and skeletal muscle fibers in women. Am J Physiol Endocrinol Metab 317:E503-E512. https://doi.org/10.1152/ajpendo.00084.2019 | LEAK OXPHOS ET | F N S NS ROX | Permeabilized cells Permeabilized tissue Intact cells | Human | Skeletal muscle Blood cells Platelet |
Bettink 2019 Mitochondrion | 2019 | Bettink MAW, Harms FA, Dollee N, Specht PAC, Raat NJH, Schoonderwoerd GC, Mik EG (2019) Non-invasive versus ex vivo measurement of mitochondrial function in an endotoxemia model in rat: toward monitoring of mitochondrial therapy. Mitochondrion 50:149-57. | LEAK OXPHOS ET | N S | Homogenate | Rat | Skeletal muscle |
Fernando 2019 Exp Gerontol | 2019 | Fernando R, Drescher C, Deubel S, Jung T, Ost M, Klaus S, Grune T, Castro JP (2019) Low proteasomal activity in fast skeletal muscle fibers is not associated with increased age-related oxidative damage. Exp Gerontol 117:45-52. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Zhang 2019 Nephron | 2019 | Zhang R, Wang X, Gao Q, Jiang H, Zhang S, Lu M, Liu F, Xue X (2019) Taurine supplementation reverses diabetes-induced podocytes injury via modulation of the CSE/TRPC6 axis and improvement of mitochondrial function. Nephron 144:84-95. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Intact cells Permeabilized cells | Mouse | Kidney |
Pedrotti 2019 Sci Adv | 2019 | Pedrotti S, Caccia R, Neguembor MV, Garcia-Manteiga JM, Ferri G, de Palma C, Canu T, Giovarelli M, Marra P, Fiocchi A, Molineris I, Raso M, Sanvito F, Doglioni C, Esposito A, Clementi E, Gabellini D (2019) The Suv420h histone methyltransferases regulate PPAR-γ and energy expenditure in response to environmental stimuli. Sci Adv 5:eaav1472. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact cells | Mouse | Fat |
Chao 2019 Am J Physiol Cell Physiol | 2019 | Chao T, Gomez BI, Heard TC, Smith BW, Dubick MA, Burmeister DM (2019) Burn-induced reductions in mitochondrial abundance and efficiency are more pronounced with small volumes of colloids in swine. Am J Physiol Cell Physiol 317:C1229-38. | LEAK OXPHOS ET | F N S NS | Permeabilized tissue | Pig | Heart |
Jansen 2019 Am J Physiol Heart Circ Physiol | 2019 | Jansen KM, Moreno S, Garcia-Roves PM, Larsen TS (2019) Dietary Calanus oil recovers metabolic flexibility and rescues post-ischemic cardiac function in obese female mice. Am J Physiol Heart Circ Physiol 317:H290-H299. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Mouse | Heart |
Mazzoli 2019 Nutrients | 2019 | Mazzoli A, Crescenzo R, Cigliano L, Spagnuolo MS, Cancelliere R, Gatto C, Iossa S (2019) Early hepatic oxidative stress and mitochondrial changes following western diet in middle aged rats. Nutrients 11:E2670. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Rat | Liver |
Kharechkina 2019 Biochim Biophys Acta Gen Subj | 2019 | Kharechkina ES, Nikiforova AB, Teplova VV, Odinokova IV, Krestinina OV, Baburina YL, Kruglova SA, Kruglov AG (2019) Regulation of permeability transition pore opening in mitochondria by external NAD(H). Biochim Biophys Acta Gen Subj 1863:771-83. | LEAK OXPHOS ET | S | Isolated mitochondria | Rat | Liver |
Doerrier 2019 MitoFit Preprint Arch EA | 2019 | Doerrier C, Gama-Perez P, Distefano G, Pesta D, Soendergaard SD, Chroeis KM, Gonzalez-Franquesa A, Goodpaster BH, Coen P, Larsen S, Gnaiger E, Garcia-Roves PM (2019) Inter-laboratory harmonization of respiratory protocols in permeabilized human muscle fibers. https://doi.org/10.26124/mitofit:ea19.MiPSchool.0009 | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Deutschman 2019 J Cell Sci | 2019 | Deutschman E, Ward JR, Kumar A, Ray G, Welch N, Lemieux ME, Dasarathy S, Longworth MS (2019) Condensin II protein dysfunction impacts mitochondrial respiration and mitochondrial oxidative stress responses. J Cell Sci 132:jcs233783. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell |
Anderson 2019 Acta Neuropathol | 2019 | Anderson CJ, Bredvik K, Burstein SR, Davis C, Meadows SM, Dash J, Case L, Milner TA, Kawamata H, Zuberi A, Piersigilli A, Lutz C, Manfredi G (2019) ALS/FTD mutant CHCHD10 mice reveal a tissue-specific toxic gain-of-function and mitochondrial stress response. Acta Neuropathol 138:103-21. | LEAK | N S | Isolated mitochondria | Mouse | Heart |
Zeng 2019 Toxicol Rep | 2019 | Zeng R, Zhou Q, Zhang W, Fu X, Wu Q, Lu Y, Shi J, Zhou S (2019) Icariin-mediated activation of autophagy confers protective effect on rotenone induced neurotoxicity in vivo and in vitro. Toxicol Rep 6:637-44. | OXPHOS | S | Isolated mitochondria Intact cells | Rat | Nervous system |
Bukowska 2019 Eur J Pharmacol | 2019 | Bukowska A, Schild L, Bornfleth P, Peter D, Wiese-Rischke C, Gardemann A, Isermann B, Walles T, Goette A (2019) Activated clotting factor X mediates mitochondrial alterations and inflammatory responses via protease-activated receptor signaling in alveolar epithelial cells. Eur J Pharmacol 869:172875. | OXPHOS | S | Intact cells | Human | Lung;gill Endothelial;epithelial;mesothelial cell |
Schweitzer 2019 FASEB J | 2019 | Schweitzer GG, Collier SL, Chen Z, McCommis KS, Pittman SK, Yoshino J, Matkovich SJ, Hsu FF, Chrast R, Eaton JM, Harris TE, Weihl CC, Finck BN (2019) Loss of lipin 1-mediated phosphatidic acid phosphohydrolase activity in muscle leads to skeletal myopathy in mice. FASEB J 33:652-67. | LEAK OXPHOS ET | N S NS | Permeabilized tissue | Mouse | Skeletal muscle |
Fisar 2019 Clin Biochem | 2019 | Fišar Z, Jirák R, Zvěřová M, Setnička V, Habartová L, Hroudová J, Vaníčková Z, Raboch J (2019) Plasma amyloid beta levels and platelet mitochondrial respiration in patients with Alzheimer's disease. Clin Biochem 72:71-80. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Platelet Blood cells |