Difference between revisions of "Warburg effect"
| Line 17: | Line 17: | ||
Perhaps an extended definition is required compared to the Wikipedia definition of the [http://en.wikipedia.org/wiki/Warburg_effect Warburg effect]. | Perhaps an extended definition is required compared to the Wikipedia definition of the [http://en.wikipedia.org/wiki/Warburg_effect Warburg effect]. | ||
== | ==From the literature== | ||
[ | * [[Fang 2010 Cell|Fang M, Shen Z, Huang S, Zhao L, Chen S, Mak TW, Wang X (2010) The ER UDPase ENTPD5 promotes protein N-glycosylation, the Warburg effect, and proliferation in the PTEN pathway. Cell 143: 711-724]]. | ||
::Warburg effect: "elevation of aerobic glycolysis seen in tumor cells"; "elevated lactate production under aerobic conditions". | |||
[http://www.bioblast.at/index.php/VanBeek_MiP2010 van Beek JHGM (2010) Computational model predictions of metabolic fluxes connecting cytosol and mitochondrial matrix under ‘Warburg effect’ conditions. Mitochondr. Physiol. Network 15.06: 80.] | * [http://www.bioblast.at/index.php/Vaupel_MiP2010 Vaupel P, Mayer A (2010) Evidence against a mitochondrial dysfunction in cancer cells as a hallmark of malignant growth. Mitochondr. Physiol. Network 15.06: 79.] | ||
* [http://www.bioblast.at/index.php/VanBeek_MiP2010 van Beek JHGM (2010) Computational model predictions of metabolic fluxes connecting cytosol and mitochondrial matrix under ‘Warburg effect’ conditions. Mitochondr. Physiol. Network 15.06: 80.] | |||
Revision as of 12:58, 7 February 2012
- high-resolution terminology - matching measurements at high-resolution
Warburg effect
Description
Requires definition
Reference: http://en.wikipedia.org/wiki/Warburg_effect
MitoPedia methods:
Respirometry
Labels:
Stress:Cancer; Apoptosis; Cytochrome c"Cancer; Apoptosis; Cytochrome c" is not in the list (Cell death, Cryopreservation, Ischemia-reperfusion, Permeability transition, Oxidative stress;RONS, Temperature, Hypoxia, Mitochondrial disease) of allowed values for the "Stress" property.
Preparation: Intact Cell; Cultured; Primary"Intact Cell; Cultured; Primary" is not in the list (Intact organism, Intact organ, Permeabilized cells, Permeabilized tissue, Homogenate, Isolated mitochondria, SMP, Chloroplasts, Enzyme, Oxidase;biochemical oxidation, ...) of allowed values for the "Preparation" property.
Regulation: Respiration; OXPHOS; ETS Capacity"Respiration; OXPHOS; ETS Capacity" is not in the list (Aerobic glycolysis, ADP, ATP, ATP production, AMP, Calcium, Coupling efficiency;uncoupling, Cyt c, Flux control, Inhibitor, ...) of allowed values for the "Respiration and regulation" property., Aerobic and Anaerobic Metabolism"Aerobic and Anaerobic Metabolism" is not in the list (Aerobic glycolysis, ADP, ATP, ATP production, AMP, Calcium, Coupling efficiency;uncoupling, Cyt c, Flux control, Inhibitor, ...) of allowed values for the "Respiration and regulation" property.
Comment
Perhaps an extended definition is required compared to the Wikipedia definition of the Warburg effect.
From the literature
- Warburg effect: "elevation of aerobic glycolysis seen in tumor cells"; "elevated lactate production under aerobic conditions".
